Patents by Inventor Yoshio Yamauchi
Yoshio Yamauchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10974885Abstract: The delaminatable container is capable of suppressing deterioration of the contents under high-temperature environment. The delaminatable container includes a container body; and a tubular outer case being installed in the container body; wherein: the container body includes an outer shell and an inner bag, and the inner bag shrinks as contents decrease.Type: GrantFiled: March 14, 2018Date of Patent: April 13, 2021Assignee: KYORAKU CO., LTD.Inventors: Yoshio Yamauchi, Teruhisa Hanafusa, Kouichiro Yoshida, Yusuke Hiraina
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Publication number: 20200047966Abstract: The delaminatable container is capable of suppressing deterioration of the contents under high-temperature environment. The delaminatable container includes a container body; and a tubular outer case being installed in the container body; wherein: the container body includes an outer shell and an inner bag, and the inner bag shrinks as contents decrease.Type: ApplicationFiled: March 14, 2018Publication date: February 13, 2020Applicant: KYORAKU CO., LTD.Inventors: Yoshio YAMAUCHI, Teruhisa HANAFUSA, Kouichiro YOSHIDA, Yusuke HIRAINA
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Patent number: 10202218Abstract: Provided is a delamination container having improved oxygen barrier properties. The present invention provides a delamination container provided with a container body having an outer shell and an inner pouch, the inner pouch being adapted to delaminate from the outer shell and contract in association with a decrease of the contents, wherein the inner layer constituting the inner pouch is provided with, in order from the container outer surface side, an outside layer, an adhesive layer, and an inside layer. The outside layer includes an EVOH layer, and the inside layer has a thickness of 60-200 ?m and a flexural modulus of 250 MPa or less, the value (thickness of the inside layer/thickness of the EVOH layer) being 1.1-5, and the total thickness of the inside layer being 100-250 ?m.Type: GrantFiled: January 22, 2016Date of Patent: February 12, 2019Assignee: KYORAKU CO., LTD.Inventors: Tetsuaki Eguchi, Shinsuke Taruno, Yuji Yoneoka, Yoshio Yamauchi
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Publication number: 20180016050Abstract: Provided is a delamination container having improved oxygen barrier properties. The present invention provides a delamination container provided with a container body having an outer shell and an inner pouch, the inner pouch being adapted to delaminate from the outer shell and contract in association with a decrease of the contents, wherein the inner layer constituting the inner pouch is provided with, in order from the container outer surface side, an outside layer, an adhesive layer, and an inside layer. The outside layer includes an EVOH layer, and the inside layer has a thickness of 60-200 ?m and a flexural modulus of 250 MPa or less, the value (thickness of the inside layer/thickness of the EVOH layer) being 1.1-5, and the total thickness of the inside layer being 100-250 ?m.Type: ApplicationFiled: January 22, 2016Publication date: January 18, 2018Applicant: KYORAKU CO., LTD.Inventors: Tetsuaki EGUCHI, Shinsuke TARUNO, Yuji YONEOKA, Yoshio YAMAUCHI
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Patent number: 9409702Abstract: A rectangular thin panel conveyance unit includes a plurality of sets of four corner modules, and vibration suppressing bodies for rectangular thin panels in a fixed shape. The corner module has a support surface to support each corner portion of the rectangular thin panel from a lower side. At each corner portion, stacking the corner modules in a vertical direction stacks a plurality of rectangular thin panels in the vertical direction. The vibration suppressing bodies have a thickness equal to or less than the distance between the support surfaces of the corner modules vertically adjacent to one another; and are disposed on each of a top surface and an inferior surface of the rectangular thin panel such that the vibration suppressing body faces a planar portion of each rectangular thin panel to restrict vertical amplitude of vibration of the rectangular thin panel within a predetermined range.Type: GrantFiled: November 29, 2011Date of Patent: August 9, 2016Assignee: KYORAKU CO., LTD.Inventors: Masaaki Sueoka, Yoshio Yamauchi
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Patent number: 8880353Abstract: Disclosed are an apparatus for the identification of a ribonucleic acid, whereby not only the molecular weights of digestion products, from which nothing but the nucleic acid residue composition can be understood, but also nucleic acid residue sequence data is obtained from a product ion mass set and thus the identification reliability for the individual digestion products can be remarkably improved; a method for the identification of a ribonucleic acid; and a program and system for the identification of a ribonucleic acid.Type: GrantFiled: April 17, 2009Date of Patent: November 4, 2014Assignees: Riken, Tokyo Metropolitan University, National University Corporation Tokyo University of Agriculture and TechnologyInventors: Hiroshi Nakayama, Misaki Akiyama, Toshiaki Isobe, Masato Taoka, Yoshio Yamauchi, Nobuhiro Takahashi, Hideaki Ishikawa
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Publication number: 20130327669Abstract: A rectangular thin panel conveyance unit that prevents damage of a plurality of rectangular thin panels while conveying the plurality of rectangular thin panels that are stacked so as not to contact one another. A rectangular thin panel conveyance unit includes a plurality of sets of four corner modules, and vibration suppressing bodies for rectangular thin panels in a fixed shape. The corner module has a support surface to support each corner portion of the rectangular thin panel from a lower side. At each corner portion, stacking the corner modules in a columnar shape in the vertical direction stacks a plurality of rectangular thin panels in the vertical direction. At this time, the vibration suppressing body has the thickness that is equal to or less than the distance between the support surfaces of the corner modules adjacent to one another in the vertical direction.Type: ApplicationFiled: November 29, 2011Publication date: December 12, 2013Applicant: KYORAKU CO., LTDInventors: Masaaki Sueoka, Yoshio Yamauchi
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Patent number: 8507851Abstract: Nano-electrospray ionization techniques include the introduction of a separation solvent containing a sample to a column-integrated needle having a column filled with a resin for liquid chromatography. The separated sample components are sprayed from the tip of the column-integrated needle toward a sample introduction orifice of a mass spectrometer. An organic solvent is simultaneously introduced to a solvent-supplying needle. The organic solvent is supplied from the tip of the solvent-supplying needle to the tip of the column-integrated needle.Type: GrantFiled: August 20, 2012Date of Patent: August 13, 2013Assignee: Tokyo Metropolitan UniversityInventors: Toshiaki Isobe, Yoshio Yamauchi
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Publication number: 20120312983Abstract: Nano-electrospray ionization techniques include the introduction of a separation solvent containing a sample to a column-integrated needle having a column filled with a resin for liquid chromatography. The separated sample components are sprayed from the tip of the column-integrated needle toward a sample introduction orifice of a mass spectrometer. An organic solvent is simultaneously introduced to a solvent-supplying needle. The organic solvent is supplied from the tip of the solvent-supplying needle to the tip of the column-integrated needle.Type: ApplicationFiled: August 20, 2012Publication date: December 13, 2012Applicant: TOKYO METROPOLITAN UNIVERSITYInventors: Toshiaki ISOBE, Yoshio YAMAUCHI
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Patent number: 8269165Abstract: Nano-electrospray ionization techniques include the introduction of a separation solvent containing a sample to a column-integrated needle having a column filled with a resin for liquid chromatography. The separated sample components are sprayed from the tip of the column-integrated needle toward a sample introduction orifice of a mass spectrometer. An organic solvent is simultaneously introduced to a solvent-supplying needle. The organic solvent is supplied from the tip of the solvent-supplying needle to the tip of the column-integrated needle.Type: GrantFiled: June 2, 2010Date of Patent: September 18, 2012Assignee: Tokyo Metropolitan UniversityInventors: Toshiaki Isobe, Yoshio Yamauchi
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Publication number: 20110161273Abstract: Disclosed are an apparatus for the identification of a ribonucleic acid, whereby not only the molecular weights of digestion products, from which nothing but the nucleic acid residue composition can be understood, but also nucleic acid residue sequence data is obtained from a product ion mass set and thus the identification reliability for the individual digestion products can be remarkably improved; a method for the identification of a ribonucleic acid; and a program and system for the identification of a ribonucleic acid.Type: ApplicationFiled: April 17, 2009Publication date: June 30, 2011Inventors: Hiroshi Nakayama, Misaki Akiyama, Toshiaki Isobe, Masato Taoka, Yoshio Yamauchi, Nobuhiro Takahashi, Hideaki Ishikawa
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Publication number: 20110089319Abstract: Nano-electrospray ionization techniques include the introduction of a separation solvent containing a sample to a column-integrated needle having a column filled with a resin for liquid chromatography. The separated sample components are sprayed from the tip of the column-integrated needle toward a sample introduction orifice of a mass spectrometer. An organic solvent is simultaneously introduced to a solvent-supplying needle. The organic solvent is supplied from the tip of the solvent-supplying needle to the tip of the column-integrated needle.Type: ApplicationFiled: June 2, 2010Publication date: April 21, 2011Applicant: TOKYO METROPOLITAN UNIVERSITYInventors: Toshiaki Isobe, Yoshio Yamauchi
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Patent number: 7402250Abstract: It is an object of the present invention to improve the performance of gradient liquid transfer in nano/micro liquid chromatographs when solvents are mixed. In a gradient liquid transfer device and method for a nano/micro liquid chromatograph, an opening and closing unit (160) capable of opening and closing a solvent passage (150) for transferring a secondary solvent is provided in the vicinity of a solvent mixing section (152) in a liquid transfer system (130); a passage from a metering pump (146) of a liquid transfer section (142) to the opening and closing unit (160) is filled with the secondary solvent in advance; and an appropriate pressure is applied to the secondary solvent. Therefore, the entry of a primary solvent into the solvent passage for transferring the secondary solvent is suppressed.Type: GrantFiled: July 24, 2003Date of Patent: July 22, 2008Assignee: KYA Technologies CorporationInventors: Kenichi Kudo, Yoshio Yamauchi
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Publication number: 20080166696Abstract: A method for analyzing proteins according to which two types of samples containing proteins are compared using a mass spectrometer, so that the proteins which are included in respective samples are identified and the mass ratio of a protein of the same type that is included in the respective samples is analyzed, wherein the method for analyzing proteins is characterized by including the steps of: respectively digestting said two types of samples containing proteins at portions of a certain amino acid using a restriction enzyme so as to prepare samples containing peptides; modifying peptides which are included in said respective samples containing peptides with labeling compounds having different masses due to isotopes, so that peptides of the same type that are included in the respective samples containing peptides have different masses; mixing the samples containing peptides that have been respectively labeled with isotopes, separating and quantifying the mixed sample for each peptide and measuring the MS spType: ApplicationFiled: December 17, 2004Publication date: July 10, 2008Inventors: Yoshio Yamauchi, Takashi Shinkawa, Toshiaki Isobe
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Patent number: 6979817Abstract: A problem is to provide a microspray column capable of increasing the ionization efficiency, and a high sensitive mass spectrometer and a mass spectrometric method using such a microspray column. For solving this problem, we provide a column for introducing a sample in an ionization source of a mass spectrometer (ESI/MS) being designed to ionize a sample molecule with electrospray and introduce it into an analyzer, has structural features of: (1) 0.5 ?m or less in an inner diameter of a tip opening of the column; (2) 0.5 ?m or more and 5 ?m or less in a particle size of a column filler; and (3) fritless, a microspray column having the above (1) to (3), a mass spectrometer having such a microspray column in an ionization source, and a mass spectrometric method capable of performing a nonoflow electrospray with the microspray column.Type: GrantFiled: April 8, 2002Date of Patent: December 27, 2005Assignee: Nano Solution, Inc.Inventors: Yoshio Yamauchi, Tohru Natsume, Toshiaki Isobe
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Publication number: 20050129539Abstract: It is an object of the present invention to improve the performance of gradient liquid transfer in nano/micro liquid chromatographs when solvents are mixed. In a gradient liquid transfer device and method for a nano/micro liquid chromatograph, an opening and closing unit (160) capable of opening and closing a solvent passage (150) for transferring a secondary solvent is provided in the vicinity of a solvent mixing section (152) in a liquid transfer system (130); a passage from a metering pump (146) of a liquid transfer section (142) to the opening and closing unit (160) is filled with the secondary solvent in advance; and an appropriate pressure is applied to the secondary solvent. Therefore, the entry of a primary solvent into the solvent passage for transferring the secondary solvent is suppressed.Type: ApplicationFiled: July 24, 2003Publication date: June 16, 2005Inventors: Kenichi Kudo, Yoshio Yamauchi
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Publication number: 20050121608Abstract: A problem is to provide a microspray column capable of increasing the ionization efficiency, and a high sensitive mass spectrometer and a mass spectrometric method using such a microspray column. For solving this problem, we provide a column for introducing a sample in an ionization source of a mass spectrometer (ESI/MS) being designed to ionize a sample molecule with electrospray and introduce it into an analyzer, has structural features of: (1) 0.5 ?m or less in an inner diameter of a tip opening of the column; (2) 0.5 ?m or more and 5 ?m or less in a particle size of a column filler; and (3) fritless, a microspray column having the above (1) to (3), a mass spectrometer having such a microspray column in an ionization source, and a mass spectrometric method capable of performing a nonoflow electrospray with the microspray column.Type: ApplicationFiled: April 8, 2002Publication date: June 9, 2005Applicant: Nano Solution, IncInventors: Yoshio Yamauchi, Tohru Natsume, Toshiaki Isobe
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Publication number: 20050016263Abstract: The present invention aims to provide a liquid chromatograph, an analysis system, and a gradient elution method, which are designed to permit a gradient change of eluent with higher precision and also permit a high sensitive detection or analysis.Type: ApplicationFiled: April 8, 2001Publication date: January 27, 2005Inventors: Yoshio Yamauchi, Tohru Natsume, Toshiaki Isobe
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Patent number: 5180487Abstract: It is an object to provide a recycle chromatograph with supercritical fluid mobile phase for separating a sample into components by recycling a mobile phase which includes modifier solvent for the purpose of taking a desired component.It is structured in such a manner that a recycling pump (10), a column (14), a detector (16), and a three-way valve (18) are connected in a sequential order as described above to form a closed loop which acts as a recycle flow line. A back-pressure regulator (20) is connected to the remainder port (C) of this three-way valve (18), and a mobile phase supplying and pressurizing device (30, 38, 30A, 48) for supplying the mobile phase under a predetermined pressure is connected to a flow line between the three-way valve (18) and the recycling pump (10).By means of this mobile phase supplying and pressurizing device and the recycle closed loop, (the column pressure drop .DELTA.p)/(column plate number) can be reduced, whereupon the column effective plate number can be increased.Type: GrantFiled: June 17, 1991Date of Patent: January 19, 1993Assignee: Nihon Bunko Kogyo Kabushiki KaishaInventors: Muneo Saito, Yoshio Yamauchi
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Patent number: 5013443Abstract: Extraction and separation method and apparatus using a supercritical fluid for extracting a specified component from a sample by a supercritical fluid and introducing the supercritical fluid containing the extracted component into a silica gel column coated with silver nitrate so as to separate the extracted component.By the combination of the extracting operation by a supercritical fluid under mild conditions and chromatography taking the advantage of the selectivity of the silica gel column coated with silver nitrate to olefins, the extract is obtained at a high concentration without producing denaturation.Type: GrantFiled: January 16, 1990Date of Patent: May 7, 1991Assignee: Nihon Bunko Kogyo Kabushiki KaishaInventors: Sakae Higashidate, Yoshio Yamauchi, Muneo Saito