Abstract: An automatic pallet cleaning apparatus for cleaning a pallet which has an object to be cleaned by removing dust deposited thereon. The apparatus includes a conveyance mechanism, an air jet unit and a suction unit. The conveyance mechanism conveys the pallet into a body of the automatic pallet cleaning apparatus. The air jet unit jets air against the pallet conveyed by the conveyance mechanism. The suction unit sucks dust removed from the pallet by the air jet unit.

Abstract: A steel cord for reinforcing automobile tires is composed by intertwisting at least one material wire having small spiral-like curls and 1 to 5 straight material wires. This restricts the ratio of fracture elongation of the two kinds of material wires as well as the elongation percent of the cord at 5 kg loading and improves the stability of twist, the fatigue resistance, the penetrability of a rubber compound and the handling workability.

Abstract: A steel cord comprising a number (between 3 and 27) of element steel wires tightly twisted at a regular pitch P between 5 and 20 mm in the same direction. Each wire has a diameter d between 0.1 and 0.4 mm. At least one of the wires includes a spiral portion having a spiral pitch P1 between 0.1P and 0.7P and a spiral diameter d1 between d+2/100 mm and d+2/10 mm. At least one other wire includes a straight portion. At any cross section of the cord, 1/4 through 2/3 of the wires is/are spiral and the other wire/s is/are straight. The stretch of the cord under a load of 5 kg is between 0.10 and 0.40%. A method of producing a steel cord comprises supplying a number of element steel wires, forming at least part of at least one of the wires to be spiral, and tightly twisting the wires.

Abstract: Fluorine-containing vitamin D.sub.3 analogues of the formula [I]: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen atom, a chemically inactive hydroxy-protecting group, an acyl having 2 to 8 carbon atoms or an alkyl having 1 to 8 carbon atoms, and n is an integer of 4 to 6, which have excellent pharmacological activities, particularly anti-tumor activity owing to differentiation-inducing activity and are useful for the prophylaxis and treatment of various tumors and intermediates therefore.

Abstract: Vitamin D.sub.3 analogues of the formula: ##STR1## wherein R.sup.1 is hydrogen atom and R.sup.2 is hydroxy, or R.sup.1 is hydroxy and R.sup.2 is hydrogen atom, X is hydrogen atom, hydroxy or a hydroxy protected by a hydroxy-protecting group, and R.sup.3 is hydrogen atom or a hydroxy-protecting group, which have vitamin D.sub.3 -like activities such as activity of controlling calcium metabolism and tumor cell differentiation-inducing activity.

Abstract: Fluorine-containing vitamin D.sub.3 analogues of the formula[I]: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen atom, a chemically inactive hydroxy-protecting group, an acyl having 2 to 8 carbon atoms, or an alkyl having 1 to 8 carbon atoms, X is a straight carbon chain having 4 to 6 carbon atoms which contains at least one double or triple bond, which have excellent vitamin D.sub.3 -like activities, particularly anti-tumor activity owing to differentiation-inducing activity and are useful for the prophylaxis and treatment of various tumors, and intermediates therefor.

Abstract: Fluorine-containing vitamin D.sub.3 analogues of the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen atom, a hydroxy-protecting group, having excellent pharmacological activities, such as tumor cell differentiation-inducing activity, which are useful as a medicament.

Abstract: A fluorine-containing vitamin D.sub.2 derivative represented by the following formula ##STR1## wherein R.sup.1 represents a methyl or trifluoromethyl group, and R.sup.2 represents a trifluoromethyl group when R.sup.1 is a methyl group, and a hydrogen atom or a methyl group when R.sup.1 is a trifluoromethyl group. This compound is useful for the prevention or treatment of calcium pathobolism or osteoporosis.

Abstract: A process for preparing human T cell hybridomas which are subculturable and produce lymphokines comprising the steps of: (1) treating a human acute leukemia cell with a protein and/or RNA synthesis inhibitor; (2) independently activating a human T cell with a mitogen or antigen; (3) fusing the thus-treated human acute leukemia cell with the thus-activated human T cell in the presence of a fusion accelerator; and (4) isolating the thus-formed hybridoma. An in vivo process for producing lymphokines using the hybridomas is also described.

Abstract: The invention provides a new derivative of vitamin D.sub.3, 26,26,26,27,27-pentafluoro-1.alpha.-hydroxy-27-methoxy-cholecalciferol and a process for preparing the same.The compound is characterized by some vitamin D-like activity except that it exhibits negligible activity in mobilizing bone. This characteristic indicates that the compound would find ready application in the treatment of disease or physiological states which evince loss of bone mass and application in other situations where metabolic calcium imbalances are found.

Abstract: The invention provides new derivatives of vitamin D.sub.3, 2.alpha.-fluorovitamin D.sub.3 and the acylates thereof.The compounds are characterized by vitamin D-like activity in their ability to increase intestinal calcium transport and serum calcium indicating their ready application as substitutes for vitamin D.

Abstract: A novel compound of 2-[para-(2-substituted or unsubstituted-3,3,3-trifluoropropyl)phenyl]propionic acid or a salt thereof which has a specific pharmacological activity and a pharmaceutical composition comprising the novel compound as an active ingredient are disclosed.

Abstract: The invention provides new derivatives of vitamin D, 23,23-difluoro-25-hydroxycholecalciferol and the acylates thereof, a method for preparing said compounds and various new intermediates utilized in such process.The derivative compounds are characterized by vitamin D-like activity as evidenced by their ability to increase intestinal calcium transport and serum calcium. The compounds are further characterized by resistance to hydroxylation at C-23, which is recognized as an essential metabolic step to the inactivation of vitamin D. The compounds should, therefore, provide vitamin D-like activity of greater time duration.

Abstract: The invention provides new derivatives of vitamin D, 23,23-difluoro-1,25-dihydroxycholecalciferol and the acylates thereof.The derivative compounds are characterized by vitamin D-like activity.

Abstract: The invention provides a new derivative of vitamin D, 23,23-difluoro-1,25-dihydroxycholecalciferol.The compound is characterized by vitamin D-like activity as evidenced by its ability to increase intestinal calcium transport. It is further characterized by its resistance to hydroxylation at C-23, which is recognized as an essential metabolic step to the inactivation of vitamin D, and therefore should provide vitamin D-like activity of greater time duration.

Abstract: The invention provides a new derivative of vitamin D, 23,23-difluoro-25-hydroxycholecalciferol, a method for preparing said compound and various new intermediates utilized in such process.The compound is characterized by vitamin D-like activity as evidenced by its ability to increase intestinal calcium transport and serum calcium. It is further characterized by its resistance to hydroxylation at C-23, which is recognized as an essential metabolic step to the inactivation of vitamin D, and therefore should provide vitamin D-like activity of greater time duration.

Abstract: A novel trifluoropropyl derivative of mono-substituted benzene represented by the general formula: ##STR1## wherein R is halogen atom, hydroxy, trifluoromethyl, n-octyl, n-dodecyl, or phenoxy group not substituted or mono-substituted by 3,3,3-trifluoropropyl group, and n is an integer of 1, 2 or 3, with the proviso that the total number of 3,3,3-trifluoropropyl group of the derivative of mono-substituted benzene is at most 3, and a process for producing the derivative of mono-substituted benzene.

Abstract: A novel trifluoropropyl derivative of mono-substituted benzene represented by the general formula: ##STR1## wherein R is halogen atom, trifluoromethyl, n-octyl, n-dodecyl, or phenoxy group not substituted or mono-substituted by 3,3,3-trifluoropropyl group, and n is an integer of 1, 2 or 3, with the proviso that the total number of 3,3,3-trifluoropropyl group of the derivative of mono-substituted benzene is at most 3, and a process for producing the derivative of mono-substituted benzene.

Abstract: Novel trifluoropropyl-substituted aryl- or aralkylbenzene of the formula: ##STR1## wherein R is a not-substituted or ring-substituted phenyl-, benzyl-, phenethyl- or alpha-methylbenzyl group by one 3,3,3-trifluoropropyl group, and n is an integer of 1,2 or 3, provided that the total number of 3,3,3-trifluoropropyl group of the above-mentioned trifluoropropyl-substituted aryl- or aralkylbenzene is at most 3, and a process for producing thereof are disclosed.

Abstract: This invention provides a new method for preparing 26,26,26,27,27,27-hexafluoro-1,25-dihydroxycholesterol.The method permits the use of cholenic acid or an ester of cholenic acid as the starting material and the preparation of a compound which can be readily converted into a highly active derivative of vitamin D, 26,26,26,27,27,27-hexafluoro-1.alpha.,25-dihydroxycholecalciferol.