Abstract: The present invention provides stable protein solution formulations filled in a container made from a hydrophobic resin at least for the part in direct contact with said formulation.

Abstract: A pre-filled syringe assembly is achieved which prevents, with a strong force, a stopper provided therein from being pulled out, and wherein the stopper can be prevented from being scratched.

Abstract: A longitudinal bag-making, filling and packaging machine, wherein in an outer surface of a product falling and filling tube wrapped by a packaging film folded into a tubular shape by a bag-making device, the packaging film is continuously fed downward by a film feeding device and an edge of the packaging film of which film inner surfaces are superposed on each other in a rib-like fashion is held in a longitudinal sealing device to longitudinally disposition-seal the end edge to form a packaging tube, an article to be packaged supplied through the product falling and filling tube is filled into the packaging tube hung down from the product falling and filling tube and the upper and lower portions of the article to be packaged of the packaging tube are laterally dipositioned-sealed into two strips by a lateral sealing and cutting device and the sealed portion of the two strips is cut.