Abstract: A tissue clipping device and system, and method for clipping tissue are disclosed. The tissue clipping device includes a clip with clip arms that is slidably disposed within a channel of a lock tube. The clip is designed to move between an open configuration in which distal ends of the clip arms are separated from each other for receiving tissue therebetween, and a closed configuration in which the distal ends of the clip arms are closer to each other than in the open configuration for clipping the tissue received therebetween. The tissue clipping system further includes a delivery device for delivering and deploying the tissue clipping device. The delivery device is releasably coupled to the tissue clipping device.

Abstract: An apparatus for insertion into a body through a working channel of an endoscope includes a catheter including a dilator, a guide tube disposed in a lumen of the catheter, and a handle including a puncturing actuator operatively coupled to the proximal end of the guide tube. The dilator may be a cautery device and/or a balloon. The apparatus may also include a stylet needle that includes a cutting distal end for puncturing tissue and extends through a lumen in the guide tube. The handle may further include a stopper detachably coupled to the puncturing actuator to fix a position of the puncturing actuator on the handle, and moveable on the handle independently of the puncturing actuator when detached from the puncturing actuator. The disclosed embodiments also include a method for forming a passageway in a wall of a hollow body organ using the apparatus.

Abstract: A treatment device includes a pipeline having electrical insulation, the pipeline having an internal space through which inert gas passes; a distal-end tip attached to a distal end of the pipeline, the distal-end tip having an opening formed to communicate with the internal space such that the inert gas is disposable from the opening; and an electrode provided in the distal-end tip and configured to be energizable with a high-frequency current. The pipeline includes a proximal-end bending portion with a bending habit, and a distal-end flexible portion without a bending habit that is disposed distal to the proximal-end bending portion.

Abstract: An ablation treatment device for ablating treatment procedure used with endoscope device is disclosed. The ablation treatment device is inserted through the endoscope device and protruded into the human body, where the equipped neutral electrode and a gas channel for injecting inert gas is protruded. Together with another gas channel formed on the endoscope device, two types of gases are injected into the human body together with application of high frequency currents to perform ablation procedure. The ablation treatment device is controlled through a control circuit that administers control of the injection of the gases and application of high frequency currents.

Abstract: A treatment device includes a flexible sheath; a wire configured to be inserted into the sheath; a first treatment member disposed at distal side from the wire; a second treatment member disposed at a distal side from the first treatment member; and a protection member configured to cover the second treatment member when the first treatment member projects from a distal end of the sheath.

Abstract: In a method for treating gastroesophageal reflux disease, an insertion portion of an endoscope is inserted from a cardia into a stomach. A distal end portion can be bent to position a cardiac region and a cautery unit in a field of view of an observation mechanism. The cautery unit can be brought into contact with a first region of a stomach wall around the cardia to cauterize the first region without removing a mucosal layer thereof while the cautery unit and a proximal portion of the insertion portion proximal of the bend are separated from each other by a predetermined distance or more. A position of the cautery unit with respect to the stomach wall can be changed while the separation state is maintained to bring the cautery unit into contact with and cauterize a second region of the stomach wall without removing a mucosal layer thereof.

Abstract: A treatment device includes a flexible sheath; a control wire that can move axially within the flexible sheath; a first treatment member connected to a distal end of the control wire; a second treatment member connected to a distal end of the first treatment member; and a protection member that covers the second treatment member depending on the mode of operation. When the treatment device is in a first treatment mode, the second treatment member projects from a distal end of the protection member. When the treatment device is in a second treatment mode, the first treatment member projects from the distal end of the flexible sheath, and the protection member covers the second treatment member.

Abstract: An apparatus for insertion into a body through a working channel of an endoscope includes a catheter including a dilator, a guide tube disposed in a lumen of the catheter, and a handle including a puncturing actuator operatively coupled to the proximal end of the guide tube. The dilator may be a cautery device and/or a balloon. The apparatus may also include a stylet needle that includes a cutting distal end for puncturing tissue and extends through a lumen in the guide tube. The handle may further include a stopper detachably coupled to the puncturing actuator to fix a position of the puncturing actuator on the handle, and moveable on the handle independently of the puncturing actuator when detached from the puncturing actuator. The disclosed embodiments also include a method for forming a passageway in a wall of a hollow body organ using the apparatus.

Abstract: A treatment device includes a flexible sheath; a control wire that can move axially within the flexible sheath; a first treatment member connected to a distal end of the control wire; a second treatment member connected to a distal end of the first treatment member; and a protection member that covers the second treatment member depending on the mode of operation. When the treatment device is in a first treatment mode, the second treatment member projects from a distal end of the protection member. When the treatment device is in a second treatment mode, the first treatment member projects from the distal end of the flexible sheath, and the protection member covers the second treatment member.

Abstract: A tissue clipping device and system, and method for clipping tissue are disclosed. The tissue clipping device includes a clip with clip arms that is slidably disposed within a channel of a lock tube. The clip is designed to move between an open configuration in which distal ends of the clip arms are separated from each other for receiving tissue therebetween, and a closed configuration in which the distal ends of the clip arms are closer to each other than in the open configuration for clipping the tissue received therebetween. The tissue clipping system further includes a delivery device for delivering and deploying the tissue clipping device. The delivery device is releasably coupled to the tissue clipping device.

Abstract: A treatment tool includes a sheath that has a distal end portion and a proximal end portion, is formed with a lumen through which a guide wire is insertable, and has an opening portion that is opened in a direction intersecting with a central axis of the lumen on an outer circumferential surface of the proximal end portion while communicating with the lumen; a proximal end holding portion that holds a proximal end region at a proximal end side of the proximal end portion; and a distal end holding portion that holds a distal end region disposed more distal than the proximal end region of the proximal end portion, wherein the distal end holding portion holds the distal end region in a bent state with respect to the proximal end region such that the opening portion is located on an extension of the central axis of the lumen.