Patents by Inventor Yoshisuke Nakasato

Yoshisuke Nakasato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemokine receptor antagonists and methods of use therefor
    Patent number: 6503926
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: and physiologically acceptable salts thereof.
    Type: Grant
    Filed: July 28, 1999
    Date of Patent: January 7, 2003
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima, Hiroki Sone, Osamu Kotera, Geraldine C. B. Harriman
  • Chemokine receptor anagonists and methods of use therefor
    Publication number: 20020169155
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation.
    Type: Application
    Filed: November 21, 2001
    Publication date: November 14, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima, Hiroki Sone, Osamu Kotera, Geraldine C.B. Harriman, Kenneth G. Carson
  • CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR
    Publication number: 20020161005
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation.
    Type: Application
    Filed: July 28, 1999
    Publication date: October 31, 2002
    Inventors: JAY R. LULY, YOSHISUKE NAKASATO, ETSUO OHSHIMA, HIROKI SONE, OSAMU KOTERA, GERALDINE C. B. HARRIMAN
  • DERIVATIVES OF BENZOFURAN OR BENZODIOXOLE
    Publication number: 20020128290
    Abstract: An oxygen-containing heterocyclic compound represented by following Formula (I): 1
    Type: Application
    Filed: November 19, 1997
    Publication date: September 12, 2002
    Inventors: ETSUO OHSHIMA, TAKASHI KAWAKITA, KOJI YANAGAWA, KYOICHIRO IIDA, RIE KOIKE, YOSHISUKE NAKASATO, TOHRU MATSUZAKI, KENJI OHMORI, SOICHIRO SATO, HIDEE ISHII, HARUHIKO MANABE, MICHIO ICHIMURA, FUMIO SUZUKI
  • CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR
    Publication number: 20020119973
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation.
    Type: Application
    Filed: July 28, 1999
    Publication date: August 29, 2002
    Inventors: JAY R. LULY, YOSHISUKE NAKASATO, ETSUO OHSHIMA, HIROKI SONE, OSAMU KOTERA, GERALDINE C.B. HARRIMAN
  • Chemokine receptor antagonists and methods of use therefor
    Patent number: 6433165
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula: and physiologically acceptable salts thereof.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: August 13, 2002
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima
  • Chemokine receptor antagonists and methods of use therefor
    Patent number: 6329385
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula: and physiologically acceptable salts thereof.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: December 11, 2001
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima
  • Chemokine receptor antagonists and methods of use therefor
    Patent number: 6288084
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula: and physiologically acceptable salts thereof.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: September 11, 2001
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima
  • Chemokine receptor antagonists and methods of use therefor
    Patent number: 6288083
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by the following structural formula: and physiologically acceptable salts thereof.
    Type: Grant
    Filed: September 4, 1998
    Date of Patent: September 11, 2001
    Assignees: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Jay R. Luly, Yoshisuke Nakasato, Etsuo Ohshima
  • Tetracyclic compound
    Patent number: 5646283
    Abstract: This invention relates to a novel tetracyclic compound represented by formula (I): ##STR1## or its pharmacologically-acceptable salt. The compound of this invention has strong immunosuppressive activity, and is useful as an immunosuppressive agent and as an agent for treating autoimmune disease.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: July 8, 1997
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshisuke Nakasato, Hiroshi Tsumuki, Soichiro Sato, Tadafumi Tamura, Hiroshi Nakajima
  • Pyrazolothiazolopyrimidine derivatives
    Patent number: 5527908
    Abstract: Pyrazolothiazolopyrimidine derivatives represented by the Formula ##STR1## and pharmaceutically acceptable salts thereof are useful as anti-inflammatory, analgesic, immunomodulatory and anti-ulcer agents.
    Type: Grant
    Filed: August 5, 1993
    Date of Patent: June 18, 1996
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshisuke Nakasato, Kenji Ohmori, Tadafumi Tamura, Soichiro Sato, Hiroshi Tanaka
  • Tetracyclic compounds
    Patent number: 5371225
    Abstract: The present invention relates to novel tetracyclic compounds represented by formula (I) ##STR1## (wherein each of X.sup.1 and X.sup.2 independently represents hydrogen or lower alkyl; n represents an integer of 1 to 4), or a pharmaceutically acceptable salt thereof, which are useful as immunosuppressive agents.
    Type: Grant
    Filed: December 22, 1993
    Date of Patent: December 6, 1994
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshisuke Nakasato, Hiroshi Tsumuki, Kenji Ohmori, Hiroshi Nakajima, Tadafumi Tamura, Soichiro Sato
  • Pyrazoloquinoline derivatives
    Patent number: 5192768
    Abstract: A pyrazoloquinoline derivative having the formula (I): ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 independently represent a hydrogen atom or a lower alkyl group; R.sup.4 represents a hydrogen atom, a lower alkyl group, a halogen-substituted lower alkyl group, or a lower alkoxycarbonyl group; the dotted line means that the pyrazole ring has two conjugated double bonds; and R.sup.4 is bonded to the nitrogen atom at the 1-position or 2-position, or pharmacologically acceptable salts thereof. These compounds exhibit excellent anti-inflammatory activity and hepatic insufficiency treating activity.
    Type: Grant
    Filed: September 12, 1991
    Date of Patent: March 9, 1993
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Yoshisuke Nakasato, Kenji Ohmori, Tadafumi Tamura, Hisashi Hosoe, Kazuhiro Kubo, Ikufumi Yoshitake
  • Imidazoquinolone derivatives
    Patent number: 5010084
    Abstract: Novel imidazoquinolone derivative represented by formula (I); ##STR1## wherein R.sup.1 represents lower alkyl or --(CH.sub.2).sub.m CO--R.sup.3 where R.sup.3 represents hydrogen, lower alkyl, hydroxy or lower alkoxy; and m is an integer of 1 to 3; R.sup.2 represents lower alkyl; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 18, 1990
    Date of Patent: April 23, 1991
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Fumio Suzuki, Takeshi Kuroda, Yoshisuke Nakasato, Kenji Ohmori, Haruhiko Manabe