Abstract: A wiring member includes a wiring body and a pattern. The wiring body includes a plurality of wire-like transmission members and a base material. The plurality of wire-like transmission members are fixed to the base material in an aligned state, and the pattern is provided on the wiring body. The pattern makes a two-dimensional position of at least a part of a portion related to the base material recognizable in the wiring body.

Abstract: A method for treating a patient who has a neutralizing antibody to a type A1 botulinum toxin. The method includes administering 150 kDa type A neurotoxin from type A2 Clostridium botulinum (A2 NTX) to the patient. In accordance with the present invention, a problem can be solved of decrease in clinical response caused by a neutralizing antibody to a type A1 botulinum toxin produced when a patient is treated with a pharmaceutical preparation containing a type A1 botulinum toxin.

Abstract: [Object] Provided is a gas barrier film that is substantially uniformly modified in the film thickness direction and exhibits excellent interlayer adhesive force and bending resistance even after being stored under a high temperature and high humidity condition. [Solving Means] Disclosed is a gas barrier film including a plurality of gas barrier layers, the gas barrier film being obtained by coating a coating liquid containing a polysilazane compound on a substrate by simultaneous multilayer coating and drying it to form a plurality of coating layers and then irradiating the plurality of coating layers with vacuum ultraviolet rays from the side of the farthest coating layer from the substrate to conduct a modification treatment, in which at least one layer of the gas barrier layers contains at least one kind of element (however, silicon and carbon are excluded) selected from the group consisting of elements of group 2, group 13, and group 14 in the long form of the periodic table.

Abstract: [Object] Provided is a gas barrier film which exhibits excellent gas barrier property and excellent storage stability in an environment of a high temperature and high humidity condition, particularly adhesive property or folding resistance.

Abstract: A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity.

Abstract: A method for treating a patient who has a neutralizing antibody to a type A1 botulinum toxin. The method includes administering 150 kDa type A neurotoxin from type A2 Clostridium botulinum (A2 NTX) to the patient. In accordance with the present invention, a problem can be solved of decrease in clinical response caused by a neutralizing antibody to a type A1 botulinum toxin produced when a patient is treated with a pharmaceutical preparation containing a type A1 botulinum toxin.

Abstract: A method for quantification of a titer of a neutralizing antibody to a neurotoxin is disclosed. The method comprises the steps: (a) mixing a standard sample containing a fixed amount of a neurotoxin and a test sample containing a neutralizing antibody to said neurotoxin; (b) administering the mixture obtained in step (a) into the muscle of a non-human mammal; (c) applying electric stimulus to said non-human mammal; (d) measuring a compound muscle action potential (CMAP) due to contraction of the muscle of said mammal by application of electric stimulus with an electromyograph; and (e) analyzing CMAP amplitude data obtained in step (d) for an extent of decrease in amplitude by a non-neutralized neurotoxin to thereby quantify a titer of the neutralizing antibody contained in the test sample.

Abstract: A pharmaceutical preparation for use in a patient who has a neutralizing antibody to a botulinum toxin from type A1 Clostridium botulinum (type A1 botulinum toxin), said preparation comprising as an active ingredient 150 kDa type A neurotoxin from type A2 Clostridium botulinum (A2 NTX); a medicament for treating a disease with muscle overactivity for use in a patient who has a neutralizing antibody to a type A1 botulinum toxin, said medicament comprising as an active ingredient said A2 NTX; a method for treating a patient who has a neutralizing antibody to a type A1 botulinum toxin, said method comprising administering said A2 NTX to the patient; and a method for use of A2 NTX in a patient who has said neutralizing antibody. In accordance with the present invention, a problem can be solved of decrease in clinical response caused by a neutralizing antibody to a type A1 botulinum toxin produced when a patient is treated with a pharmaceutical preparation comprising a type A1 botulinum toxin.

Abstract: A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity.

Abstract: A multifocal lens includes a group including M layered lenses. M-kinds (M is an integer of two or more) of lens materials having glass deformation point temperatures of At1, At2, . . . , AtM, are used and diluted by a heat press method. A contact surface of an N?1th lens (N is an arbitrary integer of two or more and M or less) contacted with an Nth lens is a concave face, a contact surface of the Nth lens contacted with the N?1th lens is a convex face. The glass deformation point temperatures have a relation of AtN-1>AtN.

Abstract: An expanded Schrödinger wave equation is discovered that enables one to derive the relativity theory in a direct fashion. Also a method of producing graviton is developed, and gravity is provided as motive power that replaces electromagnetic force. De Broglie's material wave is generated on the basis of the kinetic momentum of an object moving through space. In this connection, one may regard an object at rest as being in motion in a direction of time axis, and may call a new wave motion generated by that motion a “reference wave motion.” Further, by assuming the wavelength of this reference wave motion to be a frame of reference for time and space, one may derive the relativity theory, and then one can find an equation of gravity field obtained from that theory to be a linear equation. Either a gravity wave that satisfies this equation or a graviton obtained by quantizing that gravity wave results from the combining of four different electromagnetic waves.

Abstract: A method for manufacturing a glass optical element having at least one concave surface, including: softening a glass molding material by heating, molding the softened material with a first mold having a first molding surface and a second mold having a second molding surface by applying a pressure, the first molding surface including a first concave forming surface, the second molding surface including a convex forming surface, a planar forming surface or a second concave forming surface, the second concave forming surface having a curvature radius greater than that of the first concave forming surface, whereby the applying of the pressure starts when the first mold and the second mold are at temperatures above a glass transition temperature of said glass molding material, the glass material is cooled so that a temperature of the glass material reaches a temperature equal to or lower than a glass transition temperature (Tg) of the glass material, and the cooled glass material is removed from either of the firs

Abstract: Provided is a method for manufacturing a glass optical element comprising steps of: molding a glass material softened with a molding device which comprises an upper mold having a molding surface and a lower mold having a molding surface so that optically functional surfaces are formed on the glass material by applying a molding pressure, cooling the glass material so that the glass material obtains a predetermined viscosity, and removing the cooled glass material from the molding device, wherein a temperature of the glass material is maintained, in the cooling step, within a range of (Tg+30) to (Tg−50) degree centigrade at least for a predetermined time, and a secondary pressure is applied to the glass material at least during the predetermined time, so that the strain in the glass material is reduced, where Tg represents glass transition temperature of the glass.

Abstract: Provided is a method for manufacturing a glass optical element having at least one concave surface, comprising the following steps: softening a glass molding material by heating, molding the softened material with a first mold having a first molding surface and a second mold having a second molding surface by applying a pressure, the first molding surface comprising a first concave surface, the second molding surface comprising a convex surface, planar surface or second concave surface, the second concave surface having a curvature radius greater than that of said first concave surface, whereby shapes of the first molding surface and the second molding surface are transferred to the material, cooling the material so that a temperature of the material reaches a temperature equal to or lower than glass transition temperature (Tg), and removing the cooled material from either of said first mold or said second mold.

Abstract: Provided is a method for manufacturing a glass optical element comprising steps of: molding a glass material softened with a molding device which comprises an upper mold having a molding surface and a lower mold having a molding surface so that optically functional surfaces are formed on the glass material by applying a molding pressure, cooling the glass material so that the glass material obtains a predetermined viscosity, and removing the cooled glass material from the molding device, wherein a temperature of the glass material is maintained, in the cooling step, within a range of (Tg+30) to (Tg−50) degree centigrade at least for a predetermined time, and a secondary pressure is applied to the glass material at least during the predetermined time, so that the strain in the glass material is reduced, where Tg represents glass transition temperature of the glass.

Abstract: Fluorine-containing polyfunctional (meth)acrylate represented by the formula (1), a monomer composition containing the (meth)acrylate, a low refractivity material prepared by curing the monomer composition, and a reflection reducing film provided with the low refractivity material. wherein R1, R2, R3, and R4 are the same or different groups, and each stands for a hydrogen atom, an acryloyl group, or a methacryloyl group, at least one of R1 and R2 and at least one of R3 and R4 stand for an acryloyl group or a methacryloyl group, R stands for a fluoroalkylene group having 2 to 12 carbon atoms and 2 or more fluorine atoms.

Abstract: Fluorine-containing polyfunctional (meth)acrylate represented by the formula (1), as well as a composition, a low refractivity material and a reflection reducing film in which the (meth)acrylate is utilized: ##STR1## wherein X stands for a fluoroalkyl group of C1-14 having 3 or more F, or a fluorocycloalkyl group of C3-14 having 4 or more F; Y.sup.1, Y.sup.2, and Y.sup.3 stand for H, an acryloyl group or a methacryloyl group, and at least two of Y.sup.1, Y.sup.2, and Y.sup.3 stand for an acryloyl group or a methacryloyl group; Z stands for H or an alkyl group of C1-3; and n and m is an integer of 0 or 1, and n+m=1.

Abstract: A record display medium is provided which can offer a high display contrast and is less likely to cause a lowering of contrast or disappearance of display even in low temperature and high temperature regions. A polymeric material for a liquid crystal/polymer composite film comprising a liquid crystal present in a polymer matrix, a liquid crystal/polymer composite film using the material, and use of the record display medium are also provided. The polymeric material for a liquid crystal/polymer composite film comprising a liquid crystal present in a polymer matrix has a glass transition temperature of 150.degree. C. or above and is insoluble in water.

Abstract: Disclosed is a silver halide photographic light-sensitive material comprising a support having thereon a light-sensitive silver halide emulsion layer and a layer adjacent to said light-sensitive silver halide emulsion layer, whereinat least one of said layers contains a dye having a maximum absorption at a wavelength being within the range of .+-.

Abstract: An image forming material is disclosed which comprises a support and provided thereon, an image forming layer containing colorant particles and a binder, the image forming layer having an optical density of 3.0 or more per 1 .mu.m thickness of the image forming layer at .lambda.max which is a wavelength giving a maximum transparent density in the spectral absorption wavelength range of 350 to 1200 nm of the image forming layer, wherein an image is formed by removing exposed portions of the image forming layer of the image forming material.