Patents by Inventor Yoshitaka Hippo
Yoshitaka Hippo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9644029Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.Type: GrantFiled: December 11, 2014Date of Patent: May 9, 2017Assignees: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahashi, Yasuko Kinoshita
-
Patent number: 9434775Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: GrantFiled: April 1, 2009Date of Patent: September 6, 2016Assignees: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoka Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Patent number: 9376475Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: GrantFiled: August 31, 2010Date of Patent: June 28, 2016Assignees: Perseus Proteomics Inc., Chugai Seiyak Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Publication number: 20150291694Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.Type: ApplicationFiled: December 11, 2014Publication date: October 15, 2015Applicants: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki ABURATANI, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahashi, Yasuko Kinoshita
-
Patent number: 8940488Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.Type: GrantFiled: March 31, 2005Date of Patent: January 27, 2015Assignees: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahshi, Yasuko Kinoshita
-
Publication number: 20110082284Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: ApplicationFiled: August 31, 2010Publication date: April 7, 2011Applicants: ABURANTAI, Hiroyuki, Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Patent number: 7812128Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: GrantFiled: August 26, 2008Date of Patent: October 12, 2010Inventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Patent number: 7691586Abstract: A method for prognosing possible recurrence after treatment of the liver cancer, characterized by measuring GPC3 contained in a test sample by use of an anti-GPC3 antibody.Type: GrantFiled: April 28, 2005Date of Patent: April 6, 2010Assignee: Perseus Proteomics Inc.Inventors: Kiyotaka Watanabe, Shin Ohnishi, Hiroyuki Aburatani, Yutaka Midorikawa, Yoshitaka Hippo, Hiroko Iwanari, Susumu Tokita, Hirokazu Satoh
-
Publication number: 20090226918Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: ApplicationFiled: April 1, 2009Publication date: September 10, 2009Applicants: Perseus Proteomics Inc, Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoka Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Publication number: 20090192108Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: ApplicationFiled: August 26, 2008Publication date: July 30, 2009Applicants: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Publication number: 20080153104Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: ApplicationFiled: August 6, 2004Publication date: June 26, 2008Applicants: HIROYUKI ABURANTAI, PERSEUS PROTEOMICS INC, CHUGAI SEIYAKU KABUSHIKI KAISHAInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong xin Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying qiu Guo, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
-
Publication number: 20080138827Abstract: A method for prognosing possible recurrence after treatment of the liver cancer, characterized by measuring GPC3 contained in a test sample by use of an anti-GPC3 antibody.Type: ApplicationFiled: April 28, 2005Publication date: June 12, 2008Inventors: Kiyotaka Watanabe, Shin Ohnishi, Hiroyuki Aburatani, Yutaka Midorikawa, Yoshitaka Hippo, Hiroko Iwanari, Susumu Tokita, Hirokazu Satoh
-
Publication number: 20070212359Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.Type: ApplicationFiled: March 31, 2005Publication date: September 13, 2007Applicant: Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Yukio Ito, Hirotaka Ito, Shin-ichi Funahashi, Masashi Fukayama, Masahiro Arai, Toshihiko Ohtomo, Yasuko Kinoshita
-
Publication number: 20070037204Abstract: Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.Type: ApplicationFiled: October 20, 2006Publication date: February 15, 2007Applicants: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki KaishaInventors: Hiroyuki Aburatani, Yoshitaka Hippo, Hirokazu Taniguchi, Yong Chen, Shumpei Ishikawa, Shin-ichi Fukumoto, Takahiro Shimamura, Naoko Kamimura, Ying Gou, Shogo Yamamoto, Yukio Ito, Hirotaka Ito, Toshihiko Ohtomo
