Patents by Inventor Yoshitaka Nagahama

Yoshitaka Nagahama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Invertebrate-Derived Gonadotropic Hormone and its Synthesis
    Publication number: 20080096251
    Abstract: The structure of gonadotropic hormone of an invertebrate (Asterina pectinifera) was elucidated. The gonadotropic hormone is a peptide with molecular weight 4500 to 4900 composed of two subunits, wherein the structure of the protein has the structure bound by SS bridges formed between SH residues of cysteines contained in the subunits. Mixing and oxidizing these two subunits after their synthesis enables to give a peptide (gonadotropic hormone) with gonad-stimulating activity.
    Type: Application
    Filed: August 25, 2005
    Publication date: April 24, 2008
    Inventors: Yoshitaka Nagahama, Michiyasu Yoshikuni, Masatoshi Mita, Minoru Isobe
  • Progestogen receptor polypeptides, transgenic cells in which genes encoding said polypeptides are introduced and method for detecting disruptors for progestogens by using said transgenic cells
    Publication number: 20030083487
    Abstract: A polypeptide having an amino acid sequence (a) or (b) given below. (a) a polypeptide having an amino acid sequence shown by amino acid Nos. 1 to 689 in Sequence Listing No. 2 and (b) a polypeptide which has activity of a progestogen receptor and which is a derivative obtained by way of deletion, substitution, addition or insertion of a part of the amino acid sequence in the above (a). Corresponding DNA gene and transgenic cell as well as a method for detecting a disruptor using this transgenic cell are also disclosed.
    Type: Application
    Filed: July 26, 2002
    Publication date: May 1, 2003
    Applicant: OKAZAKI NATIONAL RESEARCH INSTITUTES
    Inventors: Yoshitaka Nagahama, Toshitaka Ikeuchi, Toru Kobayashi, Takashi Todo
  • Transgenic cells and a method for detecting disruptors for androgens by using said transgenic cells
    Publication number: 20030013139
    Abstract: A transgenic cell is disclosed, where includes a culture cell, and an androgen receptor-expression vector and a foreign reporter gene introduced into said culture cell, said foreign reporter gene having a gene promoter, which is a target of said androgen and an androgen receptor, inserted therein. This transgenic cell is used for detecting a disrupter in a material to be examined through examining the expression of the foreign reporter gene when being brought into contact with the material.
    Type: Application
    Filed: June 21, 2002
    Publication date: January 16, 2003
    Applicant: Okazaki National Research Institutes
    Inventors: Yoshitaka Nagahama, Toshitaka Ikeuchi, Toru Kobayashi, Takashi Todo