Abstract: Multimers of human serum albumin are removed from a solution of human serum albumin containing the multimers by bringing the human serum albumin solution into contact with an anion-exchanger equilibrated with a buffer containing a salt in a concentration ranging from 10 to 150 mM and having a pH value ranging from 5 to 9.5.

Abstract: A method for preparing human serum albumin comprises the step of heat-treating a human serum albumin solution containing contaminants at a pH value in the proximity to the isoelectric point of the contaminants.

Abstract: A method for converting a multimer of human serum albumin into monomers thereof comprises the step of treating the multimer with an alkaline solution. This method permits the efficient and quite simple conversion of human serum albumin multimers into monomers thereof at a low cost.

Abstract: Multimers of human serum albumin are removed from a solution of human serum albumin containing the multimers by bringing the human serum albumin solution into contact with an anion-exchanger equilibrated with a buffer containing a salt in a concentration ranging from 10 to 150 mM and having a pH value ranging from 5 to 9.5.

Abstract: A method for preparing human serum albumin comprises the step of heat-treating a human serum albumin solution containing contaminants at a pH value in the proximity to the isoelectric point of the contaminants.

Abstract: In a power transmission belt the outer periphery or the inner periphery of which is covered with a cover fabric, the cover fabric is cylindrically formed of a plurality of fabric pieces joined one to another, one of joint sections of the cover fabric has a lap joint structure that adjacent fabric pieces are lap joined at corresponding ends thereof, and the other one or more joint sections of the cover fabric each have a butt joint structure that adjacent fabric pieces are butt seamed at corresponding ends thereof.

Abstract: The present invention provides a t-PA medicinal preparation obtained by remarkably improving the solubility and stability of t-PA or modified t-PA. Nicotinamide or a derivative thereof is incorporated into t-PA or modified t-PA-containing solvent system. If necessary, a citrate buffer solution is also used. The t-PA-containing medicinal composition is in the form of, for example, a freeze-dried preparation.

Abstract: A top fabric is laminated with an adhesion rubber sheet made of an unvulcanized rubber sheet, which is located on the upper side from a cord of an adhesion rubber layer and forms an upper rubber portion of the adhesion rubber layer, thereby forming a band-shaped laminate. Both longitudinal ends of the band-shaped laminate are butt-jointed with each other so as to produce no level difference at the top surface of the top fabric and at the bottom surface of the adhesion rubber sheet. Thereby, the cord wound around the laminate in the subsequent step is embedded in the adhesion rubber layer without being displaced in level so that the obtained V-ribbed belt produces no abnormal vibration and no noise even if used in serpentine drive.

Abstract: A top fabric 2 which is disposed on the back face of a power transmission belt 1 is obtained by joining a plurality of rubberized fabric pieces 2a, in each of which warps 7 and wefts 8 intersect each other at an obtuse angle which is open toward the direction of the length of the belt, in the shape of a ring. Joining lines of adjacent fabric pieces 2a, 2a both intersect at a right angle with respect to the direction of the length of the belt and are parallel to each other.

Abstract: A top fabric is laminated with an adhesion rubber sheet made of an unvulcanized rubber sheet, which is located on the upper side from a cord of an adhesion rubber layer and forms an upper rubber portion of the adhesion rubber layer, thereby forming a band-shaped laminate. Both longitudinal ends of the band-shaped laminate are butt-jointed with each other so as to produce no level difference at the top surface of the top fabric and at the bottom surface of the adhesion rubber sheet. Thereby, the cord wound around the laminate in the subsequent step is embedded in the adhesion rubber layer without being displaced in level so that the obtained V-ribbed belt produces no abnormal vibration and no noise even if used in serpentine drive.

Abstract: A method and a device for joining rubber sheets. A pressing disk having a shape that a cutting disk is cut at an edge thereof by about 0.7 mm to 1.0 mm joins with pressure edge parts of unvulcanized rubber sheets which are stackably aligned with one another and clamped. The cutting disk cuts the joined edge parts of the rubber sheets. Another pressing disk having a shape that the edge of the cutting disk is cut by about 0.7 mm to 1.0 mm is moved on the cut edge parts along the cutting line in the same manner as the cutting disk, thereby securely joining the joined parts by pressing them again.

Abstract: A plasmid for expression of human coagulation factor VIII H-chain, a plasmid for expression of human coagulation factor VIII L-chain, an animal cell transformed with either said H-chain expression plasmid or said L-chain expression plasmid or with both thereof, and a process for preparing a human coagulation factor VIII protein complex which comprises forming a transformed animal cell by introducing both said H-chain expression plasmid and said L-chain expression plasmid into said animal cell, culturing said cell to produce the human coagulation factor VIII protein complex in the culture medium and collecting the same. The process of the present invention allows for the production of a safe factor VIII at a high expression level applicable for the production of Factor VIII on an industrial scale.

Abstract: An apparatus is provided for manufacturing a fiber reinforced elastic sheet by extruding and processing an elastomer containing staples by 25 volume % or less. The apparatus includes a flow adjustment portion provided in a flow path direction of the elastomer for insuring a uniform flow of the elastomer in a sheet width direction. A weir portion is provided on the downstream side of the flow adjustment portion. A clearance Wo of an outlet in the vertical direction of the sheet, a clearance Wi formed by the weir portion in the vertical direction of the sheet and a distance l between the weir portion and the outlet have the relationship ofWo/Wi.gtoreq.2l.gtoreq.3Wo0.3 mm.ltoreq.Wi.ltoreq.5 MMin order to uniformly orient the staples along the thickness of the sheet.

Abstract: The present invention provides a pipe interior cleaning apparatus which can be operated at an inexpensive cost and with no special facility required, assuring an improved derusting effect. This pipe interior cleaning apparatus comprises a rod-like guide, knobs provided at opposite ends of said guide, and a cleaning member into which said guide is inserted and which is made to be slidable along said guide.

Abstract: A tubular extruder for extruding an elastomeric material mixed with short fibers into a tubular form, with the short fibers circumferentially oriented, a cutter for axially cutting the tubular elastomer, and a development unit for developing the tubular elastomer with a longitudinal slit into a flat form are provided. Arranged between the extruder and the cutter is a guide unit used to guide the tubular elastomer with the help of its tubular section. Air is blown off from the tubular section of the guide unit whereby the tubular elastomer is cooled while at the same time its shrinkage in the circumferential direction is suppressed. The ununiformity of shrinkage is avoidable and the disorientation of short fibers is prevented.

Abstract: A canvas-rubber complex provided on an upper face of a tension rubber on a back side of V-ribbed belt is composed of a covering canvas, impregnation rubber with which the covering canvas is impregnated, an outer rubber layer which is applied to a first face of the covering canvas which is located on the back face's side of the belt, an inner rubber layer which is applied to a second face of the covering canvas which is the back of the first face, and an adhesion rubber layer disposed on a side of the inner rubber layer for adhering the canvas-rubber complex to the upper face of the tension rubber. Among the rubber elements excepting the adhesion rubber layer, at least the outer rubber layer is formed of a rubber composition including as main ingredients thereof CR polymer, hard carbon and conductive carbon.

Abstract: A method for manufacturing a fiber reinforced elastic sheet by extruding and processing an elastomer containing staples by 25 volume % or less. The elastomer, which uniformly flows in a sheet width direction, passes through a slight clearance of a molding die in the vertical direction of the sheet, and then the elastomer flow is enlarged in the vertical direction of the sheet. A flow adjustment portion is provided in a passage of the elastomer to flow uniformly in the sheet width direction, and a weir portion is provided on the downstream side of the flow adjustment portion. A clearance Wo of an outlet in the vertical direction of the sheet, a clearance Wi formed by the weir portion in the vertical direction of the sheet and a distance l between the weir portion and the outlet have the relationship ofWo/Wi.gtoreq.2l.gtoreq.3Wo0.3 mm.ltoreq.Wi.ltoreq.5 mm.