Yoshitaka Tomigahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
Abstract: Abstract There is disclosed a method to measure the fraction of DNA molecules that ishemi-methylated at a specific CpG dinucleotide in a particular DNA sequence, in a pool of DNA molecules having mixed DNA methylation states at said CpG dinucleotide. There is also disclosed methods to calculate the rates of de novo-, and maintenance-methylation per cell division that occur at said CpG dinucleotide. Additionally, there is disclosed methylation kits for use in measuring and quantitating hemi-methylation, and for calculating the rates of de novo-, and maintenance-methylation.
September 25, 2003
April 15, 2004
Peter A. Jones, Gangning Liang, Yoshitaka Tomigahara, Peter W. Laird