Patents by Inventor Yoshitomo Hamuro

Yoshitomo Hamuro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug candidate selection by hydrogen exchange characterization of ligand-induced receptor conformation
    Publication number: 20070093966
    Abstract: A method is provided of selecting a compound that (a) binds a receptor, and (b) on binding the receptor, induces a perturbation in the conformation of the receptor, which conformational perturbation is correlated with a particular pharmacological activity.
    Type: Application
    Filed: July 2, 2004
    Publication date: April 26, 2007
    Applicant: ExSAR CORPORATION
    Inventors: Mark Southern, Yoshitomo Hamuro, Patrick Griffin
  • Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold
    Patent number: 5770380
    Abstract: A synthetic antibody mimic comprising multiple peptide loops built on an organic or molecular scaffold. In a highly preferred embodiment of the invention, a calixarene unit comprises the organic scaffold to which is attached a plurality of peptide loops. The antibody mimics allow for the generation of large libraries of artificial antibodies that can be screened for binding to target antigens.
    Type: Grant
    Filed: September 13, 1996
    Date of Patent: June 23, 1998
    Assignee: University of Pittsburgh
    Inventors: Andrew D. Hamilton, Yoshitomo Hamuro