Patents by Inventor Yoshiyuki ARATA

Yoshiyuki ARATA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for evaluating immunogenicity of test substance
    Patent number: 11733235
    Abstract: In one aspect, disclosed herein is a method for evaluating the immunogenicity of a test substance in a short period of time by using, as an indicator of the immunogenicity of the test substance, the proportion of IL-2-secreting cells in a T cell population (preferably a CD4+ T cell population) at a time point during the early stage of IL-2 secretion after stimulation of the T cell population with the test substance (preferably 24 hours to 72 hours after the stimulation with the test substance).
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: August 22, 2023
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Chiyomi Kubo, Shigeki Motoyama, Yoshiyuki Arata
  • METHOD FOR EVALUATING IMMUNOGENICITY OF TEST SUBSTANCE
    Publication number: 20200191770
    Abstract: The present invention has discovered that the immunogenicity of a test substance can be evaluated in a short period of time by using, as an indicator of the immunogenicity of the test substance, the proportion of IL-2-secreting cells in a T cell population (preferably a CD4+ T cell population) at a time point during the early stage of IL-2 secretion after stimulation of the T cell population with the test substance (preferably 24 hours to 72 hours after the stimulation with the test substance).
    Type: Application
    Filed: December 26, 2017
    Publication date: June 18, 2020
    Inventors: Chiyomi KUBO, Shigeki MOTOYAMA, Yoshiyuki ARATA