Patents by Inventor Yoshiyuki Hotta
Yoshiyuki Hotta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210285975Abstract: The present invention provides a method of testing a blood for a macrolide immunosuppressant conveniently and/or highly accurately. Specifically, the present invention provides a method of testing a blood for a macrolide immunosuppressant, including: (a) treating a blood sample containing a macrolide immunosuppressant or a metabolite thereof having a macrolide structure with an acid or an alkali; and (b) measuring a concentration of the macrolide immunosuppressant or the metabolite in the blood sample by using an antibody.Type: ApplicationFiled: December 19, 2018Publication date: September 16, 2021Applicant: FUJIREBIO INC.Inventors: Masaya TOYONAGA, Yoshiyuki HOTTA
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Patent number: 10423051Abstract: A camera module includes a substrate having a first main surface mounted with an image sensor, a second main surface on the reverse side of the substrate from the first main surface in the predetermined direction, and is provided with at least one hole extending from the first main surface in the predetermined direction. The camera module further includes a holder which has a boss inserted from the first main surface into the at least one hole, and holds at least one lens. The camera module further includes a fixing part made of adhesive that is cured into an anchor shape. The fixing part fixes the boss inside the at least one hole.Type: GrantFiled: April 11, 2018Date of Patent: September 24, 2019Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.Inventors: Hiroyuki Tahara, Takehiro Ueda, Kazuo Sibukawa, Atsuki Kamatani, Yoshiyuki Hotta
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Publication number: 20180231872Abstract: A camera module includes a substrate having a first main surface mounted with an image sensor, a second main surface on the reverse side of the substrate from the first main surface in the predetermined direction, and is provided with at least one hole extending from the first main surface in the predetermined direction. The camera module further includes a holder which has a boss inserted from the first main surface into the at least one hole, and holds at least one lens. The camera module further includes a fixing part made of adhesive that is cured into an anchor shape. The fixing part fixes the boss inside the at least one hole.Type: ApplicationFiled: April 11, 2018Publication date: August 16, 2018Inventors: HIROYUKI TAHARA, TAKEHIRO UEDA, KAZUO SIBUKAWA, ATSUKI KAMATANI, YOSHIYUKI HOTTA
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Patent number: 9410125Abstract: Disclosed are a medium for mammalian somatic cells with which mammalian somatic cells can be grown effectively when the mammalian somatic cells are cultured, while reducing the amount of serum to be added to the medium as much as possible or without adding serum thereto, and an additive to constitute the medium. By blending of a ligand for an endothelial cell differentiation gene (Edg) family receptor and a ligand for a serotonin receptor to a medium, somatic cells of mammals can be grown even in cases where the medium does not contain serum at all or contains only a small amount thereof.Type: GrantFiled: June 14, 2012Date of Patent: August 9, 2016Assignee: FUJIREBIO INC.Inventors: Itsuro Sugimura, Yoshiyuki Hotta, Harumi Yamaguma
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Patent number: 9315777Abstract: Disclosed are a culture medium, an additive, and a method for efficiently inducing the differentiation of mammalian somatic stem cells into cells having the characteristics of bone cells under conditions of serum-free or low-serum culture medium. The culture medium for inducing the differentiation of mammalian somatic stem cells into bone cells comprises a basal medium for culturing mammalian cells, an agent for inducing the differentiation of mammalian somatic stem cells into bone cells, a ligand for endothelial cell differentiation gene (Edg) family receptors and selenium, which culture medium is serum-free or contains a low concentration of serum. The method for inducing differentiation from somatic stem cells into bone cells comprises culturing the somatic stem cells that can differentiate into bone cells in the above-described culture medium.Type: GrantFiled: February 18, 2010Date of Patent: April 19, 2016Assignee: FUJIREBIO INC.Inventor: Yoshiyuki Hotta
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Patent number: 8785199Abstract: Disclosed are a culture medium, an additive, and a method for efficiently inducing the differentiation of mammalian somatic stem cells into cells having the characteristics of adipocytes under conditions of serum-free or low-serum culture medium. The culture medium for inducing the differentiation of mammalian somatic stem cells into adipocytes comprises a basal medium for culturing mammalian cells, an agent for inducing the differentiation of mammalian somatic stem cells into adipocytes, biotin, a ligand for endothelial cell differentiation gene (Edg) family receptors, vitamin C, and HEPES, which culture medium is serum-free or contains a low concentration of serum.Type: GrantFiled: February 18, 2010Date of Patent: July 22, 2014Assignee: Fujirebio, IncInventor: Yoshiyuki Hotta
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Publication number: 20120329155Abstract: Disclosed are a medium for mammalian somatic cells with which mammalian somatic cells can be grown effectively when the mammalian somatic cells are cultured, while reducing the amount of serum to be added to the medium as much as possible or without adding serum thereto, and an additive to constitute the medium. By blending of a ligand for an endothelial cell differentiation gene (Edg) family receptor and a ligand for a serotonin receptor to a medium, somatic cells of mammals can be grown even in cases where the medium does not contain serum at all or contains only a small amount thereof.Type: ApplicationFiled: June 14, 2012Publication date: December 27, 2012Inventors: Itsuro SUGIMURA, Yoshiyuki HOTTA, Harumi YAMAGUMA
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Publication number: 20120178085Abstract: Disclosed are novel means by which evaluation of cultured cells and screening of biomarkers can be attained without consuming the cultured cells. A method for evaluating cultured cells according to the present invention comprises culturing cells in a serum-free medium, and measuring at least one nucleic acid released from the cells into the culture medium. A method for screening of a biomarker according to the present invention comprises culturing cells in a serum-free medium, and measuring a nucleic acid(s) released from the cells into the culture medium. Nucleic acid used as an indicator is e.g. microRNA.Type: ApplicationFiled: June 25, 2010Publication date: July 12, 2012Inventors: Yoshiyuki Hotta, Kazuya Omi, Asako Oka
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Publication number: 20110306133Abstract: Disclosed are a culture medium, an additive, and a method for efficiently inducing the differentiation of mammalian somatic stem cells into cells having the characteristics of adipocytes under conditions of serum-free or low-serum culture medium. The culture medium for inducing the differentiation of mammalian somatic stem cells into adipocytes comprises a basal medium for culturing mammalian cells, an agent for inducing the differentiation of mammalian somatic stem cells into adipocytes, biotin, a ligand for endothelial cell differentiation gene (Edg) family receptors, vitamin C, and HEPES, which culture medium is serum-free or contains a low concentration of serum.Type: ApplicationFiled: February 18, 2010Publication date: December 15, 2011Inventor: Yoshiyuki Hotta
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Publication number: 20110306132Abstract: Disclosed are a culture medium, an additive, and a method for efficiently inducing the differentiation of mammalian somatic stem cells into cells having the characteristics of bone cells under conditions of serum-free or low-serum culture medium. The culture medium for inducing the differentiation of mammalian somatic stem cells into bone cells comprises a basal medium for culturing mammalian cells, an agent for inducing the differentiation of mammalian somatic stem cells into bone cells, a ligand for endothelial cell differentiation gene (Edg) family receptors and selenium, which culture medium is serum-free or contains a low concentration of serum. The method for inducing differentiation from somatic stem cells into bone cells comprises culturing the somatic stem cells that can differentiate into bone cells in the above-described culture medium.Type: ApplicationFiled: February 18, 2010Publication date: December 15, 2011Applicant: FUJIREBIO INC.Inventor: Yoshiyuki Hotta
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Publication number: 20110008893Abstract: Disclosed are a medium for mammalian somatic cells with which mammalian somatic cells can be grown effectively when the mammalian somatic cells are cultured, while reducing the amount of serum to be added to the medium as much as possible or without adding serum thereto, and an additive to constitute the medium. By blending of a ligand for an endothelial cell differentiation gene (Edg) family receptor and a ligand for a serotonin receptor to a medium, somatic cells of mammals can be grown even in cases where the medium does not contain serum at all or contains only a small amount thereof.Type: ApplicationFiled: December 26, 2008Publication date: January 13, 2011Applicant: FUJIREBIO INC.Inventors: Itsuro Sugimura, Yoshiyuki Hotta, Harumi Yamaguma
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Publication number: 20050244824Abstract: A method for measuring a target nucleic acid, which does not require skill and which enables to detect a SNP and to quantify the target nucleic acid simply in a short time is disclosed. In the method of the present invention, the target nucleic acid, a labeled probe which is a labeled nucleic acid which hybridizes with the target nucleic acid, a non-labeled probe which is a nucleic acid having a nucleotide sequence complementary to a region in the target nucleic acid, which region is different from the region with which the labeled probe hybridizes, and an immobilized probe which is a nucleic acid bound to a support, which nucleic acid has a nucleotide sequence complementary to a region in the target nucleic acid, which region is different from the region with which the labeled probe hybridizes are reacted; and the label of the labeled probe bound to the support is measured.Type: ApplicationFiled: March 28, 2003Publication date: November 3, 2005Applicant: FUJIREBIO INC.Inventors: Yoshiyuki Hotta, Ayako Hasegawa, Satoru Ito