Abstract: A medical treatment tool includes an elongated insertion section; a grasper supported by a distal end of the insertion section so as to be openable and closable; a generator disposed at a proximal end of the insertion section and generating a force to drive the grasper; a transmitter transmitting the force generated by the generator to the distal end of the insertion section; an amplifier amplifying the force transmitted through the transmitter; and a toggle amplifying and converting the force amplified by the amplifier into a force directed to open or close the grasper.

Abstract: A medical manipulator includes: an elongated support member; an end effector that is supported at a distal end of the support member so as to be movable in a longitudinal axial direction; a first pulling pulley that is supported so as to be rotatable about a first shaft that is secured to the end effector and that is orthogonal to the longitudinal axis; and a first wire that is wound around the first pulling pulley so as to cause, when a proximal end thereof is pulled, tensile forces in substantially the same directions to act on the first pulling pulley on either side of the first pulling pulley flanking the first shaft.

Abstract: A medical stapler system according to the present invention is equipped with a medical stapler and a staple that closes tissue. The medical stapler is equipped with: a first grasper and a second grasper that have a longitudinal axis and that grasp the tissue therebetween when in a closed state; a holder that retains the staple; a housing body that houses the holder while a needle of the staple projects from a first contact surface of the first grasper; and a drive mechanism that slides the holder along the longitudinal axis. The second grasper has a second contact surface that grasps the tissue between the first contact surface and the second contact surface, a recessed portion that houses the needle without causing penetration or deformation when a closed state, and an anvil against which the needle is pushed and deformed when the closed state.

Abstract: A medical stapler according to the present invention is provided with: a staple housing provided with a gripping surface from which a staple for suturing tissue is ejected, and a cutter that cuts the tissue by being made to protrude from the gripping surface; an anvil that is disposed facing a direction in which the staple is ejected, and that is configured so that the tissue can be gripped between the gripping surface and the anvil; and a receiving member that is provided in the anvil, and that has a receiving surface that receives a cutting edge of the cutter, wherein the receiving surface of the receiving member has a shape in which only a portion thereof comes into contact with the cutting edge of the cutter at individual time points during a cutting step over the entire length of a cut length of the tissue.

Abstract: A medical-treatment-tool according to the present invention is provided with: a inserting-portion; a gripping-piece pivots about a shaft orthogonal to a longitudinal axis of the inserting-portion; a driving-portion generates a motive power with which the gripping-piece is driven; a first motive-power transmitting member transmits the motive power to the inserting-portion; a motive-power amplifying mechanism amplifies the motive power; a pulley secured to the shaft of the gripping-piece; a wire-like second motive-power transmitting member wound around the pulley, transmits amplified the motive power to the pulley, and rotates the pulley about the shaft, thus causing the gripping-piece to be pivoted.

Abstract: A medical treatment tool includes an elongated insertion section; a grasper supported by a distal end of the insertion section so as to be openable and closable; a generator disposed at a proximal end of the insertion section and generating a force to drive the grasper; a transmitter transmitting the force generated by the generator to the distal end of the insertion section; an amplifier amplifying the force transmitted through the transmitter; and a toggle amplifying and converting the force amplified by the amplifier into a force directed to open or close the grasper.

Abstract: A medical stapler system according to the present invention is equipped with a medical stapler and a staple that closes tissue. The medical stapler is equipped with: a first grasper and a second grasper that have a longitudinal axis and that graspe the tissue therebetween when in a closed state; a holder that retains the staple; a housing body that houses the holder while a needle of the staple projects from a first contact surface of the first grasper; and a drive mechanism that slides the holder along the longitudinal axis. The second grasper has a second contact surface that graspes the tissue between the first contact surface and the second contact surface, a recessed portion that houses the needle without causing penetration or deformation when a closed state, and an anvil against which the needle is pushed and deformed when the closed state.

Abstract: A medical manipulator includes: an elongated support member; an end effector that is supported at a distal end of the support member so as to be movable in a longitudinal axial direction; a first pulling pulley that is supported so as to be rotatable about a first shaft that is secured to the end effector and that is orthogonal to the longitudinal axis; and a first wire that is wound around the first pulling pulley so as to cause, when a proximal end thereof is pulled, tensile forces in substantially the same directions to act on the first pulling pulley on either side of the first pulling pulley flanking the first shaft.

Abstract: A surgical-device rotation mechanism according to the present invention includes: a long member; a rotation member rotatably supported by a distal end of the long member and rotates around a longitudinal axis of the long member; an end effector that is fixed to the rotating member; a tension converting member disposed inside the long member along the longitudinal axis and has a distal end to which the rotation member is fixed, and converts tension into rotation around the longitudinal axis; and a rotation restriction mechanism disposed between the long member and the tension converting member and increases or decreases friction between the rotation restriction mechanism and at least one of an inner surface of the long member and an outer surface of the tension converting member so as to restrict or not restrict relative rotation between the long member and the tension converting member around the longitudinal axis.

Abstract: A medical stapler according to the present invention is provided with: a staple housing provided with a gripping surface from which a staple for suturing tissue is ejected, and a cutter that cuts the tissue by being made to protrude from the gripping surface; an anvil that is disposed facing a direction in which the staple is ejected, and that is configured so that the tissue can be gripped between the gripping surface and the anvil; and a receiving member that is provided in the anvil, and that has a receiving surface that receives a cutting edge of the cutter, wherein the receiving surface of the receiving member has a shape in which only a portion thereof comes into contact with the cutting edge of the cutter at individual time points during a cutting step over the entire length of a cut length of the tissue.

Abstract: A medical stapler includes a first and a second grippers that are provided so as to be capable of opening/closing with respect to each other, and that can grip tissue therebetween. The first gripper includes a first contact surface being made to come into firm contact with one side of the tissue, and an ejection hole that is provided in the first contact surface and from which a staple is ejected. The second gripper includes a second contact surface being made to come into firm contact with the other side of the tissue, and an anvil portion provided in the second contact surface and having a curved surface that causes a needle portion of the staple to be bent. The first and second grippers are provided so as to allow relative positions thereof to be adjusted in a tangential direction of the curved surface.

Abstract: A medical stapler including: a first jaw that has a plurality of staples arrayed in a row at intervals; a second jaw that has a second gripping surface that sandwiches living tissue between the second gripping surface and a first gripping surface; and a knife that moves between the first gripping surface and the second gripping surface along the row of staples from the one end of the row to a position extended from the other end of the row of staples, thus cutting the living tissue.

Abstract: A medical staple is provided with: a rectangular base portion; and a needle portion that extends from one end of the base portion in a substantially arc shape so as to protrude in a predetermined direction with respect to the base portion, wherein the needle portion has a first bending position that is provided between a base connected at the one end and a distal end, and that yields first when a pressing force in a radially inward direction of an arc shape of the needle portion acts on the distal end, and a second bending position that is provided between the first bending position and the base, and that yields first when the pressing force acts in the vicinity of the base of the first bending position.

Abstract: An atrial-appendage ligation treatment tool including: a shaft provided with a lumen having, at a distal end thereof, an opening having an opening diameter that allows passage of a thread of a ligation loop formed in a ring shape, which can be tightened, by connecting an end of the thread at an intermediate position by means of a knot and that does not allow passage of the knot; and a cutting part that is provided at a distal end of the shaft and that cuts, at an inner side of the opening and in the vicinity of the opening, the thread passing through the lumen.

Abstract: Completion of atrial-appendage ligation using a ligation loop is confirmed easily and more reliably. Provided is an atrial-appendage ligation treatment tool including: an insertion portion that is introduced into a cardiac sac through a sheath penetrated through a pericardium; a securing part that secures a distal end of the insertion portion to an atrial appendage; and a sensor that is provided at the distal end of the insertion portion and that detects the state of the atrial appendage.

Abstract: Even if atrial-appendage tissue is damaged due to an excessive force unintentionally exerted during ligation of the atrial appendage, the effect of the damage is minimized. Provided is an atrial-appendage ligation treatment tool that is used, together with an atrial-appendage ligation tool having a ligation part, to perform atrial-appendage ligation treatment. The atrial-appendage ligation treatment tool includes: a compressing portion that is introduced, separately from the ligation part, to a cardiac sac through a sheath penetrated through a pericardium and that compresses the atrial appendage from outside to occlude an internal space therein; and a shaft that is disposed in the sheath in an inserted manner and that supports, at a distal end thereof, the compressing portion.

Abstract: This tissue excision device has the following elements: a jaw disposed at a distal end of an insertion portion and used to sandwich tissue; a cutter movable along a track formed along the shape of the jaw; a drive unit which generates force to drive the cutter; and a force transmission member which connects the drive unit and the cutter and accommodated in an accommodation portion provided along the track, and which transmits the force generated by the drive unit to the cutter, and the drive unit is configured to generate greater force as reaction force from the accommodation portion becomes greater.

Abstract: The invention relates to a novel class of self-assembling peptides, compositions thereof, methods for the preparation thereof and methods of use thereof. The invention also encompasses methods for tissue regeneration, increasing the production of extracellular matrix proteins, and methods of treatment comprising administering self-assembling peptides.

Abstract: An atrial-appendage ligation surgical tool that includes a pressing part and a shaft, in which the pressing part is guided into a pericardium via a sheath penetrating through a pericardial membrane, and includes contact portions that press the vicinity of a base of an atrial appendage and have a circular cross-sectional shape and round distal ends, and in which the shaft is in an inserted state in the sheath, supports the pressing part at a distal end, and has a rigidity that enables transmission of a pressing force acting in the longitudinal direction, applied from the proximal end side of the sheath.

Abstract: An atrial appendage ligation surgical tool that includes: a tubular loop shaft having an inner hole that penetrates therethrough in a longitudinal direction; and a ligature loop that is in an inserted state in the inner hole of the loop shaft and formed of a wire that forms a loop closed with a knot at a distal end of the loop shaft, the loop being contractible in size by being pulled from a proximal end of the loop shaft. The ligature loop is given a tendency to form a flat ring-shaped loop having a size an atrial appendage is insertable when in a free state, and the knot is placed near an end of the loop in a long axis direction thereof.