Abstract: An endoscope includes: an insertion pipe line through which a treatment tool is inserted; a suction pipe line; an introduction pipe line into which the treatment tool is introduced; and a branching member that branches the insertion pipe line into the introduction pipe line and the suction pipe line, in which a proximal end portion of the insertion pipe line is inserted into the branching member, the proximal end portion includes a first part and a second part that is provided at a proximal end side with respect to the first part, and an opening facing an introduction pipe line side is formed in an outer peripheral surface of the second part.

Abstract: An operating device for an endoscope includes: a housing that is separable into a plurality of case members; and a suction unit including a suction button, a suction nozzle, and a connecting pipe that connects the suction button and the suction nozzle to each other, in which the plurality of case members include a first case member including a first mounting portion on which the suction unit is mounted, and a second case member which is stuck to the first case member, and the suction unit is partially sandwiched between the first case member and the second case member so that a position of the suction unit in the housing is fixed.

Abstract: A side-viewing endoscope includes an elongated tube for entry in a body cavity for imaging. A wire line is contained in the elongated tube, for moving in an axial direction back and forth. A guide device is coupled with a distal end of the wire line, caused to shift between first and second positions by the wire line, for orientation in a direction crosswise to the axial direction upon being set in the second position. An input lever is disposed at a proximal end of the wire line, for moving the wire line in the axial direction. A cam mechanism is connected between the input lever and the wire line, for shifting the guide device at a first shift between the first position and an intermediate position, and shifting the guide device at a second shift smaller than the first shift between the intermediate and second positions.

Abstract: The endoscope is provided with the forceps elevator which is erectably provided in the distal end part of the insertion part of the endoscope and guides a treatment tool led out from the distal end part. The forceps elevator has an erecting motion range from a minimum angular position to a maximum angular position. If a state in which the treatment tool is not led out from the distal end part is assumed, the erecting operation lever for operating the movement of the forceps elevator has: a first operation range where the erecting operation lever is operated within the erecting motion range of the forceps elevator; and a second operation range where the erecting operation lever is operated beyond the first operation range. When the erecting operation lever is operated into the second operation range, the locking mechanism locks the movement of the erecting operation lever.

Abstract: There is provided an endoscope apparatus which can achieve the improvement of operability with a simple configuration related to the operation of a forceps elevator. The endoscope includes: a forceps elevator which is erectably provided at the distal end part of an operation part that is provided to the insertion part, in an erecting motion range from the minimum angular position to the maximum angular position, and which guides a treatment tool led out from the distal end part; and a locking mechanism which locks the movement of the forceps elevator. An amount of force for locking the movement of the forceps elevator may be varied depending on a direction of that movement and a position of the forceps elevator.

Abstract: There is provided an endoscope apparatus which can achieve the improvement of operability with a simple configuration related to the operation of a forceps elevator. The endoscope includes: a forceps elevator which is erectably provided at the distal end part of an operation part that is provided to the insertion part, in an erecting motion range from the minimum angular position to the maximum angular position, and which guides a treatment tool led out from the distal end part; and a locking mechanism which locks the movement of the forceps elevator. An amount of force for locking the movement of the forceps elevator may be varied depending on a direction of that movement and a position of the forceps elevator.

Abstract: The endoscope is provided with the forceps elevator which is erectably provided in the distal end part of the insertion part of the endoscope and guides a treatment tool led out from the distal end part. The forceps elevator has an erecting motion range from a minimum angular position to a maximum angular position. If a state in which the treatment tool is not led out from the distal end part is assumed, the erecting operation lever for operating the movement of the forceps elevator has: a first operation range where the erecting operation lever is operated within the erecting motion range of the forceps elevator; and a second operation range where the erecting operation lever is operated beyond the first operation range. When the erecting operation lever is operated into the second operation range, the locking mechanism locks the movement of the erecting operation lever.

Abstract: A side-viewing endoscope includes an elongated tube for entry in a body cavity for imaging. A wire line is contained in the elongated tube, for moving in an axial direction back and forth. A guide device is coupled with a distal end of the wire line, caused to shift between first and second positions by the wire line, for orientation in a direction crosswise to the axial direction upon being set in the second position. An input lever is disposed at a proximal end of the wire line, for moving the wire line in the axial direction. A cam mechanism is connected between the input lever and the wire line, for shifting the guide device at a first shift between the first position and an intermediate position, and shifting the guide device at a second shift smaller than the first shift between the intermediate and second positions.

Abstract: A multiple hemostatic clip application apparatus operates for tissue clamping in combination with an endoscope. For use with the clip application apparatus, a clip package is provided, and has a multiple clip assembly, which includes a clip device, and a fastening mechanism, disposed at a proximal end of the clip device, for fastening to a shaft head of an operating wire inserted through a flexible sheath of the clip application apparatus. A coupling device includes a casing for containing the multiple clip assembly in a manner movable from the fastening mechanism toward the flexible sheath, and a guide slider for pressing the shaft head toward the fastening mechanism, for fastening together. The fastening mechanism emerges from the casing, the shaft head being overlapped on the fastening mechanism in an axial direction of the multiple clip assembly.

Abstract: A sensor unit is retained on an assay stage of a surface plasmon resonance (SPR) assay apparatus. The sensor unit includes a prism having a sensing surface, disposed on an upper surface thereof, for detecting reaction of a sample. A flow cell is secured to the upper surface, and has a flow channel for flow of sample fluid containing the sample to the sensing surface. The sensor unit is set removably on the assay apparatus for optically measuring reaction of the sample. In sensor holding, the sensor unit is set on a stage surface of the assay stage by directing down the prism. In a pushing step, a lower surface of the prism is pushed on the stage surface in a first direction upright relative to the stage surface. Two holders push an upper face of the first and second ridges of the prism in the first direction.

Abstract: A clip package comprises: a clip assembly including at least one endoscopic clip and at least one connection ring connected to the clip, the connection ring having at least one skirt portion that is allowed to expand radially outwards and stick out when in natural state free from external force and closes inwards when depressed radially inwards, a cylindrical case including an accommodation section for accommodating the clip assembly, the cylindrical case further including at least one opening in a position corresponding to the skirt portion of the connection ring, the opening being provided to maintain the skirt portion in natural state, and a cylindrical outer tube movably fitted over the outer periphery of the case and including at least one skirt closer for depressing and inwardly closing the skirt portion when the skirt closer is moved to a position opposite the opening.

Abstract: A multiple hemostatic clip application apparatus operates for tissue clamping in combination with an endoscope. For use with the clip application apparatus, a clip package is provided, and has a multiple clip assembly, which includes a clip device, and a fastening mechanism, disposed at a proximal end of the clip device, for fastening to a shaft head of an operating wire inserted through a flexible sheath of the clip application apparatus. A coupling device includes a casing for containing the multiple clip assembly in a manner movable from the fastening mechanism toward the flexible sheath, and a guide slider for pressing the shaft head toward the fastening mechanism, for fastening together. The fastening mechanism emerges from the casing, the shaft head being overlapped on the fastening mechanism in an axial direction of the multiple clip assembly.

Abstract: A multiple hemostatic clip application apparatus includes a multiple clip assembly and a flexible sheath coupled with the multiple clip assembly, and operates for tissue clamping in combination with an endoscope. For the clip coupling, a pull rod structure is pulled to introduce the multiple clip assembly into a fin bending channel in a housing. Fins of the multiple clip assembly are depressed and stowed by the inside of the fin bending channel. The housing is removed from a coupling device. An operating wire is fastened to a fastening clip device. The flexible sheath is inserted in an access hole to register the inside of the flexible sheath with the fin bending channel. When the operating wire is pulled relative to the flexible sheath, the multiple clip assembly is introduced into the flexible sheath.

Abstract: A multiple clip device for hemostatic clamping of a lesion of a patient's body includes plural clips fastened to one another in a train, having first and second clips, a proximal end portion of the first clip being engaged with two claws of a distal end portion of the second clip. A dummy clip has claws in a shape of the claws of the clips, and is engaged with a proximal end portion of a final clip among the clips by the claws thereof. An end connector is for retention of the dummy clip, and for fastening in a removable manner to a shaft head at an end of an operating wire inserted in a flexible sheath of a multiple clip application apparatus. Specifically, the multiple clip application apparatus is constituted by the operating wire and the multiple clip device fastened thereto.

Abstract: A surface plasmon resonance (SPR) assay apparatus has an assay stage, which is loadable with a sensor unit. The sensor unit has a prism, thin film, flow cell and flow channel for flow of sample. A multiple pipette assembly accesses the flow channel in the assay stage, and introduces the sample into the flow channel. A light source applies illuminating light to the thin film to satisfy a total reflection condition. A photo detector receives the illuminating light reflected by the thin film to output a signal. A pressing mechanism presses the sensor unit on the assay stage for holding in a direction of the access of the pipette assembly. The pressing mechanism includes a movable pad for contacting the sensor unit. A slider moves the pad to press the sensor unit. A spring plunger adjusts pressure of the pad to the sensor unit.

Abstract: A sensor unit includes a dielectric block, a thin film layer and a reference surface. The thin film layer is formed on the upper surface of the dielectric block and the reference surface is coplanar with the upper surface of the dielectric block. The sensor unit is held in a predetermined position. A light beam is caused to enter the dielectric block to impinge upon the interface between the upper surface of the dielectric block and the thin film layer so that total internal reflection conditions are satisfied at the interface. Information on an analyte on the thin film layer is obtained on the basis of the light beam reflected at the interface. Displacement of the interface is measured by measuring displacement of the reference surface and the position of the sensor unit is adjusted according to the displacement of the reference surface.

Abstract: A sensor unit is retained on an assay stage of a surface plasmon resonance (SPR) assay apparatus. The sensor unit includes a prism having a sensing surface, disposed on an upper surface thereof, for detecting reaction of a sample. A flow cell is secured to the upper surface, and has a flow channel for flow of sample fluid containing the sample to the sensing surface. The sensor unit is set removably on the assay apparatus for optically measuring reaction of the sample. In sensor holding, the sensor unit is set on a stage surface of the assay stage by directing down the prism. In a pushing step, a lower surface of the prism is pushed on the stage surface in a first direction upright relative to the stage surface. Two holders push an upper face of the first and second ridges of the prism in the first direction.