Abstract: A compound having GSK-3 inhibitory activity. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is H, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl, or cyano group when A6 is CR?CR or C?C, wherein R is H or an lower aliphatic hydrocarbon group.

Abstract: The present invention is a thiobenzimidazole derivative represented by the following formula (1) or a medically acceptable salt thereof wherein said thiobenzimidazole derivative and a medically acceptable salt thereof have a potent activity of inhibiting human chymase. Thus, they are potential preventive and/or therapeutic agents clinically applicable to various diseases in which human chymase is involved.

Abstract: The present invention is a thiobenzimidazole derivative represented by the following formula (1) or a medically acceptable salt thereof wherein said thiobenzimidazole derivative and a medically acceptable salt thereof have a potent activity of inhibiting human chymase. Thus, they are potential preventive and/or therapeutic agents clinically applicable to various diseases in which human chymase is involved.

Abstract: It is aimed at providing a data processor capable of suppressing a sudden current change from the viewpoint of a synchronization clock. A data processor 1 comprises a clock pulse generation circuit and a circuit module operating on input clock signal CLKi output from the clock pulse generation circuit. In case of restoration from a power-on reset period or a standby state, the clock pulse generation circuit stepwise changes frequencies of the clock signal from low to high frequencies. This makes it possible to prevent a power supply current from suddenly increasing in case of restoration from the power-on reset period or the standby state.

Abstract: The system LSI has a MCU, a memory access control means equipped with unified memory interfaces with which at least two lines of unified memories A and B can be connected. In the main unit of the data processing system, the purpose of each unified memory is set like “mainly for main storage” or “mainly for display” by software in accordance with the operating status of the data processing system so as to adjust the memory access performance. In addition, the system has a means for specifying the unified memory to access and area therein for every display plane to be controlled by the display control circuit.

Abstract: A diesel engine control system and control method capable of conducting accurate fuel injection unaffected by variations in injector performance caused by differences among individual injectors or change with aging. The diesel engine control system includes an injector for directly injecting fuel into a combustion chamber of a diesel engine, injection quantity controller for controlling fuel injection quantity by varying a period of electric current supply to the injector, estimator for estimating that an electric current supply period when a prescribed (stable) combustion state is obtained is the current supply period for injecting the amount of fuel required for the prescribed combustion state, and control data correcting device for correcting control data of the injection quantity controller based on the estimated current supply period.

Abstract: According to the invention, an EGR control apparatus of an engine includes intake ports to which an intake passage is connected, the intake ports opening into each combustion chamber of the engine, an EGR port to which an EGR passage branching out from an exhaust passage is connected, the EGR port opening into each combustion chamber of the engine, an electrically-operated compressor disposed in the EGR passage for regulating pressure at which EGR gas is introduced into each combustion chamber, and an EGR control valve disposed in the EGR passage at a point downstream of the electrically-operated compressor for controlling the amount of EGR gas introduced into each combustion chamber. The EGR passage branches out from the exhaust passage at a point downstream of an emission control device disposed in the exhaust passage.

Abstract: A compound having GSK-3 inhibiting function. A1 and A3 are a single bond, an aliphatic hydrocarbon group; A2 and A4 are a single bond, CO, COO, CONR, O, OCO, NR, NRCO, NRCOO, etc.; G1 is a single bond, an aliphatic hydrocarbon, aromatic hydrocarbon, heterocyclic; G2 is a hydrogen atom, an aliphatic hydrocarbon, an alicyclic hydrocarbon, an aromatic hydrocarbon, heterocyclic; A5 is a single bond, NR; R2 is H, halogen, an aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; A6 is a single bond, NR, CO, NRCO, NRCONR, CONR, COO, O, etc.; R3 is H, halogen, nitro, saturated aliphatic hydrocarbon, alicyclic hydrocarbon, aromatic hydrocarbon, heterocyclic; and when A6 is CR?CR or C?C; R3 may be a trimethylsilyl, formyl, acyl, carboxyl, alkoxylcarbonyl, carbamoyl, alkylcarbamoyl or cyano group; and R is H or an aliphatic hydrocarbon group.

Abstract: According to the invention, an EGR control apparatus of an engine includes intake ports to which an intake passage is connected, the intake ports opening into each combustion chamber of the engine, an EGR port to which an EGR passage branching out from an exhaust passage is connected, the EGR port opening into each combustion chamber of the engine, an electrically-operated compressor disposed in the EGR passage for regulating pressure at which EGR gas is introduced into each combustion chamber, and an EGR control valve disposed in the EGR passage at a point downstream of the electrically-operated compressor for controlling the amount of EGR gas introduced into each combustion chamber. The EGR passage branches out from the exhaust passage at a point downstream of an emission control device disposed in the exhaust passage.

Abstract: A benzimidazole derivative or its medically acceptable salt, represented by the following formula (1), that is a human chymase activity inhibitor capable of being applied clinically: 1

Abstract: A benzimidazole derivative or its medically acceptable salt, represented by the following formula (1), that is a human chymase activity inhibitor capable of being applied clinically: 1

Abstract: The present invention provides a benzimidazole derivative or its. pharmaceutically permissible salt expressed by the following formula (1). Further, the present invention provides a human chymase activity inhibitor containing the substance as an active ingredient.

Abstract: A vehicle travel aiding device for sensing running conditions of the vehicle and outputting vehicle travel supporting information, which is featured by detecting ambient circumstances and road conditions on which the vehicle is and operating driver's brake operation response on accelerator release response and changing the outputting timing or the content of the supporting information according to the detection results.

Abstract: A speech input control device for recognizing an input speech and giving a specified control instruction to a target device, which device is provided with a portion for detecting that a word inputted by voice is unregistered in a voice word dictionary, a portion for extracting a feature of the detected unregistered words and storing the extracted feature, a portion for counting the input frequency of each unregistered word and renewably storing the counted input frequency, and a portion for changing a response message in response to an unregistered word depending to its input frequency and which is capable of adaptively responding by avoiding outputting the same response message such as "The input cannot be recognized" and "Correct input is required" or the like whenever the user's meaningless word or habitual phrase is inputted thereafter.

Abstract: An optical pickup device for irradiating a laser beam onto an optical recording medium and receiving a return light from the optical recording medium, comprising a semiconductor laser element which is formed on a semiconductor substrate and has first and second light emitting faces, a first reflection portion provided so as to confront the first light emitting face of the semiconductor laser element, a second reflection portion provided so as to provide confront the second light emitting face of the semiconductor laser element, a first photodetector for receiving a return reflection light of the laser beam which is reflected from the first reflection portion and focused on the recording medium, and a second photodetector for receiving a return reflection light of the laser beam which is reflected from the second reflection portion and focused on the recording medium. A recording signal on the recording medium and a focus error signal are detected by the first and second photodetectors.

Abstract: A warning system for a vehicle has a warning device for issuing a warning when the vehicle approaches an object. A warning timing parameter section detects a driving operation by the driver of the vehicle, and calculates a reaction time from the time a warning is issued by the warning device to the time the driver starts the driving operation in response to the warning. A warning control section controls the timing at which the warning should be issued by the warning device, based on the calculated reaction time.

Abstract: A magneto-optical head apparatus of a recording and/or reproducing apparatus includes a light beam generating unit, an objective lens, a separating optical element, a reflecting mirror, and a photodetector. The objective lens converges a light beam emitted from the light beam generating unit on a point on an optical axis, e.g., a point on the recording layer of a magneto-optical recording medium. The separating optical element deflects the light beam emitted from the light beam generating unit, and separates the light beam emitted from the light beam generating unit and a light beam through the objective lens. The reflecting mirror deflects the light beam emitted from the light beam generating unit and deflected by the separating optical element at 90.degree. so that the light beam is led to the objective lens. The photodetector receives the light beam irradiating through the objective lens and passing through the separating optical element.

Abstract: Disclosed is a vehicle travel guiding apparatus for searching a course having the least cost of line segments between a start and a target points preset on a road map indicated on a display screen according to digitized map data, wherein when a plurality of courses are searched one by one by priority of smaller cost of line segments' for the purpose of selecting an optimal course with due consideration of traffic conditions, the segments' cost of the last searched course is apparently increased before searching next one so as to eliminate the possibility of selecting the like course again.

Abstract: A wheel support structure of a motor vehicle wherein a double angular bearing 11 is constituted of an outer race 12 integrally installed in one of such members as a hub 9 on which a wheel is mounted and a knuckle 3 to which a suspension arm is installed, inner races 14a and 14b installed in the other, and double rows of balls 13a and 13b inserted between the races; and a lock nut 15 is tightened to compress the inner races 14a and 14b in an axial direction. There is formed a clearance between the inner races 14a and 14b in a no-load condition. The bearing thus constituted is provided with a large rigidity to thereby improve the steering stability of the motor vehicle.

Abstract: Disclosed is a vehicle travelling searching apparatus for finding an optimal course between two points preset on a road map by searching optimal partial course components on the basis of digitized road map data by use of a synthetically evaluating function including a plurality of travelling-cost-related variable parameters, changing over weight coefficients of the parameters or the function itself to adequate coefficients or function for each partial searching condition.