Patents by Inventor Yoshiyuki Muranaka

Yoshiyuki Muranaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfated polysaccharide, pharmaceutically acceptable salt thereof, process for preparing same and medicament containing same as effective component
    Patent number: 5519010
    Abstract: The present invention provides a sulfated polysaccharide (D-HG), a pharmaceutically acceptable salt thereof, a process for preparing the same and a medicament containing the same as the effective component for DIC (disseminated intravascular coagulation) and thrombosis, the sulfated polysaccharide (D-HG) being prepared by depolymerization of FGAG (a sulfated polysaccharide extracted from a body wall of a sea cucumber with such activities as those of heparin) or a salt thereof and having the following physicochemical properties:[1] Molecular weight:3,000 to 42,000 (as measured by high performance GPC)[2] Characteristic:white, amorphous, highly hygroscopic powder[3] Solubility:soluble in water but insoluble in ethanol, acetone and like organic solvents[4] Specific rotation:[.alpha.].sub.D.sup.20 =-55 to -73.degree.
    Type: Grant
    Filed: May 12, 1994
    Date of Patent: May 21, 1996
    Assignees: Taiho Pharmaceutical Co., Ltd., Kotai Kasei Co., Ltd.
    Inventors: Hui-Zeng Fan, Song Yu, Etsuji Yamanaka, Kazuhiro Numata, Toshinori Oka, Norihiko Suzuki, Yoshiyuki Muranaka
  • Sulfonic acid ester derivatives and process for preparing same
    Patent number: 4797502
    Abstract: A sulfonic acid ester derivative represented by the general formula ##STR1## wherein R.sub.1 is a hydrogen atom, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms, A is a group represented by the general formula ##STR2## (wherein R.sub.2 and R.sub.3 are each alkyl having 1 to 4 carbon atoms) or by the general formula ##STR3## (wherein R.sub.4 and R.sub.5 are each alkyl having 1 to 4 carbon atoms or, when taken together with the carbon atom to which they are attached, form cycloalkyl having 4 to 6 carbon atoms), and l is an integer of from 1 to 3, and a process for preparing the derivative.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: January 10, 1989
    Assignee: Taiho Pharmaceutical Company Limited
    Inventors: Setsuro Fujii, Kazuo Ogawa, Toshihiro Hamakawa, Yoshiyuki Muranaka
  • Sulfonic acid ester derivatives useful as antilipemic agents
    Patent number: 4675428
    Abstract: A sulfonic acid ester derivative represented by the general formula ##STR1## wherein R.sub.1 is a hydrogen atom, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms, A is a group represented by the general formula ##STR2## (wherein R.sub.2 and R.sub.3 are each alkyl having 1 to 4 carbon atoms) or by the general formula ##STR3## (wherein R.sub.4 and R.sub.5 are each alkyl having 1 to 4 carbon atoms or, when taken together with the cabon atom to which they are attached, form cycloalkyl having 4 to 6 carbon atoms), and l is an integer of from 1 to 3, and a process for preparing the derivative.
    Type: Grant
    Filed: May 7, 1986
    Date of Patent: June 23, 1987
    Assignee: Taiho Pharmaceutical Company, Limited
    Inventors: Setsuro Fujii, Kazuo Ogawa, Toshihiro Hamakawa, Yoshiyuki Muranaka
  • Antilipemic and anti-inflammatory compositions containing sulfonate derivatives
    Patent number: 4489091
    Abstract: Novel sulfonate derivatives represented by the formulaR.sub.1 SO.sub.3 CH.sub.2 CO(CH.sub.2).sub.n R.sub.2act to inhibit esterases and chymotripsin and are useful as antilipemic agents, anti-inflammatory agents, immunity controlling agents, etc.
    Type: Grant
    Filed: May 9, 1983
    Date of Patent: December 18, 1984
    Assignee: Taiho Pharmaceutical Company Limited
    Inventors: Setsuro Fujii, Toshihiro Hamakawa, Kazuo Ogawa, Yoshiyuki Muranaka, Sadao Hashimoto
  • Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
    Patent number: 4452813
    Abstract: A sulfonate derivative represented by the formula ##STR1## wherein R.sub.1 is lower alkyl, lower alkoxy or halogen, l is an integer of from 0 to 3, n is 0 or 1, A is straight-chain or branched-chain alkylene having 1 to 4 carbon atoms, and R.sub.2 is hydrogen or lower alkyl but, when n is 0 or 1 and A is straight-chain alkylene with 1 to 4 carbon atoms, is not hydrogen and the method for preparing the same.
    Type: Grant
    Filed: May 11, 1982
    Date of Patent: June 5, 1984
    Assignee: Taiho Pharmaceutical Company Limited
    Inventors: Setsuro Fujii, Toshihiro Hamakawa, Kazuo Ogawa, Yoshiyuki Muranaka, Sadao Hashimoto
  • Method of treating hyperlipidemia and inflammation with sulfonate derivatives
    Patent number: 4411911
    Abstract: Novel sulfonate derivatives represented by the formulaR.sub.1 SO.sub.3 CH.sub.2 CO(CH.sub.2).sub.n R.sub.2act to inhibit esterases and chymotripsin and are useful as antilipemic agents, anti-inflammatory agents, immunity controlling agents, etc.
    Type: Grant
    Filed: January 19, 1981
    Date of Patent: October 25, 1983
    Assignee: Taiho Pharmaceutical Company, Limited
    Inventors: Setsuro Fujii, Toshihiro Hamakawa, Kazuo Ogawa, Yoshiyuki Muranaka, Sadao Hashimoto