Patents by Inventor Yoshiyuki Okishima

Yoshiyuki Okishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8142635
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: March 27, 2012
    Assignee: Hitachi, Ltd.
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Publication number: 20100288642
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Application
    Filed: July 26, 2010
    Publication date: November 18, 2010
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Patent number: 7785458
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: August 31, 2010
    Assignee: Hitachi, Ltd.
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Patent number: 7540949
    Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.
    Type: Grant
    Filed: July 26, 2005
    Date of Patent: June 2, 2009
    Assignee: Hitachi, Ltd.
    Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
  • Patent number: 7473342
    Abstract: In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.
    Type: Grant
    Filed: April 3, 2006
    Date of Patent: January 6, 2009
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Seiichi Ugai, Tomonari Morioka, Ryoji Inaba, Akihiro Suzuki, Yoshinori Ookoshi, Yoshiyuki Okishima, Tsukasa Ohira, Motohiro Yamazaki, Takashi Gomi
  • Publication number: 20060219559
    Abstract: In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.
    Type: Application
    Filed: April 3, 2006
    Publication date: October 5, 2006
    Inventors: Seiichi Ugai, Tomonari Morioka, Ryoji Inaba, Akihiro Suzuki, Yoshinori Ookoshi, Yoshiyuki Okishima, Tsukasa Ohira, Motohiro Yamazaki, Takashi Gomi
  • Patent number: 7081191
    Abstract: The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulling up the syringe plunger on a push-in action type syringe (125). A check valve (124) is inserted between a polymer bottle (123) and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: July 25, 2006
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Tomihiro Shoji, Masaya Kojima, Yoshiyuki Okishima, Ryoji Inaba
  • Publication number: 20060091012
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Application
    Filed: December 15, 2005
    Publication date: May 4, 2006
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Patent number: 7005052
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: February 28, 2006
    Assignee: Hitachi, Ltd.
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Publication number: 20060000714
    Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.
    Type: Application
    Filed: July 26, 2005
    Publication date: January 5, 2006
    Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
  • Patent number: 6936152
    Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: August 30, 2005
    Assignee: Hitachi, Ltd.
    Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
  • Patent number: 6881316
    Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes. According to the present invention, a connection plate 23 and hollow electrodes 20 are connected without solder but via a spring force. Alternatively, the hollow electrodes 20 can be connected to the connection plate 23 by utilizing volume elasticity of the connection plate.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: April 19, 2005
    Assignee: Hitachi, Ltd.
    Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
  • Patent number: 6878256
    Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes. According to the present invention, a connection plate 23 and hollow electrodes 20 are connected without solder but via a spring force. Alternatively, the hollow electrodes 20 can be connected to the connection plate 23 by utilizing volume elasticity of the connection plate.
    Type: Grant
    Filed: March 19, 2002
    Date of Patent: April 12, 2005
    Assignee: Hitachi, Ltd.
    Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
  • Publication number: 20040003994
    Abstract: The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulling up the syringe plunger on a push-in action type syringe (125). A check valve (124) is inserted between a polymer bottle (123) and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.
    Type: Application
    Filed: September 20, 2002
    Publication date: January 8, 2004
    Inventors: Tomihiro Shoji, Masaya Kojima, Yoshiyuki Okishima, Ryijo Inaba
  • Patent number: 6660148
    Abstract: An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is inserted between the both syringes, and the check valve 16 works so as to prevent the gel 10 from flowing back to the charging syringe 15. As the result, the gel charging can be automated, and accordingly the processing ability of the electrophoretic instrument can be improved.
    Type: Grant
    Filed: February 26, 2001
    Date of Patent: December 9, 2003
    Assignee: Hitachi, Ltd.
    Inventors: Tomohiro Shoji, Yoshiyuki Okishima, Masaya Kojima, Muneo Maeshima
  • Publication number: 20020179446
    Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes.
    Type: Application
    Filed: July 9, 2002
    Publication date: December 5, 2002
    Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
  • Publication number: 20020139672
    Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes.
    Type: Application
    Filed: March 19, 2002
    Publication date: October 3, 2002
    Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
  • Publication number: 20020003091
    Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.
    Type: Application
    Filed: May 10, 2001
    Publication date: January 10, 2002
    Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
  • Publication number: 20010040095
    Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.
    Type: Application
    Filed: May 1, 2001
    Publication date: November 15, 2001
    Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
  • Publication number: 20010017263
    Abstract: An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is inserted between the both syringes, and the check valve 16 works so as to prevent the gel 10 from flowing back to the charging syringe 15. As the result, the gel charging can be automated, and accordingly the processing ability of the electrophoretic instrument can be improved.
    Type: Application
    Filed: February 26, 2001
    Publication date: August 30, 2001
    Inventors: Tomohiro Shoji, Yoshiyuki Okishima, Masaya Kojima, Muneo Maeshima