Patents by Inventor Yoshiyuki Okishima
Yoshiyuki Okishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8142635Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: GrantFiled: July 26, 2010Date of Patent: March 27, 2012Assignee: Hitachi, Ltd.Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Publication number: 20100288642Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: ApplicationFiled: July 26, 2010Publication date: November 18, 2010Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Patent number: 7785458Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: GrantFiled: December 15, 2005Date of Patent: August 31, 2010Assignee: Hitachi, Ltd.Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Patent number: 7540949Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.Type: GrantFiled: July 26, 2005Date of Patent: June 2, 2009Assignee: Hitachi, Ltd.Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
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Patent number: 7473342Abstract: In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.Type: GrantFiled: April 3, 2006Date of Patent: January 6, 2009Assignee: Hitachi High-Technologies CorporationInventors: Seiichi Ugai, Tomonari Morioka, Ryoji Inaba, Akihiro Suzuki, Yoshinori Ookoshi, Yoshiyuki Okishima, Tsukasa Ohira, Motohiro Yamazaki, Takashi Gomi
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Publication number: 20060219559Abstract: In a case where the temperature of capillaries cannot be controlled rapidly in accordance with the change of the amount of heat generated from the capillaries, the phoretic speed of the sample is not controlled constant to lower the analyzing performance for the sample. This invention intends to stabilize the electrophoretic speed. The surface of a substrate on which a plurality of capillaries are arranged is in contact with a member capable of temperature control thereby controlling the temperature of the capillaries. Since a member capable of controlling the temperature and the capillaries are in direct contact with each other according to the invention, the temperature of the capillary can be controlled rapidly at a high accuracy, so that electrophoretic speed is stabilized.Type: ApplicationFiled: April 3, 2006Publication date: October 5, 2006Inventors: Seiichi Ugai, Tomonari Morioka, Ryoji Inaba, Akihiro Suzuki, Yoshinori Ookoshi, Yoshiyuki Okishima, Tsukasa Ohira, Motohiro Yamazaki, Takashi Gomi
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Patent number: 7081191Abstract: The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulling up the syringe plunger on a push-in action type syringe (125). A check valve (124) is inserted between a polymer bottle (123) and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.Type: GrantFiled: January 18, 2002Date of Patent: July 25, 2006Assignee: Hitachi High-Technologies CorporationInventors: Tomihiro Shoji, Masaya Kojima, Yoshiyuki Okishima, Ryoji Inaba
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Publication number: 20060091012Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: ApplicationFiled: December 15, 2005Publication date: May 4, 2006Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Patent number: 7005052Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: GrantFiled: May 1, 2001Date of Patent: February 28, 2006Assignee: Hitachi, Ltd.Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Publication number: 20060000714Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.Type: ApplicationFiled: July 26, 2005Publication date: January 5, 2006Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
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Patent number: 6936152Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.Type: GrantFiled: May 10, 2001Date of Patent: August 30, 2005Assignee: Hitachi, Ltd.Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
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Patent number: 6881316Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes. According to the present invention, a connection plate 23 and hollow electrodes 20 are connected without solder but via a spring force. Alternatively, the hollow electrodes 20 can be connected to the connection plate 23 by utilizing volume elasticity of the connection plate.Type: GrantFiled: July 9, 2002Date of Patent: April 19, 2005Assignee: Hitachi, Ltd.Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
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Patent number: 6878256Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes. According to the present invention, a connection plate 23 and hollow electrodes 20 are connected without solder but via a spring force. Alternatively, the hollow electrodes 20 can be connected to the connection plate 23 by utilizing volume elasticity of the connection plate.Type: GrantFiled: March 19, 2002Date of Patent: April 12, 2005Assignee: Hitachi, Ltd.Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
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Publication number: 20040003994Abstract: The capillary electrophoresis device using one pressure-resistant syringe (125) is capable of automatically suctioning in polymer solution and injecting polymer solution into a capillary array (100). An electric hook (131) is installed for pulling up the syringe plunger on a push-in action type syringe (125). A check valve (124) is inserted between a polymer bottle (123) and syringe to prevent solution from flowing back into the polymer bottle. As a result, one syringe portion of polymer solution can be suctioned and injected, a large volume of polymer solution can be continuously used and device processing capability is improved.Type: ApplicationFiled: September 20, 2002Publication date: January 8, 2004Inventors: Tomihiro Shoji, Masaya Kojima, Yoshiyuki Okishima, Ryijo Inaba
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Patent number: 6660148Abstract: An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is inserted between the both syringes, and the check valve 16 works so as to prevent the gel 10 from flowing back to the charging syringe 15. As the result, the gel charging can be automated, and accordingly the processing ability of the electrophoretic instrument can be improved.Type: GrantFiled: February 26, 2001Date of Patent: December 9, 2003Assignee: Hitachi, Ltd.Inventors: Tomohiro Shoji, Yoshiyuki Okishima, Masaya Kojima, Muneo Maeshima
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Publication number: 20020179446Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes.Type: ApplicationFiled: July 9, 2002Publication date: December 5, 2002Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
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Publication number: 20020139672Abstract: The present invention easies a connection between electrodes of a capillary array device and a connection plate for supplying a high voltage to the electrodes.Type: ApplicationFiled: March 19, 2002Publication date: October 3, 2002Inventors: Syouzou Kasai, Yoshiyuki Okishima, Tomonari Morioka, Yasushi Shimizu, Hiroyuki Tanaka, Takayasu Furukawa, Noriyuki Shimoda, Seiichi Ugai
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Publication number: 20020003091Abstract: At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays having different length. Thereby, a selected capillary array constituted by collecting a plurality of capillaries can be easily attached to the electrophoresis apparatus depending on measurement purpose.Type: ApplicationFiled: May 10, 2001Publication date: January 10, 2002Inventors: Masaya Kojima, Muneo Maeshima, Yoshiyuki Okishima, Tomohiro Shoji, Wataru Matsuo
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Publication number: 20010040095Abstract: A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis, thereby, when assembling the capillary array into an electrophoresis apparatus, the same can be immediately used. Accordingly, a capillary array is provided which can be easily incorporated into an electrophoresis apparatus.Type: ApplicationFiled: May 1, 2001Publication date: November 15, 2001Inventors: Yasushi Shimizu, Toshiaki Kita, Kiyoshi Tsukada, Akihiro Suzuki, Tomonari Morioka, Masaya Kojima, Ryoji Inaba, Daizo Tokinaga, Shuhei Yamamoto, Yoshiyuki Okishima, Masao Fukunaga, Takayasu Furukawa, Tomohiro Shoji
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Publication number: 20010017263Abstract: An injection syringe 14 for injecting a gel into a capillary 111, a charging syringe 15 for charging the injection syringe 14 with the gel 10 are attached to a block 17. A check valve 16 is inserted between the both syringes, and the check valve 16 works so as to prevent the gel 10 from flowing back to the charging syringe 15. As the result, the gel charging can be automated, and accordingly the processing ability of the electrophoretic instrument can be improved.Type: ApplicationFiled: February 26, 2001Publication date: August 30, 2001Inventors: Tomohiro Shoji, Yoshiyuki Okishima, Masaya Kojima, Muneo Maeshima