Patents by Inventor Yosi Tuval

Yosi Tuval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210077676
    Abstract: Apparatus and methods are described including a left ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating. A frame is disposed around the impeller. A tube is configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube extends to a distal end of the frame and defines one or more lateral blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. Other applications are also described.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 18, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210069394
    Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A mesh is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 11, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210069395
    Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.
    Type: Application
    Filed: November 19, 2020
    Publication date: March 11, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210052794
    Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 25, 2021
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20210038794
    Abstract: Apparatus and methods are described including a ventricular assist device that includes a tube. A proximal portion of the tube traverses a subject's aortic valve, and a distal portion of the tube is disposed within the subject's left ventricle. A blood pump is disposed within the distal portion of the tube and pumps blood through the tube from the subject's left ventricle to the subject's aorta, by pumping the blood into the tube via one or more blood inlet openings that are defined by the tube and that are configured to be disposed within the subject's left ventricle, and by pumping blood out of the tube via one or more blood outlet openings that are defined by the tube and that are configured to be disposed within the subject's aorta. The one or more blood outlet openings have teardrop shapes. Other applications are also described.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 11, 2021
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20210038791
    Abstract: Apparatus and methods are described including a blood pump that is placed inside a body of subject. The blood pump includes an impeller that includes proximal and distal bushings, and that defines an axial lumen that extends from the proximal bushing to the distal bushing, a frame disposed around the impeller, and an axial shaft that passes through the proximal and distal bushings of the impeller. A distal end of a delivery catheter, and the frame and the impeller, are configured to be moved with respect to one another, to thereby cause the frame to assume a radially-constrained configuration by the frame becoming axially elongated, and cause the impeller to assume a radially-constrained configuration by the impeller becoming axially elongated. Other applications are also described.
    Type: Application
    Filed: October 13, 2020
    Publication date: February 11, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210038790
    Abstract: Apparatus comprising and methods are described including a blood pump that includes an axial shaft, and an impeller disposed on the axial shaft. The impeller is configured to pump blood of the subject by rotating. The impeller and the axial shaft are configured to undergo axial back-and-forth motion during operation of the impeller. A distal tip element is disposed at a distal end of the blood pump. The distal tip element defines an axial-shaft-receiving tube, configured to receive at least a portion of the axial shaft during forward motion of the axial shaft. The distal tip element additionally defines an atraumatic distal tip portion disposed distally of the axial-shaft-receiving tube. Other applications are also described.
    Type: Application
    Filed: October 13, 2020
    Publication date: February 11, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210038792
    Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.
    Type: Application
    Filed: October 22, 2020
    Publication date: February 11, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 10905808
    Abstract: Apparatus and methods are described including placing a blood pump into a subject's body, the blood pump including an axial shaft, an impeller disposed on the axial shaft, and a drive cable extending from outside the subject's body to the axial shaft. The impeller is driven to pump blood from a distal end of the impeller to a proximal end of the impeller by imparting rotational motion to the impeller via the drive cable, in a given direction of rotation. At least a portion of the drive cable includes a plurality of wires disposed in a coiled configuration that is such that, in response to the drive cable rotating in the given direction of rotation, the plurality of wires disposed in the coiled configuration at least partially unwind, such that the portion of the drive cable shortens axially. Other applications are also described.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: February 2, 2021
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210023287
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller, and a motor configured to drive the impeller to pump blood by rotating the impeller. The impeller is configured to undergo axial motion, in response to changes in a pressure against which the impeller is pumping. A sensor detects the axial motion of the impeller, and generates a sensor signal in response thereto. A computer processor receives the sensor signal and generates an output in response thereto. Other applications are also described.
    Type: Application
    Filed: October 14, 2020
    Publication date: January 28, 2021
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210023286
    Abstract: Apparatus and methods are described including a blood pump catheter that includes an axial shaft, and an impeller disposed on the axial shaft. A motor drives the impeller to pump blood, by rotating the impeller. A drive cable extends from the motor to the axial shaft, the drive cable being configured to impart rotational motion from the motor to the impeller by rotating. A distal tip portion is disposed at a distal end of the blood pump catheter. The drive cable, the axial shaft, and the distal tip portion define a continuous lumen therethrough from outside the subject's body to the distal end of the blood pump catheter. The continuous lumen facilitates insertion of the blood pump catheter into the subject's body over a guidewire, and, subsequently, provides a channel through which the purging fluid flows. Other applications are also described.
    Type: Application
    Filed: October 13, 2020
    Publication date: January 28, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20210023288
    Abstract: Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.
    Type: Application
    Filed: October 14, 2020
    Publication date: January 28, 2021
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 10881770
    Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller that includes proximal and distal bushings, and a frame disposed around the impeller, the frame including proximal and distal bearings. An axial shaft passes through the proximal and distal bearings of the frame and the proximal and distal bushings of the impeller. The impeller defines a radially-constrained configuration in which the impeller is introduced into the subject's body and a non-radially-constrained configuration in which the impeller is configured to pump blood within the subject's body. The impeller changes from its radially-constrained configuration to its non-radially constrained configuration by the distal bushing sliding over the axial shaft. Other applications are also described.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: January 5, 2021
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 10864310
    Abstract: Apparatus and methods are described including an impeller that includes an impeller frame that comprises proximal and distal end portions and at least one helical elongate element that winds from the proximal end portion to the distal end portion. A material is coupled to the at least one helical elongate element, such that the at least one helical elongate element with the material coupled thereto defines a blade of the impeller. A plurality of sutures are tied around the at least one helical elongate element, the sutures being configured to facilitate coupling of the material to the at least one helical elongate element. Other applications are also described.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: December 15, 2020
    Assignee: MAGENTA MEDICAL LTD.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Publication number: 20200254161
    Abstract: Apparatus and methods are described, including a blood pump that includes a catheter, a proximal impeller disposed on the catheter inside a proximal impeller housing, and which is configured to pump blood by rotating inside the proximal impeller housing. A distal impeller is disposed on the catheter inside a distal impeller housing, distally to the proximal impeller, and the distal impeller is configured to pump blood by rotating inside the distal impeller housing. A tubular element is disposed between the proximal impeller housing and the distal impeller housing, the tubular element being configured to have a tubular configuration during rotation of the proximal and distal impellers. Other applications are also described.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman, Tom Shtendel, Gad Lubinsky
  • Publication number: 20200254162
    Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A control unit drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the control unit to rotate under respective rotation conditions that are different from each other. Other applications are also described.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Publication number: 20200237984
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. The frame defines struts having a structure that is such that, as the frame transitions from a proximal end of the frame toward a center of the frame, the struts pass through junctions, at which the two struts branch from a single strut, in a Y-shape. The structure of the struts of the frame is configured such that, in response to a distal end of a delivery catheter and the frame being moved into overlapping positions with respect to each other, the frame assumes a radially-constrained configuration by becoming axially elongated, and the frame causes the impeller to assume a radially-constrained configuration by becoming axially elongated. Other applications are also described.
    Type: Application
    Filed: March 5, 2020
    Publication date: July 30, 2020
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20200237985
    Abstract: Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.
    Type: Application
    Filed: March 5, 2020
    Publication date: July 30, 2020
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20200237982
    Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube within the subject's left ventricle. A frame disposed within the distal portion of the tube defines cells, and a width of each of the cells within a cylindrical portion of the frame is less than 2 mm. An inner lining lines at least some of the cylindrical portion of the frame. An impeller is disposed inside the frame such that a gap between an outer edge of the impeller and the inner lining is less than 1 mm. The impeller is stabilized with respect to the frame, such that, during rotation of the impeller, the gap between the outer edge of the impeller and the inner lining is maintained and is substantially constant. Other applications are also described.
    Type: Application
    Filed: March 5, 2020
    Publication date: July 30, 2020
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20200237983
    Abstract: Apparatus and methods are described including manufacturing an impeller by forming a structure having first and second bushings at proximal and distal ends that are connected to one another by at least one elongate element. The elongate element is made to radially expand and form a helical elongate element. An elastomeric material is coupled to the helical elongate element, such that the helical elongate element with the elastomeric material coupled thereto defines a blade of the impeller. The coupling is performed such that a layer of the material disposed around a radially outer edge of the helical elongate element forms the effective edge of the impeller blade. A step is performed to enhance bonding of the elastomeric material to the helical elongate element in a manner that does not cause a protrusion from the effective edge of the impeller blade. Other applications are also described.
    Type: Application
    Filed: March 5, 2020
    Publication date: July 30, 2020
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld