Patents by Inventor Yosi Tuval

Yosi Tuval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240189571
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to be delivered through vasculature of a subject while the impeller is in a radially-constrained configuration. The impeller is configured to self-expand to a non-radially-constrained configuration, and to pump blood while in the non-radially-constrained configuration. A ratio between (a) a diameter of the impeller when the impeller is in its non-radially-constrained configuration at a location at which the diameter of the impeller is at its maximum and (b) a diameter of the impeller when the impeller is in its radially-constrained configuration is greater than 7:2. Other applications are also described.
    Type: Application
    Filed: February 19, 2024
    Publication date: June 13, 2024
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20240157116
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller having proximal and distal end portions, a frame disposed around the impeller, and a shaft member that passes through the proximal and distal end portions of the impeller and that is configured to impart rotational motion to the impeller. The impeller defines a radially-constrained configuration in which the impeller is introduced into a subject's body and a non-radially-constrained configuration in which the impeller is configured to pump blood within the subject's body. The distal end portion of the impeller is configured to slide over the shaft member as the impeller changes from its radially-constrained configuration to its non-radially-constrained configuration. Other applications are also described.
    Type: Application
    Filed: January 25, 2024
    Publication date: May 16, 2024
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman, Tom Shtendel, Gad Lubinsky
  • Patent number: 11964143
    Abstract: Apparatus and methods are described, including a left-ventricular assist device that includes an impeller, and a frame disposed around the impeller, the frame having a length of more than 25 mm when disposed in a non-radially constrained configuration. A rigid axial shaft extends from a proximal end of the frame to a distal end of the frame. A motor is disposed outside a body of a subject, and drives the impeller to pump blood within the subject's body, by rotating. A drive cable extends from outside the subject's body to the axial shaft. The drive cable imparts rotational motion from the motor to the impeller by rotating. The drive cable is a flexible cable comprising a plurality of coiled wires. Other applications are also described.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: April 23, 2024
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Patent number: 11950889
    Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: April 9, 2024
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 11944800
    Abstract: Apparatus and methods are described including a blood pump configured to be placed inside a body of subject, the blood pump including an impeller configured to pump the subject's blood by rotating, and an axial shaft upon which the impeller is disposed. Proximal and distal radial bearings are configured to stabilize the axial shaft radially during rotation of the impeller. An atraumatic distal-tip portion is disposed distally with respect to the impeller, the atraumatic distal-tip portion including an inflatable portion. A purging fluid is pumped toward the distal-tip portion, such as to (a) purge the distal bearing, and (b) inflate the inflatable portion of the distal-tip portion. Other applications are also described.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: April 2, 2024
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Patent number: 11944413
    Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A mesh is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: April 2, 2024
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20240090780
    Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject, and a frame configured to be disposed around the impeller. The frame is shaped such that, in a non-radially constrained configuration of the frame, the frame defines a cylindrical central portion, and a distal conical portion that is disposed distally with respect to the cylindrical central portion and that widens from a distal end of the frame to a distal end of the cylindrical central portion. The frame defines struts that define openings therebetween, and all openings that are defined at least partially within the distal conical portion of the frame extend into the cylindrical central portion of the frame. Other applications are also described.
    Type: Application
    Filed: November 16, 2023
    Publication date: March 21, 2024
    Inventors: Yosi Tuval, Zev SOHN, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 11883274
    Abstract: Apparatus and methods are described for improving renal function of a patient, including mechanically occluding the patient's inferior vena cava downstream of the renal vein ostium to form an upstream region and a downstream region of the inferior vena cava, and mechanically pumping blood through the inferior vena cava from the upstream region to a discharge location in the downstream region while the inferior vena cava is occluded, wherein the blood remains in the inferior vena cava while being mechanically pumped. Other applications are also described.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: January 30, 2024
    Assignee: Magenta Medical Ltd.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 11850415
    Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A motor drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the motor to rotate under respective rotation conditions that are different from each other. Other applications are also described.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: December 26, 2023
    Assignee: Magenta Medical Ltd.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 11844592
    Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle. A frame is disposed around the impeller, the frame defining generally-cylindrical central portion, and a proximal conical portion that widens from a proximal end of the frame to a proximal end of the generally-cylindrical central portion. A motor drives the impeller to pump blood from the left ventricle to the subject's aorta, by rotation of the impeller. The impeller is configured to be disposed at least partially within the proximal conical portion of the frame during at least some of a time during which the impeller rotates. Other applications are also described.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: December 19, 2023
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 11839754
    Abstract: Apparatus and methods are described including a tube configured to traverse a subject's aortic valve. A frame is disposed within a portion of the tube, and a plurality of winged projections are coupled to the frame. An impeller is disposed inside the tube, the impeller including proximal and distal bushings, a helical elongate element, and a spring disposed inside of the helical elongate element, the spring defining a lumen therethrough. A film of material is supported between the helical elongate element and the spring. A rigid shaft extends from the proximal bushing to the distal bushing via the lumen defined by the spring. The impeller is rotated, such as to pump blood from the subject's left ventricle to the subject's aorta. Other applications are also described.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: December 12, 2023
    Assignee: Magenta Medical Ltd
    Inventors: Yosi Tuval, Daniel Glozman, Gad Lubinsky
  • Patent number: 11839540
    Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition that causes the subject to have elevated central venous pressure. In response thereto, a device is placed inside the subject's vena cava, and the device is deployed inside the subject's vena cava, such that, in a passive manner, the device reduces blood pressure within the subject's renal veins relative to the subject's central venous pressure. Other applications are also described.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: December 12, 2023
    Assignee: Magenta Medical Ltd
    Inventor: Yosi Tuval
  • Patent number: 11806116
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller, and a motor configured to drive the impeller to pump blood by rotating the impeller. The impeller is configured to undergo axial motion, in response to changes in a pressure against which the impeller is pumping. A sensor detects the axial motion of the impeller, and generates a sensor signal in response thereto. A computer processor receives the sensor signal and generates an output in response thereto. Other applications are also described.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: November 7, 2023
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Patent number: 11806117
    Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft, an impeller disposed on the axial shaft, a frame disposed around the impeller, and a motor disposed outside a subject's body, and configured to drive the impeller to pump blood from a distal end of the impeller to a proximal end of the impeller. A drive cable extends from outside the subject's body to the axial shaft, and is configured to impart rotational motion from the motor to the impeller by rotating. The drive cable is held in a preloaded state with respect to the frame, such that initiation of pumping of blood by rotation of the impeller does not cause the drive cable to axially elongate. Other applications are also described.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: November 7, 2023
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky
  • Publication number: 20230233837
    Abstract: Apparatus and methods are described including a blood pump that includes at least one motor configured to be disposed outside a body of a subject, a catheter, a proximal impeller disposed on the catheter and configured to pump blood by rotating, and a distal impeller disposed on the catheter. The distal impeller is configured to pump blood by rotating and is disposed on the catheter distally to the proximal impeller such that longitudinal centers of the proximal and distal impellers are separated from each other by at least 3 cm. Other applications are also described.
    Type: Application
    Filed: April 3, 2023
    Publication date: July 27, 2023
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman, Tom Shtendel, Gad Lubinsky
  • Publication number: 20230233841
    Abstract: Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A first impeller cage is disposed around the first impeller, and a second impeller cage is disposed around the second impeller. A sleeve extends longitudinally along more than 50 percent of a distance between the first and second impellers. Other applications are also described.
    Type: Application
    Filed: April 4, 2023
    Publication date: July 27, 2023
    Inventors: Yosi Tuval, Ehud Schwammenthal, Daniel Glozman, Gad Lubinksy
  • Publication number: 20230233836
    Abstract: Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A frame is treated in order to enhance bonding between an inner surface of the frame and an inner lining. Subsequently, the inner lining is coupled to the inner surface of the frame along at least a portion of a central cylindrical portion of the frame. Subsequent to coupling the inner lining to the inner surface of the frame along at least a portion of the central cylindrical portion of the frame, a portion of an elongate tube is placed around at least a portion of the frame. While heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.
    Type: Application
    Filed: March 16, 2023
    Publication date: July 27, 2023
    Inventors: Yosi Tuval, Gad Lubinsky, Hagit Zemer Harel, Ori Friedland, Daniel Rosenblum, Avi Rozenfeld
  • Publication number: 20230233840
    Abstract: Apparatus and methods are described including a blood pump that includes a catheter, a first impeller disposed on the catheter, and a second impeller disposed on the catheter, proximally to the first impeller. A motor drives the first and second impellers to pump blood of a subject, by driving the first and second impellers to rotate. The blood pumps is configured such that (a) the first and second impellers are shaped differently from each other when the first and second impellers are in non-radially-constrained configurations, (b) the first and second impellers are sized differently from each other when the first and second impellers are in non-radially-constrained configurations, and/or (c) the first and second impellers are driven by the motor to rotate under respective rotation conditions that are different from each other. Other applications are also described.
    Type: Application
    Filed: April 4, 2023
    Publication date: July 27, 2023
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Publication number: 20230226342
    Abstract: Apparatus and methods are described including a left-ventricular assist device that includes an impeller (50) and a frame (34) disposed around the impeller (50). The frame (34) includes strut junctions (33) at a proximal end of the frame, the strut junctions (33) being configured to be maintained in open states, during assembly of the left ventricular assist device, to facilitate insertion of the impeller (50) into the frame (34). A securing element (117) holds the struts junctions in closed states, subsequent to the insertion of the impeller (50) into the frame (34). A pump-outlet tube (24) extends to a distal end of the frame (34) and defines one or more lateral blood inlet openings (108) that are configured to allow blood to flow from the subject's left ventricle into the pump-outlet tube (24). Other applications are also described.
    Type: Application
    Filed: March 7, 2022
    Publication date: July 20, 2023
    Inventors: Yosi Tuval, Gad Lubinsky, Hagit Zemer Harel, Ori Friedland, Daniel Rosenblum, Avi Rozenfeld
  • Publication number: 20230218884
    Abstract: Apparatus and methods are described including a left-ventricular assist device including an impeller and a frame disposed around the impeller. A pump-outlet tube traverses the subject's aortic valve with a distal portion of the pump-outlet tube disposed within the subject's left ventricle. The distal portion of the pump-outlet tube extends to a distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame. The porosity of the distal portion of the pump-outlet tube is lower within a proximal region of the distal portion of the pump-outlet tube than within a distal region of the distal portion of the pump-outlet tube that is distal to the proximal region. Other applications are also described.
    Type: Application
    Filed: March 15, 2023
    Publication date: July 13, 2023
    Inventors: Yosi Tuval, Gad Lubinsky, Hagit Zemer Harel, Ori Friedland, Daniel Rosenblum, Avi Rozenfeld