Patents by Inventor Yosi Tuval

Yosi Tuval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220355096
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. During operation of the blood pump, the impeller moves with respect to the frame, and a range of movement of the impeller is such that at least a first portion of the impeller is disposed within the proximal conical portion of the frame during at least some of the operation of the blood pump, and at least a second portion of the impeller is disposed within the cylindrical portion of the frame during at least some of the operation of the blood pump. Other applications are also described.
    Type: Application
    Filed: July 5, 2022
    Publication date: November 10, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Patent number: 11484701
    Abstract: Apparatus and methods are described including a catheter, a first pump disposed on the catheter, and a second pump disposed on the catheter, proximally to the first pump. A control unit is configured to control activation of the first and second pumps. The first and second pumps are configured, when activated, to pump fluid in opposite directions from one another. Other applications are also described.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: November 1, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 11484699
    Abstract: Apparatus and methods are described including coupling a rigid tube to a drive cable that comprises a plurality of coiled wires, by placing ends of the drive cable and the rigid tube at a given location within a butt-welding overtube. The ends of the drive cable and the rigid tube are visible when they are disposed at the given location within the butt-welding overtube, via a window defined by the butt-welding overtube. The placement of the drive cable within the butt-welding overtube is such that a helical groove within a portion of the butt-welding overtube is disposed over the drive cable. Welding rings are formed around the butt-welding overtube. Other applications are also described.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: November 1, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Patent number: 11471663
    Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. The frame defines struts having a structure that is such that, as the frame transitions from a proximal end of the frame toward a center of the frame, the struts pass through junctions, at which the two struts branch from a single strut, in a Y-shape. The structure of the struts of the frame is configured such that, in response to a distal end of a delivery catheter and the frame being moved into overlapping positions with respect to each other, the frame assumes a radially-constrained configuration by becoming axially elongated, and the frame causes the impeller to assume a radially-constrained configuration by becoming axially elongated. Other applications are also described.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: October 18, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220241574
    Abstract: Apparatus and methods are described including delivering a left-ventricular assist device to a subject's aorta. The device including a distal-tip element that defines a straight proximal portion, and a curved distal portion, the curved distal portion defining first and second curves with an elongated straight portion between the first and second curves. The distal-tip element is centered with respect to the aortic valve using the curved distal portion of the distal-tip element, to thereby guide the device through the subject's aortic valve atraumatically. A pump pumps blood through from the subject's left ventricle to the subject's aorta. Other applications are also described.
    Type: Application
    Filed: April 18, 2022
    Publication date: August 4, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Jacob Leisner Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220241576
    Abstract: Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta. A curved element is disposed within the tube and is configured to cause at least a portion of the tube to become curved. Other applications are also described.
    Type: Application
    Filed: April 19, 2022
    Publication date: August 4, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Jacob Leisner Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220241575
    Abstract: Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta such as to cause the proximal portion of the tube to be maintained in an open state, and to cause at least a portion of the tube to become curved. Other applications are also described.
    Type: Application
    Filed: April 18, 2022
    Publication date: August 4, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Jacob Leisner Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220226632
    Abstract: Apparatus and methods are described including an impeller (50) that includes a proximal bushing (64) and a distal bushing (58). Two or more helical elongate elements (52) extend from the proximal bushing (64) to the distal bushing (58), and an axial structure (54) is disposed inside of the two or more helical elongate elements (52), and along an axis around which the helical elongate elements (52) wind. The impeller (50) includes an impeller-overexpansion-prevention element (72). The impeller-overexpansion-prevention element is a single integrated structure that includes a ring (73) disposed around the axial structure (54), and a plurality of elongate elements (67) each of the elongate elements (67) extending from the ring to a respective helical elongate element (52) and being coupled to the respective helical elongate element (52) so as to prevent radial expansion of the impeller (50). Other applications are also described.
    Type: Application
    Filed: April 6, 2021
    Publication date: July 21, 2022
    Inventors: Yosi Tuval, Yinnon Elisha, David Israeli, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yuval Zipory, Avi Rozenfeld, Aurelie Benaddi, Gilad Moiseyev, Yuri Sudin
  • Publication number: 20220218976
    Abstract: Apparatus and methods are described for use with a venous system of a subject that includes one or more tributary vessels that flow into a vein at junctions. A blood-pump-catheter (70) includes a material (36) configured to be placed at a downstream location that is downstream of the junctions and to at least partially occlude blood flow through the vein. The material defines a blood-outlet opening (31). A blood pump (24) pumps blood from a region of the vein that is adjacent to the junctions, and through the blood-outlet opening (31). A blood-flow pathway (60) directs upstream venous blood flow from an upstream location that is upstream of the junctions, to downstream of the material (36), without the upstream venous blood flow being pumped by the pump (24). Other applications are also described.
    Type: Application
    Filed: May 20, 2020
    Publication date: July 14, 2022
    Inventors: Ori Friedland, Yuval Zipory, Yuri Sudin, Ayelet Haimy, Ehud Schwammenthal, Yosi Tuval, Tak Gee Cheung
  • Publication number: 20220184372
    Abstract: Apparatus and methods are described including a ventricular assist device that includes a frame having struts that define a plurality of cells. In its non-radially-constrained configuration, the frame includes a generally cylindrical portion. A tube defines blood outlet openings, and a portion of the tube is disposed outside the frame and is coupled to the generally cylindrical portion of the frame, such that the portion of the tube conforms with a structure of struts of the frame. An inner lining is coupled to an inside of the generally cylindrical portion of the frame, such as to provide the generally cylindrical portion of the frame with a smooth inner surface. An impeller is disposed at least partially inside the generally cylindrical portion of the frame and is configured to pump blood through the tube and out of the one of more blood outlet openings. Other applications are also described.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 16, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220184371
    Abstract: Apparatus and methods are described including a ventricular assist device configured to assist ventricular functioning of a subject. The ventricular assist device includes an impeller and a frame disposed around the impeller. An axial shaft extends from a proximal end of the frame to a distal end of the frame, the impeller being coupled to the axial shaft. The axial shaft includes a proximal portion and a distal portion, which are coupled to each other via a joint. The proximal portion and the distal portion of the axial shaft are configured to flex with respect to each other via the joint. Other applications are also described.
    Type: Application
    Filed: February 23, 2022
    Publication date: June 16, 2022
    Inventors: Yosi Tuval, Yinnon Elisha, David Israeli, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yuval Zipory, Avi Rozenfeld, Aurelie Benaddi, Gilad Moiseyev, Yuri Sudin
  • Publication number: 20220184375
    Abstract: Apparatus and methods are described including a ventricular assist device that includes a blood pump configured to be placed inside a left ventricle of a subject and to pump blood from the subject's left ventricle to an aorta of the subject. A blood pressure sensor measures aortic pressure of the subject. A computer processor varies a flow rate that is that is generated by the blood pump, and determines a relationship between arterial pulsatility of the subject and the flow rate that is generated by the blood pump, based upon aortic pressure that is measured by the blood pressure sensor as the flow rate that is generated by the blood pump is varied. The computer processor estimates native cardiac output of the subject at least partially based upon the relationship. Other applications are also described.
    Type: Application
    Filed: February 28, 2022
    Publication date: June 16, 2022
    Inventors: Yosi Tuval, Yinnon Elisha, David Israeli, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yuval Zipory, Avi Rozenfeld, Aurelie Benaddi, Gilad Moiseyev, Yuri Sudin
  • Publication number: 20220184376
    Abstract: Apparatus and methods are described including a left-ventricular assist device that includes an impeller configured to be placed inside a subject's left ventricle and to pump blood from the left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the aorta and a distal portion of the tube is disposed within the left ventricle. The distal portion of the tube extends to the distal end of the frame and defines more than 10 blood-inlet openings that are sized such as (a) to allow blood to flow from the subject's left ventricle into the tube and (b) to block structures from the subject's left ventricle from entering into the frame. Other applications are also described.
    Type: Application
    Filed: February 28, 2022
    Publication date: June 16, 2022
    Inventors: Yosi Tuval, Yinnon Elisha, David Israeli, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yuval Zipory, Avi Rozenfeld, Aurelie Benaddi, Gilad Moiseyev, Yuri Sudin
  • Publication number: 20220176098
    Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube within the subject's left ventricle. A frame disposed within the distal portion of the tube defines cells, and a width of each of the cells within a generally cylindrical portion of the frame is less than 2 mm. An inner lining lines at least some of the cylindrical portion of the frame. An impeller is disposed inside the frame. Other applications are also described.
    Type: Application
    Filed: February 22, 2022
    Publication date: June 9, 2022
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Publication number: 20220151774
    Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition that causes the subject to have elevated central venous pressure. In response thereto, a device is placed inside the subject's vena cava, and the device is deployed inside the subject's vena cava, such that, in a passive manner, the device reduces blood pressure within the subject's renal veins relative to the subject's central venous pressure. Other applications are also described.
    Type: Application
    Filed: September 28, 2021
    Publication date: May 19, 2022
    Inventor: Yosi Tuval
  • Publication number: 20220134083
    Abstract: Apparatus and methods are described including a tube configured to traverse an aortic valve of a subject. A frame is disposed within at least a portion of the tube. An impeller rotates such as to pump blood from the subject's left ventricle to the subject's aorta. The impeller is disposed inside the tube such that, when the impeller and the tube are deployed inside the subject, and prior to rotation of the impeller, a gap between an outer edge of the impeller and an inner surface of the tube is less than 1 mm. A rigid stabilizing element stabilizes the impeller with respect to the tube, such that during rotation of the impeller, a gap between the outer edge of the impeller and the inner surface of the tube is maintained. Other applications are also described.
    Type: Application
    Filed: January 13, 2022
    Publication date: May 5, 2022
    Inventors: Yosi Tuval, Daniel Glozman, Gad Lubinsky
  • Publication number: 20220117732
    Abstract: Apparatus and methods are provided including a mitral valve prosthesis. The prosthesis includes an inner support structure having downstream and upstream sections, the upstream section having a cross-sectional area greater than the downstream section. The inner support structure is configured to be positioned on an atrial side of the native valve complex, and to prevent the prosthesis from being dislodged into the left ventricle. A prosthetic valve having prosthetic valve leaflets is coupled to the inner support structure. An outer support structure has engagement arms, downstream ends of the engagement arms being coupled to the inner support structure. The prosthesis is configured such that, upon implantation thereof: downstream ends of the native valve leaflets, downstream ends of the engagement arms, and downstream ends of the prosthetic leaflets, are disposed at a longitudinal distance from one another of less than 3 mm. Other embodiments are also described.
    Type: Application
    Filed: December 27, 2021
    Publication date: April 21, 2022
    Inventors: Yosi Tuval, Ilia Hariton, Igor Kovalsky, Eli Ben-Hamou
  • Patent number: 11298523
    Abstract: Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: April 12, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Yosi Tuval, Zev Sohn, Ehud Schwammenthal, Gad Lubinsky, Victor Troshin, Shaul Mustacchi, Yinnon Elisha, Yuri Sudin, Hagit Zemer Harel, Avi Rozenfeld
  • Patent number: 11298521
    Abstract: Apparatus and methods are described including manufacturing an impeller by coupling a material to a helical elongate element, such that the helical elongate element with the material coupled thereto defines a blade of the impeller. A portion of a structure that includes the helical elongate element is dipped into the material while the material is in a liquid state. The material is dried, while the material is being supported by the at least one helical elongate element. During the drying of material, the structure is rotated about its longitudinal axis, such as to facilitate the formation of a film of the material having a substantially uniform thickness within the impeller blade. Other applications are also described.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: April 12, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman
  • Patent number: 11298520
    Abstract: Apparatus and methods are described including an impeller that includes an impeller frame that comprises proximal and distal end portions and at least one helical elongate element that winds from the proximal end portion to the distal end portion. A film of material is coupled to the at least one helical elongate element, such that the helical elongate element with the film of material coupled thereto defines a blade of the impeller. The film of material is shaped to define a hollow central lumen therethrough. Other applications are also described.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: April 12, 2022
    Assignee: Magenta Medical Ltd.
    Inventors: Ehud Schwammenthal, Yosi Tuval, Daniel Glozman