Patents by Inventor Yossan-Var TAN

Yossan-Var TAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATORY
    Publication number: 20190151304
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases. The inventors showed that orexin receptor antagonists have anti-inflammatory properties. Indeed, these compounds are antagonist for OX1R-mediated calcium mobilization but a full agonist for OX1R-mediated mitochondrial apoptosis, which is the mechanism involved in the improvement of resolution of inflammation observed in the models of colitis, multiple sclerosis and pancreatitis. In particular, the present invention relates to a method of treating an autoimmune inflammatory disease in a subject in need thereof comprising administering to the subject a therapeutically effective amount of at least one OX1R antagonist.
    Type: Application
    Filed: May 9, 2017
    Publication date: May 23, 2019
    Inventors: Yossan-Var TAN, Catalina ABAD RABAT, Thierry VOISIN, Alain COUVINEAU
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AUTOIMMUNE INFLAMMATORY DISEASES
    Publication number: 20180305458
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of autoimmune inflammatory disease. In particular, the present invention relates to a method of treating an autoimmune inflammatory disease in a subject in need thereof comprising administering to the subject a therapeutically effective amount of at least one OX1R agonist.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 25, 2018
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ PARIS DIDEROT - PARIS 7, UNIVERSITÉ DE ROUEN NORMANDIE
    Inventors: Yossan-Var TAN, Catalina ABAD-RABAT, Alain COUVINEAU, Thierry VOISIN