Patents by Inventor Yossi Gottfried

Yossi Gottfried has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR DELIVERY COMPOSITIONS
    Publication number: 20240148886
    Abstract: Protein conjugates comprising a protein carrier comprising polyethylenimine, a payload that interacts with an intracellular target and a linker are provided. Pharmaceutical composition comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided.
    Type: Application
    Filed: October 18, 2023
    Publication date: May 9, 2024
    Inventors: Orit SHILOVITZKY, Lilach CHEN ZELTSBURG, Rozi Ravit UZAN GUETA, Ayala LEWKOWICZ, Yossi GOTTFRIED, Rotem FAYGENBOIM-ORNAI, Motti HAKIM, Yair SAPIR, Ilana MANDEL, Tehila BEN-MOSHE, Avidor SHULMAN
  • Induction of apoptosis via ARTS-IAP complexes
    Publication number: 20050227302
    Abstract: The present invention provides complexes containing an ARTS protein and an IAP protein, compounds that disrupt same, and use of the compounds in treating neuro-degenerative disease, ischemic injury, myelodysplasia, atherosclerosis, various auto-immune diseases, cytopenia, pancreatitis, and periodonitis, and in decreasing susceptibility of a cell to apoptosis. The present invention also provides methods for identifying biologically active regions of ARTS protein, and use of mimetic compounds of same in treating apoptosis-related disorders, cancer, and other neoplastic diseases and disorders.
    Type: Application
    Filed: January 4, 2005
    Publication date: October 13, 2005
    Inventors: Sarit Larisch, Yossi Gottfried