Patents by Inventor Yossi MANDEL

Yossi MANDEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTRACELLULAR DELIVERY COMPOSITIONS
    Publication number: 20240148886
    Abstract: Protein conjugates comprising a protein carrier comprising polyethylenimine, a payload that interacts with an intracellular target and a linker are provided. Pharmaceutical composition comprising the protein conjugates as well as methods of using and producing the protein conjugates are also provided.
    Type: Application
    Filed: October 18, 2023
    Publication date: May 9, 2024
    Inventors: Orit SHILOVITZKY, Lilach CHEN ZELTSBURG, Rozi Ravit UZAN GUETA, Ayala LEWKOWICZ, Yossi GOTTFRIED, Rotem FAYGENBOIM-ORNAI, Motti HAKIM, Yair SAPIR, Ilana MANDEL, Tehila BEN-MOSHE, Avidor SHULMAN
  • CONJUGATES COMPRISING OCULAR ANGIOGENESIS GROWTH FACTOR APTAMERS AND USES THEREOF IN THE DETECTION AND TREATMENT OF OPHTHALMOLOGICAL ANGIOGENESIS INDICATIONS
    Publication number: 20200000934
    Abstract: Provided is an antiangiogenic agent in the form of a vehicle, e.g., a nanoparticle associated (directly or indirectly) with at least one ocular angiogenesis growth factor aptamer, wherein said association labile to interaction between the aptamer and an ocular angiogenesis growth factor.
    Type: Application
    Filed: February 28, 2018
    Publication date: January 2, 2020
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Bar Ilan University
    Inventors: Itamar WILLNER, Sharon ETERY, Yossi MANDEL, Amos MARKUS, Asaf SHOVAL