Patents by Inventor Yossi Tuval
Yossi Tuval has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10213302Abstract: Heart valve prostheses are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame including a first portion and a second portion. In the collapsed configuration, the first portion is positioned adjacent to the second portion. In the expanded configuration, the first portion moves to be positioned within an interior area of the second portion.Type: GrantFiled: June 24, 2015Date of Patent: February 26, 2019Assignee: MEDTRONIC, INC.Inventors: Igor Kovalsky, Ilia Hariton, Yossi Tuval, Nadav Yellin
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Publication number: 20180214265Abstract: A prosthetic heart valve having identifiers for aiding in radiographic positioning is described.Type: ApplicationFiled: March 29, 2018Publication date: August 2, 2018Applicant: Medtronic, Inc.Inventors: Yossi Tuval, Raphael Benary
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Publication number: 20180161158Abstract: The present invention is directed to prostheses including a support structure having a proximal end and a distal end, and a motion limiting member attached to the distal end of the support structure, wherein the motion limiting member is configured to restrict radial expansion of the distal end of the support structure. Methods for delivering the prosthesis are also provided.Type: ApplicationFiled: February 12, 2018Publication date: June 14, 2018Inventors: Igor Kovalsky, Yossi Tuval
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Publication number: 20180147053Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.Type: ApplicationFiled: January 29, 2018Publication date: May 31, 2018Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
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Publication number: 20180110620Abstract: In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.Type: ApplicationFiled: December 5, 2017Publication date: April 26, 2018Inventors: Igor Kovalsky, Jason Quill, Daniel Glozman, Ilia Hariton, Yossi Tuval, Nadav Yellin
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Patent number: 9943407Abstract: Methods for implanting a collapsible prosthetic heart valve having commissural posts including the steps of placement through a blood vessel, using a fluoroscopic image, and rotationally aligning at least one post with a native commissure.Type: GrantFiled: March 9, 2015Date of Patent: April 17, 2018Assignee: Medtronic, Inc.Inventors: Yossi Tuval, Raphael Bernary
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Patent number: 9918833Abstract: The present invention is directed to prostheses including a support structure having a proximal end and a distal end, and a motion limiting member attached to the distal end of the support structure, wherein the motion limiting member is configured to restrict radial expansion of the distal end of the support structure. Methods for delivering the prosthesis are also provided.Type: GrantFiled: August 24, 2011Date of Patent: March 20, 2018Assignee: Medtronic Vascular GalwayInventors: Igor Kovalsky, Yossi Tuval
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Patent number: 9913714Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.Type: GrantFiled: June 10, 2016Date of Patent: March 13, 2018Assignee: MEDTRONIC, INC.Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
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Patent number: 9867698Abstract: In some embodiments, a valve prosthesis includes an inlet portion that is substantially s-shaped and configured to engage the floor of the outflow tract of the native heart atrium. In some embodiments, a valve prosthesis includes a chordae guiding element configured to reduce bending of the chordae to reduce stress on the chordae during the cardiac cycle. In some embodiments, a valve prosthesis includes a central portion having an hourglass shape configured to pinch a native annulus in order to provide axial fixation of the valve prosthesis within a valve site. In some embodiments, a valve prosthesis includes a frame having an outflow end that is flared to provide a gap between an outflow end of the frame and an outflow end of prosthetic leaflets when the prosthetic leaflets are fully opened.Type: GrantFiled: December 8, 2015Date of Patent: January 16, 2018Assignee: Medtronic, Inc.Inventors: Igor Kovalsky, Jason Quill, Daniel Glozman, Illia Hariton, Yossi Tuval, Nadav Yellin
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Publication number: 20170128207Abstract: A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described.Type: ApplicationFiled: January 26, 2017Publication date: May 11, 2017Inventors: Yossi Tuval, Igor Kovalsky, Ido Kilemnik, Eli Benhamou
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Patent number: 9592120Abstract: A prosthesis for implantation at a native semilunar valve includes a prosthetic distal valve, which includes a pliant material configured to collapse inwardly towards a longitudinal axis of the prosthesis during diastole, and to open outwardly during systole, and a distal fixation member configured to be positioned in a downstream artery of the subject. The apparatus also includes a proximal fixation member coupled to the distal fixation member, and configured to be positioned at least partially on a ventricular side of the native semilunar valve. The proximal fixation member is shaped so as to define a lattice that is shaped so as to define an intermediary portion that is coupled to the pliant material of the valve and diverges outwardly from the longitudinal axis, and a distal portion that is distal to the intermediary portion and diverges outwardly from the intermediary portion of the lattice. Other embodiments are also described.Type: GrantFiled: August 12, 2014Date of Patent: March 14, 2017Assignee: Medtronic Ventor Technologies, Ltd.Inventors: Yossi Tuval, Igor Kovalsky, Ido Kilemnik, Eli Benhamou
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Publication number: 20170065263Abstract: Aspects of the present invention provide apparatuses and methods for closing an apical hole in a heart of a subject, including a hole-closure device that includes a tissue-attachment portion configured to attach to cardiac tissue around the apical hole, and a collapsible portion coupled to the tissue-attachment portion and configured to close the hole by collapsing inwardly inside the apical hole.Type: ApplicationFiled: November 17, 2016Publication date: March 9, 2017Inventor: Yossi Tuval
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Publication number: 20170056167Abstract: A mitral valve prosthesis and methods for implanting the prosthesis transapically (i.e., through the apex of the heart), transatrially (i.e., through the left atrium of the heart), and transseptally (i.e., through the septum of the heart). The prosthesis generally includes a self-expanding frame and two or more support arms. A valve prosthesis is sutured to the self-expanding frame. Each support arm corresponds to a native mitral valve leaflet. At least one support arm immobilizes the native leaflets, and holds the native leaflets close to the main frame.Type: ApplicationFiled: November 10, 2016Publication date: March 2, 2017Inventor: Yossi Tuval
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Patent number: 9579197Abstract: A valve retainer is connected to an elongate delivery member. The valve retainer is configured to releasably secure a prosthesis (e.g., a heart valve prosthesis) to the delivery member during delivery to a target site in a body (e.g., a native valve annulus). The valve retainer includes a rotational identifier that identifies the rotational orientation of the valve retainer when the valve retainer is positioned proximate to the target site. A heart valve prosthesis can include a commissural post that has a predetermined rotational position relative to the rotational identifier, such that the heart valve prosthesis can be rotationally aligned with the native commissures of the native valve by rotating the delivery member and the valve retainer until the commissural post is aligned with a native valve commissure and the rotational identifier is visible.Type: GrantFiled: December 14, 2011Date of Patent: February 28, 2017Assignee: Medtronic Vascular, Inc.Inventors: Niall Duffy, Gerry McCaffrey, Noam Miller, Yossi Tuval, Daniel Glozman
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Patent number: 9526483Abstract: Aspects of the present invention provide apparatuses and methods for closing an apical hole in a heart of a subject, including a hole-closure device that includes a tissue-attachment portion configured to attach to cardiac tissue around the apical hole, and a collapsible portion coupled to the tissue-attachment portion and configured to close the hole by collapsing inwardly inside the apical hole.Type: GrantFiled: July 11, 2011Date of Patent: December 27, 2016Assignee: Medtronic Vascular GalwayInventor: Yossi Tuval
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Publication number: 20160354203Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.Type: ApplicationFiled: June 10, 2016Publication date: December 8, 2016Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik
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Publication number: 20160331524Abstract: Apparatus and methods are provided for use with a mitral valve of a heart of a subject. The apparatus includes a P1-anchor, a P2-anchor, and a P3-anchor, that are anchored to tissue in a vicinity of, respectively, P1, P2 and P3 segments of a posterior leaflet of the mitral valve, a tether being fixedly coupled to the P2-anchor, and slidably coupled to the P1 and P3 anchors. A cardiac-site anchor anchors the tether to an anchoring location that is at a cardiac site that is anterior and inferior to the posterior leaflet. Other embodiments are also described.Type: ApplicationFiled: July 28, 2016Publication date: November 17, 2016Inventors: Yossi Tuval, Ilia Hariton
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Publication number: 20160310271Abstract: Apparatus and methods are provided, including a plurality of anchoring elements, each of the anchoring elements being an elongate element that is curved to define an opening. A housing holds each of the anchoring elements. A mandrel is reversibly disposable through the openings defined by the anchoring elements. The anchoring elements are configured such that, in response to removal of the mandrel from the openings, ends of the anchoring elements automatically move outwardly, and diameters of the openings decrease, due to elastic loading of the anchoring elements. Other embodiments are also described.Type: ApplicationFiled: April 26, 2016Publication date: October 27, 2016Inventor: Yossi Tuval
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Patent number: 9414823Abstract: Medical devices for closing a hole or holes in a subject's body, such as those related to transapical procedures, are disclosed. The medical devices can include a force-providing portion and a tissue-attachment portion. The medical devices can be configured for multiple positions including at least a constrained position and an unconstrained position. In some embodiments, the medical device may be used on a delivery device or delivery tool. In some embodiments, the force-providing portion can pivot radially outward and the tissue-attachment portion can become more constrained, and the hole can be at least partially closed. In some embodiments, the tissue-attachment portion can include a plurality of pins that assume a hook shape.Type: GrantFiled: March 7, 2013Date of Patent: August 16, 2016Assignee: Medtronic Ventor Technologies Ltd.Inventors: Eli Ben Hamou, Yossi Tuval
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Patent number: 9387071Abstract: A prosthesis is provided for implantation at a native semilunar valve of a native valve complex, the native valve complex having three semilunar sinuses and three native commissures. The prosthesis includes a valve prosthesis support, which comprises a support structure comprising exactly three engagement arms that meet one another at three respective junctures. The engagement arms are shaped so as define three peak complexes at the three respective junctures, and three trough complexes, each of which is between two of the peak complexes. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses, such that each of the peak complexes is disposed distal to and in rotational alignment with a respective one of the native commissures, and each of the trough complexes is disposed at least partially within the respective one of the semilunar sinuses.Type: GrantFiled: September 12, 2014Date of Patent: July 12, 2016Assignee: Medtronic, Inc.Inventors: Yossi Tuval, Raphael Benary, Ido Kilemnik