Abstract: A biometric information authenticating device includes a biometric information sensor to detect contact of an operating finger with a reading surface and to read biometric information of the operating finger, an illumination unit including at least one light source, and a control unit to indicate completion of reading of the biometric information by an illumination pattern including a combination of turning on and off of the at least one light source.

Abstract: A machine tool (1) includes a spindle (32) supported on a support surface (37a) of a support body (37) with such an orientation that the longitudinal axis of the spindle extends along the support surface (37a). The spindle (32) is movable in a vertical direction that is perpendicular to the longitudinal axis of the spindle (32). The support body (37) is provided with a ventilation hole (80) extending through the support body (37) between the support surface (37a) and a surface (37b) facing in the direction opposite to the support surface (37a), to open toward the spindle (32).

Abstract: Provided are a coolant supply device and a machine tool in which ejection of a coolant is easily switched on and off. A coolant supply device 10 for supplying a coolant to a workpiece machining area in a machine tool, the coolant supply device comprising: a rotary nozzle 40 formed to have a cylindrical shape and having, at an outer circumferential face thereof having the cylindrical shape, an ejection port 51 for ejecting the coolant; and a supply device body 20 rotatably supporting the rotary nozzle and configured to be capable of supplying the coolant to the rotary nozzle. The supply device body is configured to be capable of switching an ejection allowed range in which the ejection port is opened and an ejection stopped range in which the ejection port is blocked from each other in accordance with rotation of the rotary nozzle.

Abstract: It is intended to provide a novel compound or a salt thereof, or crystals of the compound or the salt, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl. [Solution] The present invention provides a pyridone derivative having a tetrahydropyranylmethyl group represented by the following formula (I) having various substituents, or a salt thereof, or crystals of the compound or the salt (wherein R1, R2, R3, R4, R5, W, X, Y, and Z are each as defined in the specification).

Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.

Abstract: A machine tool (1) includes a spindle (32) supported on a support surface (37a) of a support body (37) with such an orientation that the longitudinal axis of the spindle extends along the support surface (37a). The spindle (32) is movable in a vertical direction that is perpendicular to the longitudinal axis of the spindle (32). The support body (37) is provided with a ventilation hole (80) extending through the support body (37) between the support surface (37a) and a surface (37b) facing in the direction opposite to the support surface (37a), to open toward the spindle (32).

Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.

Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.

Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.

Abstract: The present disclosure provides novel compounds or salts thereof, or crystals of the compounds or the salts, which inhibit Axl and are useful in the treatment of a disease caused by hyperfunction of Axl, the treatment of a disease associated with hyperfunction of Axl, and/or the treatment of a disease involving hyperfunction of Axl.

Abstract: A method for machining a work in a work machining apparatus provided with a movable main spindle moving between a work supply position and a work take-out position, includes arranging a tool rest on the movable main spindle to move integrally with the movable main spindle, supplying the work at the work supply position to the movable main spindle, moving the movable main spindle from the work supply position toward the work take-out position, machining the work held on the movable spindle with a tool of the tool rest while moving the movable main spindle from the work supply position toward the work take-out position, and taking out the work at the work take-out position from the movable main spindle.

Abstract: A work machining apparatus capable of reducing the stand-by time in each main spindle as much as possible and can improve the operation ratio is provided. In a work machining apparatus having at least one movable spindle 22 which moves forward and backward between the work supply position and the work take-out position, in which a work is supplied to movable main spindle 22 at the supply position, the movable main spindle 22 is moved from the supply position to the take-out position and the work is taken out from the movable main spindle 22 at the supply position, whereby the work is conveyed from the supply position to the take-out position, wherein a tool rest 6 corresponding to the movable main spindle 22 is provided integrally with the movable main spindle 22 and movably on the movable spindle 22, thereby enabling the tool on the tool rest 6 to process the work held on the movable main spindle 22 during the conveyance movement of the work by the movable main spindle 22.

Abstract: An automatic lathe is capable of rapidly and easily switching between machining of a material with a guide bush and machining of the material without the guide bush. The automatic lathe has a guide bush support table, a support table fixing device for fixing the guide bush support table, a guide member rotatably installed on the guide bush support table so as not to move forward and backward, a guide bush detachably fitted to the tip of the guide member, a driving device for rotating the guide bush, a rotation transmission device for transmitting the rotation of the guide member to the spindle, and a spindle moving device for moving the spindle forward and backward within the guide member. A spindle fixing device positions and fixes the spindle at a specified position on the guide bush support table when the guide bush is removed from the guide member.

Abstract: An automatic lathe is provided which is capable of rapidly and easily switching between machining of a material with a guide bush and machining of the material without the guide bush. The automatic lathe has a head stock (6) and a guide bush support table (1). The head stock (6) is provided with a spindle drive motor (8). The guide bush support table (1) is provided with a guide bush rotating motor (11). There are provided: support table fixing means (15) for positioning and fixing the guide bush support table (1); a guide member (12) rotatably installed on the guide bush support table (1) and regulated so as not to move forward and backward and having a through-hole formed for a spindle (3) to be inserted therein; a guide bush (4) detachably fitted to the tip of the guide member (12); and spindle fixing means (37) for positioning and fixing the spindle (3) on the guide bush support table (1) at a specified position when the guide bush (4) is removed from the guide member (12).

Abstract: An automatic lathe is provided which is capable of rapidly and easily switching between machining of a material with a guide bush and machining of the material without the guide bush.

Abstract: An automatic lathe is provided which is capable of rapidly and easily switching between machining of a material with a guide bush and machining of the material without the guide bush. The automatic lathe has a head stock (6) and a guide bush support table (1). The head stock (6) is provided with a spindle drive motor (8). The guide bush support table (1) is provided with a guide bush rotating motor (11). There are provided: support table fixing means (15) for positioning and fixing the guide bush support table (1); a guide member (12) rotatably installed on the guide bush support table (1) and regulated so as not to move forward and backward and having a through-hole formed for a spindle (3) to be inserted therein; a guide bush (4) detachably fitted to the tip of the guide member (12); and spindle fixing means (37) for positioning and fixing the spindle (3) on the guide bush support table (1) at a specified position when the guide bush (4) is removed from the guide member (12).

Abstract: A material guide device (10) comprises a guide bush (22) having a material support part (20) elastically displaceable in a radial direction, and an adjusting mechanism (24) adjusting the radial dimension of the material support part of the guide bush. The adjusting mechanism further comprises a carrying member (40) having a front face (40b) disposed around the material lead-out end (22b) of the guide bush and carrying the guide bush, a pressing member (42) disposed near the front face of the carrying member movably relative to the carrying member and linearly movably relative to the guide bush along a guiding axis and causing the radial elastic displacement on the material support part by the relative linear motion, and a feed screw structure (44) causing the relative linear motion between the pressing member and the guide bush by the screwing motion of a screw.

Abstract: A method for testing a therapeutic or preventive agent for hyperlipidemia, and a nucleic acid probe, a primer, and an antibody which are used in the method. Specifically, a method for testing the effect of a test substance as a therapeutic or preventive agent for hyperlipidemia by expression of a gene having a sequence as set forth in SEQ ID No. 1 or SEQ ID No. 2 of the Sequence Listing which participates in regulation of neutral-fat concentration in the blood of a mammal, and a nucleic acid probe, primer or antibody used for the method. The present invention makes it possible to search for a candidate substance for a therapeutic or preventive agent for hyperlipidemia.

Abstract: A method for testing a therapeutic or preventive agent for hyperlipidemia, and a nucleic acid probe, a primer, and an antibody which are used in the method. Specifically, a method for testing the effect of a test substance as a therapeutic or preventive agent for hyperlipidemia by expression of a gene having a sequence as set forth in SEQ ID No. 1 or SEQ ID No. 2 of the Sequence Listing which participates in regulation of neutral-fat concentration in the blood of a mammal, and a nucleic acid probe, primer or antibody used for the method. The present invention makes it possible to search for a candidate substance for a therapeutic or preventive agent for hyperlipidemia.

Abstract: A method for testing a therapeutic or preventive agent for hyperlipidemia, and a nucleic acid probe, a primer, and an antibody which are used in the method. Specifically, a method for testing the effect of a test substance as a therapeutic or preventive agent for hyperlipidemia by expression of a gene having a sequence as set forth in SEQ ID No. 1 or SEQ ID No. 2 of the Sequence Listing which participates in regulation of neutral-fat concentration in the blood of a mammal, and a nucleic acid probe, primer or antibody used for the method. The present invention makes it possible to search for a candidate substance for a therapeutic or preventive agent for hyperlipidemia.