Abstract: An ultrasound endoscope includes an insertion tube configured to be inserted into a subject, the insertion tube including a transducer that includes a plurality of piezoelectric devices that are aligned along a circumferential direction about a center axis of the insertion tube, an observation optical portion configured to capture a subject image, a first built-in material that is different from the observation optical portion, and a support configured to support the observation optical portion and the first built-in material, the transducer including a through hole configured to pierce through along the center axis to insert the support, and the support including a first groove that extends along the center axis, the first groove being configured to support the observation optical portion, and a second groove that extends along the center axis, the second groove being configured to support the first built-in material and communicate with the first groove.

Abstract: A distal end body of an endoscope includes: an outer portion defining an internal space and including a partition, the partition having a first through hole, the partition partitioning the internal space into a first space and a second space; a first sealing portion including a second through hole, the first sealing portion being fitted in the first through hole in a state of protruding from the first through hole toward the first space; and an inner portion being fitted in the second through hole.

Abstract: An endoscope comprising: an insertion portion; a raising base provided at a distal end of the insertion portion; a wire configured to move in a raising direction to raise the raising base; a biasing element attached to the wire and configured to apply to the wire a biasing force in the raising direction; and an operation portion coupled to a proximal end of the insertion portion, the operation portion including a switching mechanism having a first state and a second state. The switching mechanism is configured to switch between the first state and the second state. In the first state, the switching mechanism prevents the biasing force from moving the wire in the raising direction and, in the second state, the switching mechanism allows the biasing force to move the wire in the raising direction.

Abstract: An ultrasound endoscope includes an insertion tube configured to be inserted into a subject, the insertion tube including a transducer that includes a plurality of piezoelectric devices that are aligned along a circumferential direction about a center axis of the insertion tube, an observation optical portion configured to capture a subject image, a first built-in material that is different from the observation optical portion, and a support configured to support the observation optical portion and the first built-in material, the transducer including a through hole configured to pierce through along the center axis to insert the support, and the support including a first groove that extends along the center axis, the first groove being configured to support the observation optical portion, and a second groove that extends along the center axis, the second groove being configured to support the first built-in material and communicate with the first groove.

Abstract: An endoscope includes: a bendable tube that is bendable in at least one direction; a flexible tube coupled to a proximal end side of the bendable tube; an operating wire inserted inside the bendable tube and the flexible tube, the operating wire being configured to move axially to bend the bendable tube in the at least one direction; an operating unit coupled to a proximal end side of the flexible tube, the operating unit being configured to receive a first user operation of moving the operating wire axially to bend the bendable tube in the at least one direction; a brake mechanism provided at a proximal end portion of the bendable tube, the brake mechanism being configured to regulate the movement of the operating wire in response to given power; and an actuating member configured to receive a second user operation of actuating the brake mechanism.

Abstract: An endoscope includes: a bending portion that is provided at a distal end of an insertion section, has plural bending pieces consecutively provided, and is bendable in at least one direction; a flexible tube provided at a proximal end side of the bending portion with flexibility; a control body that is provided at a proximal end side of the flexible tube and receives operation causing the bending portion to be bent; a wire that is inserted through the bending portion and the flexible tube and transmits the operation received by the control body to the distal end of the insertion section; a protruding portion being a plate-like member provided on the wire; and a holding portion that is provided on an inner peripheral surface of the bending piece and holds the protruding portion movably in a direction that the insertion section extends.

Abstract: The purpose is to provide a compound which can overcomes the disadvantages of conventional steroid drugs and NSAID. It is found that specific epoxy monohydroxy forms of eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid which are independently represented by formulae [chemical formula 1], [chemical formula 5] and the like have an inhibitory activity on neutrophils. This compound can inhibit the invasion of neutrophils into tissues and the activation of neutrophils which are observed in acute inflammations.

Abstract: The purpose is to provide a compound which can overcomes the disadvantages of conventional steroid drugs and NSAID. It is found that specific epoxy monohydroxy forms of eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid which are independently represented by formulae [chemical formula 1], [chemical formula 5] and the like have an inhibitory activity on neutrophils. This compound can inhibit the invasion of neutrophils into tissues and the activation of neutrophils which are observed in acute inflammations.

Abstract: It is intended to provide a method for producing aglycone from a glycoside efficiently at low cost without using an acid catalyst or an organic solvent. The method for producing aglycone, characterized by bringing a glycoside into contact with high temperature high pressure water. The temperature of the high temperature high pressure water is generally from 100 to 374° C., preferably from 140 to 320° C., more preferably from 200 to 300° C. The pressure of the high temperature high pressure water may be not lower than the saturated water vapor pressure at the temperature, i.e., a pressure at which the liquid state is maintained.

Abstract: It is intended to provide a method for producing aglycone from a glycoside efficiently at low cost without using an acid catalyst or an organic solvent. The method for producing aglycone, characterized by bringing a glycoside into contact with high temperature high pressure water. The temperature of the high temperature high pressure water is generally from 100 to 374° C., preferably from 140 to 320° C., more preferably from 200 to 300° C. The pressure of the high temperature high pressure water may be not lower than the saturated water vapor pressure at the temperature, i.e., a pressure at which the liquid state is maintained.

Abstract: It is intended to provide a method of easily and economically producing starch which has an increased content of less digestible starch. The method of producing starch having a high content of less digestible starch is characterized by comprising contacting starch with hot water at a temperature of 160 to 260° C. which has a pressure corresponding to the saturated vapor pressure at that temperature or more.

Abstract: To promote the growth of human beings or animals, prevent the onset of diarrhea and prevent or ameliorate various diseases, it is intended to provide a substance which has an effect of decreasing eosinophils in the intestinal tract and a feed comprising the same as a feed additive. Namely, an intestinal eosinophil-suppressing composition which contains an ?-linked galactooligosaccharide as the active ingredient. When added in an amount of from 0.01 to 10% by weight, in terms of the saccharide, to an animal feed, this composition is useful in providing an intestinal eosinophil-suppressing feed.