Patents by Inventor Yosuke Kamimura

Yosuke Kamimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PROMOTING DIVERSIFICATION OF ANTIBODY VARIABLE REGION
    Publication number: 20230220049
    Abstract: A method for promoting diversification of variable regions of an antibody, particularly a method for promoting diversification of the amino acid sequences of variable regions of an antibody generated by an avian B cell population, the method including suppressing the PI3K? activity of each avian B cell comprised in the avian B cell population expressing the antibody.
    Type: Application
    Filed: January 3, 2023
    Publication date: July 13, 2023
    Inventors: Keisuke Niikura, Yosuke Kamimura
  • Method for promoting diversification of antibody variable region
    Patent number: 11572402
    Abstract: The present invention relates to a method for promoting diversification of variable regions of an antibody. Specifically, the present invention relates to a method for promoting diversification of the amino acid sequences of variable regions of an antibody generated by an avian B cell population, wherein the method comprises suppressing the PI3K? activity of each avian B cell comprised in the avian B cell population expressing the antibody.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: February 7, 2023
    Assignee: CHIOME BIOSCIENCE INC.
    Inventors: Keisuke Niikura, Yosuke Kamimura
  • Method for obtaining antibody
    Patent number: 11008566
    Abstract: The present invention relates to a method for obtaining an antibody from an avian B cell antibody library, comprising the following steps (a) to (d): (a) a step of allowing an avian B cell antibody library to come into contact with an antigen in the presence of a calcineurin inhibitor and avian serum, (b) a step of selecting avian B cells that bind to the antigen in the step (a), (c) a step of culturing the avian B cells selected in the step (b) in the presence of a calcineurin inhibitor and avian serum, and (d) a step of obtaining the avian B cells obtained through the step (c) and/or an antibody expressed by the avian B cells.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 18, 2021
    Assignee: Chiome Bioscience Inc.
    Inventors: Yosuke Kamimura, Kotaro Yamamoto
  • METHOD FOR PROMOTING DIVERSIFICATION OF ANTIBODY VARIABLE REGION
    Publication number: 20190359691
    Abstract: The present invention relates to a method for promoting diversification of variable regions of an antibody. Specifically, the present invention relates to a method for promoting diversification of the amino acid sequences of variable regions of an antibody generated by an avian B cell population, wherein the method comprises suppressing the PI3K? activity of each avian B cell comprised in the avian B cell population expressing the antibody.
    Type: Application
    Filed: February 9, 2018
    Publication date: November 28, 2019
    Inventors: Keisuke Niikura, Yosuke Kamimura
  • METHOD FOR OBTAINING ANTIBODY
    Publication number: 20190233811
    Abstract: The present invention relates to a method for obtaining an antibody from an avian B cell antibody library, comprising the following steps (a) to (d): (a) a step of allowing an avian B cell antibody library to come into contact with an antigen in the presence of a calcineurin inhibitor and avian serum, (b) a step of selecting avian B cells that bind to the antigen in the step (a), (c) a step of culturing the avian B cells selected in the step (b) in the presence of a calcineurin inhibitor and avian serum, and (d) a step of obtaining the avian B cells obtained through the step (c) and/or an antibody expressed by the avian B cells.
    Type: Application
    Filed: September 29, 2017
    Publication date: August 1, 2019
    Inventors: Yosuke Kamimura, Kotaro Yamamoto