Patents by Inventor Yosuke MORIYAMA
Yosuke MORIYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10851342Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore, upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.Type: GrantFiled: December 14, 2017Date of Patent: December 1, 2020Assignee: Saitama Medical UniversityInventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
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Patent number: 9972431Abstract: A laminated coil component has an element body formed by laminating a plurality of ceramic layers, and a coil conductor disposed inside the element body. The coil conductor has coil pattern portions disposed on the plurality of the ceramic layers and including line portions and land portions disposed at ends of the line portions, and pattern connecting portions connecting the land portion to each other between the coil pattern portions arranged adjacently in a laminating direction of the ceramic layers. The land portions overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction such that the centers of the land portions do not overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction.Type: GrantFiled: March 24, 2016Date of Patent: May 15, 2018Assignee: Murata Manufacturing Co., Ltd.Inventors: Yosuke Moriyama, Mitsuru Odahara, Akihiro Ono
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Publication number: 20180094239Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore, upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.Type: ApplicationFiled: December 14, 2017Publication date: April 5, 2018Inventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
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Patent number: 9868934Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.Type: GrantFiled: October 29, 2013Date of Patent: January 16, 2018Assignee: Saitama Medical UniversityInventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
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Publication number: 20160284463Abstract: A laminated coil component has an element body formed by laminating a plurality of ceramic layers, and a coil conductor disposed inside the element body. The coil conductor has coil pattern portions disposed on the plurality of the ceramic layers and including line portions and land portions disposed at ends of the line portions, and pattern connecting portions connecting the land portion to each other between the coil pattern portions arranged adjacently in a laminating direction of the ceramic layers. The land portions overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction such that the centers of the land portions do not overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction.Type: ApplicationFiled: March 24, 2016Publication date: September 29, 2016Applicant: Murata Manufacturing Co., Ltd.Inventors: Yosuke MORIYAMA, Mitsuru ODAHARA, Akihiro ONO
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Publication number: 20150275171Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.Type: ApplicationFiled: October 29, 2013Publication date: October 1, 2015Applicant: Saitama Medical UniversityInventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
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Patent number: 9123465Abstract: A laminated body is formed by stacking insulating layers to be formed into a rectangular parallelepiped shape. A linear conductor is stacked together with the insulating layers and connects end surfaces of the laminated body that are opposed to each other with respect to a first direction. Lengths of the end surfaces of the laminated body in a second direction, which is perpendicular to the stacking direction and the first direction, are equal to or smaller than the lengths of the end surfaces in the stacking direction.Type: GrantFiled: November 19, 2013Date of Patent: September 1, 2015Assignee: Murata Manufacturing Co., Ltd.Inventor: Yosuke Moriyama
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Publication number: 20140070912Abstract: A laminated body is formed by stacking insulating layers to be formed into a rectangular parallelepiped shape. A linear conductor is stacked together with the insulating layers and connects end surfaces of the laminated body that are opposed to each other with respect to a first direction. Lengths of the end surfaces of the laminated body in a second direction, which is perpendicular to the stacking direction and the first direction, are equal to or smaller than the lengths of the end surfaces in the stacking direction.Type: ApplicationFiled: November 19, 2013Publication date: March 13, 2014Applicant: MURATA MANUFACTURING CO., LTD.Inventor: Yosuke MORIYAMA