Patents by Inventor Yosuke MORIYAMA

Yosuke MORIYAMA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10851342
    Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore, upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: December 1, 2020
    Assignee: Saitama Medical University
    Inventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
  • Patent number: 9972431
    Abstract: A laminated coil component has an element body formed by laminating a plurality of ceramic layers, and a coil conductor disposed inside the element body. The coil conductor has coil pattern portions disposed on the plurality of the ceramic layers and including line portions and land portions disposed at ends of the line portions, and pattern connecting portions connecting the land portion to each other between the coil pattern portions arranged adjacently in a laminating direction of the ceramic layers. The land portions overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction such that the centers of the land portions do not overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: May 15, 2018
    Assignee: Murata Manufacturing Co., Ltd.
    Inventors: Yosuke Moriyama, Mitsuru Odahara, Akihiro Ono
  • Publication number: 20180094239
    Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore, upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.
    Type: Application
    Filed: December 14, 2017
    Publication date: April 5, 2018
    Inventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
  • Patent number: 9868934
    Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: January 16, 2018
    Assignee: Saitama Medical University
    Inventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
  • Publication number: 20160284463
    Abstract: A laminated coil component has an element body formed by laminating a plurality of ceramic layers, and a coil conductor disposed inside the element body. The coil conductor has coil pattern portions disposed on the plurality of the ceramic layers and including line portions and land portions disposed at ends of the line portions, and pattern connecting portions connecting the land portion to each other between the coil pattern portions arranged adjacently in a laminating direction of the ceramic layers. The land portions overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction such that the centers of the land portions do not overlap with the line portions located on the opposite side of the pattern connecting portions in the laminating direction when viewed in the laminating direction.
    Type: Application
    Filed: March 24, 2016
    Publication date: September 29, 2016
    Applicant: Murata Manufacturing Co., Ltd.
    Inventors: Yosuke MORIYAMA, Mitsuru ODAHARA, Akihiro ONO
  • Publication number: 20150275171
    Abstract: The present invention allows a TET1 protein to be more stably expressed in human pluripotent stem cells than in the past by, inter alia, substituting the second amino acid from the amino terminal of a TET1 protein with a different amino acid. Furthermore upon differentiation of said pluripotent stem cells, it is possible to quickly eliminate the expression of, inter alia, NANOG, which is an inhibitor of differentiation and promote the expression of factors related to differentiation by introducing a variant TET1 protein to a pluripotent stem cell. The present invention provides a method for manufacturing pluripotent stem cells with increased differentiation potential, and a substance that is useful to said method.
    Type: Application
    Filed: October 29, 2013
    Publication date: October 1, 2015
    Applicant: Saitama Medical University
    Inventors: Hidemasa Kato, Yosuke Moriyama, Keiko Hiraki, Akihiko Okuda
  • Patent number: 9123465
    Abstract: A laminated body is formed by stacking insulating layers to be formed into a rectangular parallelepiped shape. A linear conductor is stacked together with the insulating layers and connects end surfaces of the laminated body that are opposed to each other with respect to a first direction. Lengths of the end surfaces of the laminated body in a second direction, which is perpendicular to the stacking direction and the first direction, are equal to or smaller than the lengths of the end surfaces in the stacking direction.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: September 1, 2015
    Assignee: Murata Manufacturing Co., Ltd.
    Inventor: Yosuke Moriyama
  • Publication number: 20140070912
    Abstract: A laminated body is formed by stacking insulating layers to be formed into a rectangular parallelepiped shape. A linear conductor is stacked together with the insulating layers and connects end surfaces of the laminated body that are opposed to each other with respect to a first direction. Lengths of the end surfaces of the laminated body in a second direction, which is perpendicular to the stacking direction and the first direction, are equal to or smaller than the lengths of the end surfaces in the stacking direction.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 13, 2014
    Applicant: MURATA MANUFACTURING CO., LTD.
    Inventor: Yosuke MORIYAMA