Patents by Inventor Yosuke Ueki

Yosuke Ueki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220405717
    Abstract: A maintenance plan assistance system 100 configured to include: holding, in a storage device 101, remaining life information relating to devices covered by a maintenance plan, and a list of maintenance menus; and a computation device 104 identifying a maintenance effect when each maintenance menu is applied to each of the devices based on the maintenance menus and temporal changes in failure probabilities of each of the devices indicated by the remaining life information, identifying a variable range of a condition-based maintenance implementation timing, the variable range being dependent on the maintenance effect, and determining a maintenance menu including the variable range for a predetermined maintenance timing, and outputting, to a predetermined device, information including the maintenance menu identified by the determination and the condition-based maintenance implementation timing changed to the predetermined maintenance timing.
    Type: Application
    Filed: October 15, 2020
    Publication date: December 22, 2022
    Applicant: HITACHI, LTD.
    Inventors: Takahide SHINGE, Kaoru AMIMOTO, Ippei NUMATA, Yosuke UEKI
  • Publication number: 20220357734
    Abstract: The problem of the present invention is to establish how to more accurately estimate the failure probabilities of the components of a machine system that has a small number of failure records.
    Type: Application
    Filed: June 10, 2020
    Publication date: November 10, 2022
    Applicant: Hitachi, Ltd.
    Inventors: Hiroaki AMAKAWA, Yosuke UEKI, Takahide SHINGE
  • Publication number: 20220300470
    Abstract: The problem of the present invention is how to identify a failure probability function that defines failure occurrences of a device or a component of the device that is operated while undergoing maintenance in consideration of effects of the maintenance.
    Type: Application
    Filed: November 19, 2020
    Publication date: September 22, 2022
    Applicant: Hitachi, Ltd.
    Inventors: Yosuke UEKI, Takahide SHINGE
  • Publication number: 20220270235
    Abstract: Provided are a fracture surface analysis apparatus and a fracture surface analysis method which enable a non-expert to conduct a fracture surface analysis just as well as an expert does. This fracture surface analysis apparatus is characterized by including a microscopic region observation unit that is provided with a first means for calculating an accuracy of fracture mode by using a first observation image, of a microscopic region of a to-be-analyzed object, acquired by an imaging means, a second means for calculating an observation condition for improving the accuracy of the fracture mode, and a third means for adjusting conditions for imaging the microscopic region by the imaging means, and that outputs the accuracy of fracture mode and the observation condition for improving the accuracy of fracture mode to a visualization means.
    Type: Application
    Filed: April 7, 2020
    Publication date: August 25, 2022
    Applicant: Hitachi, Ltd.
    Inventors: Yohei ISOSAKI, Yosuke UEKI
  • Patent number: 11090386
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: August 17, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Publication number: 20210089928
    Abstract: The remaining life of a component of a mechanical system is predicted with high accuracy. A failure probability evaluation system evaluates a failure of a component of each mechanical system for a mechanical system group including a plurality of mechanical systems, and includes a failure history database for accumulating past failure history data about the mechanical system. A time-series operation database stores time-series physical quantity data representing an operating state of the mechanical system. A failure rate function identification unit calculates a failure rate function of a mechanical system by statistical processing based on the failure history data, and a damage model generation/update unit having a function of generating an explanatory variable expression of a failure rate function which minimizes a variation in life is defined by the failure rate function using the time-series physical quantity data.
    Type: Application
    Filed: January 24, 2019
    Publication date: March 25, 2021
    Inventor: Yosuke UEKI
  • Patent number: 10620621
    Abstract: To provide high-accuracy assessment of a remaining life of a composite material structure. A remaining life assessment system 5 for composite material structure includes: a load history assessment part 7 that calculates a history of load on a composite material based on output from a first sensor attached to the composite material; a state quantity assessment part 10 that calculates a state quantity of the composite material based on output from the first sensor or a second sensor; a state quantity change database 13 that holds previously recorded relation between the load history and the state quantity of the composite material; and a comparative assessment part 12 that compares the calculated load history and state quantity with the load history and state quantity stored in the state quantity change database 13.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: April 14, 2020
    Assignee: Hitachi, Ltd.
    Inventor: Yosuke Ueki
  • Publication number: 20190018403
    Abstract: To provide high-accuracy assessment of a remaining life of a composite material structure. A remaining life assessment system 5 for composite material structure includes: a load history assessment part 7 that calculates a history of load on a composite material based on output from a first sensor attached to the composite material; a state quantity assessment part 10 that calculates a state quantity of the composite material based on output from the first sensor or a second sensor; a state quantity change database 13 that holds previously recorded relation between the load history and the state quantity of the composite material; and a comparative assessment part 12 that compares the calculated load history and state quantity with the load history and state quantity stored in the state quantity change database 13.
    Type: Application
    Filed: January 19, 2017
    Publication date: January 17, 2019
    Inventor: Yosuke UEKI
  • Publication number: 20180318422
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: July 18, 2018
    Publication date: November 8, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Patent number: 10117876
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d] [1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: November 6, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • Publication number: 20180263998
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Application
    Filed: October 8, 2015
    Publication date: September 20, 2018
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • Patent number: 10076524
    Abstract: The present invention provides a pharmaceutical composition comprising a compound represented by formula (1): or N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d] [1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide, or a pharmaceutically acceptable salt of the foregoing, and a salt of a compound having a C12-22 saturated aliphatic hydrocarbon group.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: September 18, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro Zaima, Kazuo Kazama, Shuntaro Arase, Kentaro Nagane, Kanta Horie, Yosuke Ueki
  • Patent number: 9981040
    Abstract: An object of the present invention is to provide a capsule formulation comprising a phosphonooxymethyl derivative of ravuconazole which suppresses delay in dissolution due to storage regardless of an encapsulated amount of the phosphonooxymethyl derivative of ravuconazole. The present invention provides a capsule formulation comprising an encapsulated material comprising {[(1R,2R)-2-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-1-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-ylmethyl)propyl]oxy}methyl dihydrogen phosphate or a pharmacologically acceptable salt thereof, or a solvate of any of the foregoing, and a capsule shell not comprising gelatin.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: May 29, 2018
    Assignee: Eisai R&D Management Co., Ltd.
    Inventor: Yosuke Ueki
  • Publication number: 20180028662
    Abstract: The present invention provides a method for suppressing bitterness of a quinoline derivative.
    Type: Application
    Filed: February 23, 2016
    Publication date: February 1, 2018
    Inventors: Kentaro Nagane, Yosuke Ueki, Shusuke Sano, Takahisa Sakaguchi
  • Publication number: 20150118299
    Abstract: An object of the present invention is to provide a capsule formulation comprising a phosphonooxymethyl derivative of ravuconazole which suppresses delay in dissolution due to storage regardless of an encapsulated amount of the phosphonooxymethyl derivative of ravuconazole. The present invention provides a capsule formulation comprising an encapsulated material comprising {[(1R,2R)-2-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-1-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-ylmethyl)propyl]oxy}methyl dihydrogen phosphate or a pharmacologically acceptable salt thereof, or a solvate of any of the foregoing, and a capsule shell not comprising gelatin.
    Type: Application
    Filed: April 17, 2013
    Publication date: April 30, 2015
    Inventor: Yosuke Ueki
  • Publication number: 20140099366
    Abstract: An object of the present invention is to provide, for the case of implementing a therapeutic method in which at least two kinds of anti-dementia drugs are used together, a composition that has a good therapeutic effect on dementia, and also gives excellent compliance. Another object of the present invention is to provide a composition containing at least two kinds of anti-dementia drugs, in which release of the anti-dementia drugs from the composition is controlled, whereby a combined effect of the anti-dementia drugs can be achieved well. Still another object of the present invention is to provide a composition for which the frequency of administration and the amount taken are reduced and hence compliance can be improved, and a method of manufacturing such a composition.
    Type: Application
    Filed: December 13, 2013
    Publication date: April 10, 2014
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Susumu Kimura, Yosuke Ueki, Masami Nohara, Yukifumi Dota
  • Patent number: 8507527
    Abstract: The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: August 13, 2013
    Assignee: EISAI R & D Management Co., Ltd.
    Inventors: Yosuke Ueki, Yasuyuki Suzuki, Satoshi Fujioka
  • Patent number: 8481565
    Abstract: The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug.
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: July 9, 2013
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yosuke Ueki, Yasuyuki Suzuki, Satoshi Fujioka
  • Publication number: 20110045074
    Abstract: A matrix type sustained-release preparation and a manufacturing method therefor are provided wherein dissolution with low pH dependence of a basic drug or a salt thereof at the early stage of dissolution can be ensured in a dissolution test, and wherein as the dissolution test proceeds, a ratio of a dissolution rate of the basic drug or the salt thereof in an acidic test solution to a dissolution rate of the basic drug or the salt thereof in a neutral test solution (dissolution rate in the acidic test solution/dissolution rate in the neutral test solution) decreases with dissolution time at the late stage of dissolution, as compared to the early stage of dissolution. According to the present invention, the matrix type sustained-release preparation contains a basic drug or a salt thereof and at least one enteric polymer, in which solubility of the basic drug or the salt thereof in a 0.1 N hydrochloric acid solution and a neutral aqueous solution, pH 6.0 is higher than in a basic aqueous solution, pH 8.0.
    Type: Application
    Filed: October 22, 2010
    Publication date: February 24, 2011
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Yosuke Ueki, Satoshi Fujioka
  • Publication number: 20100152164
    Abstract: The present invention provides a method for stabilizing an anti-dementia drug in a pharmaceutical composition containing the anti-dementia drug and a high molecular weight basic substance by adding a high molecular weight acidic substance to said pharmaceutical composition. Further, the present invention provides a pharmaceutical composition containing an anti-dementia drug and a high molecular basic substance in which a high molecular weight acidic substance is contained for stabilizing the anti-dementia drug. Furthermore, the present invention provides a method for manufacturing a pharmaceutical composition which comprises steps wherein a solution or suspension containing a high molecular weight acidic substance is added to a mixture of an anti-dementia drug and a high molecular weight basic substance for the sake of stabilizing the anti-dementia drug.
    Type: Application
    Filed: February 25, 2010
    Publication date: June 17, 2010
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Yosuke Ueki, Yasuyuki Suzuki, Satoshi Fujioka