Abstract: The present invention relates to the technical field of mass spectra. Disclosed are a novel ion storage system and method based on a quadrupole-ion trap tandem mass spectrometry. The system sequentially comprises a heating capillary, a tube lens, a skimmer, a first ion guide, a second ion guide, a quadrupole mass analyzer, an ion trap mass analyzer, and a detector; a first lens is provided between the first ion guide and the second ion guide; a second lens and a third lens are provided between the second ion guide and the quadrupole mass analyzer, wherein operation modes of the first ion guide and the second ion guide comprise an ion transmission mode and an ion storage mode. Compared with conventional time sequence control methods, more ions are stored during the same time according to the present invention, thereby improving the sensitivity of the instrument.

Abstract: The present application relates to a nano-liter photoionization mass spectrometry ion source device and an operation method thereof. The nano-liter photoionization mass spectrometry ion source device includes a nano-tip, configured to load a sample solution, thus achieving a nano-electrospray process; a metal electrode, inserted into the nano-tip to contact with the sample solution directly, thus providing a high-voltage electric field for the nano-electrospray; and a UV lamp, configured to emit a high-energy ultraviolet photon to be combined with a gaseous molecule obtained by vaporizing the sample solution, thus achieving a photoionization process. Directed to the problems such as low ionization efficiency, poor sensitivity and more impurity interference existing in the unicellular mass spectrometry process of trace low-polar compounds in small-volume samples, a nano-liter photoionization mass spectrometry ion source device suitable for the analysis on low-polar compounds in small volume, e.g.

Abstract: A composite magnetic nanomaterial based on a DNA tetrahedron, preparation therefor and use thereof are provided. The preparation method include the steps of synthesizing a DNA tetrahedron by means of a self-assembly reaction of single-stranded DNA chains, loading magnetic nanoparticles on the surfaces of molybdenum disulfide particles, modifying gold nanoparticles on exposed active sulfur atoms of the molybdenum disulfide particles, modifying the DNA tetrahedron on the gold nanoparticles, and bonding a protein antibody on the DNA tetrahedron. The composite magnetic nanomaterial is used for enriching and detecting low-abundance proteins in serum, and specific low-abundance proteins in the serum can be efficiently and selectively enriched by means of the specific reaction between an antigen and an antibody.

Abstract: An apparatus and a method for quantitative detection of gases are provided. The apparatus for quantitative detection of gases includes: a cavity ring-down spectroscopy device configured to quantitatively detect any characteristic gas in gases to be detected; a sample processing device disposed in a downstream of the cavity ring-down spectroscopy device and connected to the cavity ring-down spectroscopy device; and a mass spectrometry device disposed in a downstream of the sample processing device and configured to detect all the gases to be detected. Quantitative analysis of any variety of gases may be achieved without using standard gas in the technical solution proposed by the present application. Since no standard gas is required, the technology has significantly increased flexibility, and can be used for routine laboratory testing, for online analysis at industrial sites, as well as detection and analysis in environmental protection, national defense, aviation, aerospace, military and other fields.

Abstract: The present invention relates to the technical field of mass spectra. Disclosed are a novel ion storage system and method based on a quadrupole-ion trap tandem mass spectrometry. The system sequentially comprises a heating capillary, a tube lens, a skimmer, a first ion guide, a second ion guide, a quadrupole mass analyzer, an ion trap mass analyzer, and a detector; a first lens is provided between the first ion guide and the second ion guide; a second lens and a third lens are provided between the second ion guide and the quadrupole mass analyzer, wherein operation modes of the first ion guide and the second ion guide comprise an ion transmission mode and an ion storage mode. Compared with conventional time sequence control methods, more ions are stored during the same time according to the present invention, thereby improving the sensitivity of the instrument.

Abstract: An apparatus and a method for quantitative detection of gases are provided. The apparatus for quantitative detection of gases includes: a cavity ring-down spectroscopy device configured to quantitatively detect any characteristic gas in gases to be detected; a sample processing device disposed in a downstream of the cavity ring-down spectroscopy device and connected to the cavity ring-down spectroscopy device; and a mass spectrometry device disposed in a downstream of the sample processing device and configured to detect all the gases to be detected. Quantitative analysis of any variety of gases may be achieved without using standard gas in the technical solution proposed by the present application. Since no standard gas is required, the technology has significantly increased flexibility, and can be used for routine laboratory testing, for online analysis at industrial sites, as well as detection and analysis in environmental protection, national defense, aviation, aerospace, military and other fields.

Abstract: A stab-resistant syringe needle with an elastic protective cap and a stab-resistant syringe are provided, which include the elastic protective cap. After the syringe is used to complete injection, the protective cap can be automatically ejected through simple operations to shield a steel needle, so as to achieve a purpose of preventing stab wounds.

Abstract: A mass spectrometry device comprises a reaction gas introduction device and a gas phase molecule-ion reaction mass spectrometry analysis device, wherein the reaction gas introduction device is connected to the gas phase molecule-ion reaction mass spectrometry analysis device; the reaction gas introduction device is configured to introduce reaction gas into the gas phase molecule-ion reaction mass spectrometry analysis device; and the gas phase molecule-ion reaction mass spectrometry analysis device is configured to enable molecules or ions to be subjected to a reaction and carry out mass spectrometry analysis on a reaction result. The reaction gas introduction device comprises a reaction gas container, the reaction gas container being configured to contain gas or volatile liquid or solid and generate gas molecules needed by a reaction; and a reaction gas quantitation device, configured to carry out flow control on the gas molecules.

Abstract: The invention proposes a mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules, and a method for operating same. The mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules includes a quadrupole tandem special linear ion trap mass analyzer, a vacuum ultraviolet lamp, a lamp front shutter, a gradient vacuum system and other necessary components for the mass spectrometry apparatus. In addition, the invention also proposes a method for operating the apparatus to efficiently store ions, fragment and analyze the ions, perform ultraviolet efficient ionization on lost neutral molecules, and then analyze the ions.

Abstract: The invention proposes a mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules, and a method for operating same. The mass spectrometry apparatus for ultraviolet light ionization of neutral lost molecules includes a quadrupole tandem special linear ion trap mass analyzer, a vacuum ultraviolet lamp, a lamp front shutter, a gradient vacuum system and other necessary components for the mass spectrometry apparatus. In addition, the invention also proposes a method for operating the apparatus to efficiently store ions, fragment and analyze the ions, perform ultraviolet efficient ionization on lost neutral molecules, and then analyze the ions.

Abstract: A mass spectrometry device and analysis method for a gas phase molecule-ion reaction. The device comprises a reaction gas introduction device and a gas phase molecule-ion reaction mass spectrometry analysis device, wherein the reaction gas introduction device is connected to the gas phase molecule-ion reaction mass spectrometry analysis device; the reaction gas introduction device is configured to introduce reaction gas into the gas phase molecule-ion reaction mass spectrometry analysis device; and the gas phase molecule-ion reaction mass spectrometry analysis device is configured to enable molecules or ions to be subjected to a reaction and carry out mass spectrometry analysis on a reaction result. The reaction gas introduction device comprises a reaction gas container, the reaction gas container being configured to contain gas or volatile liquid or solid and generate gas molecules needed by a reaction; and a reaction gas quantitation device, configured to carry out flow control on the gas molecules.

Abstract: The invention discloses a networking mass analysis method and device, and belongs to the field of mass spectrometer and ion mass analysis. The device comprises an ion source, an ion transporter, an ion deflector and multiple mass analyzers, wherein the ion transporter is connected with one of the multiple mass analyzers, the multiple mass analyzers are connected with the ion deflector respectively, the ion source produces the ions to be detected, the ions to be detected enter any of the mass analyzers connected with the ion deflector via the ion transporter for mass analysis, and the remaining ions to be detected are transported to the corresponding mass analyzers via the ion deflector for mass analysis. The invention can improve the mass analysis duty ratio of continuous ion sources and obtain more mass-to-charge ratio information of ion beams within each time slot.

Abstract: The present invention discloses a rectangular ion trap device and method for ion storage. The device comprises a front end cover including left electrode, middle layer insulator, and right electrode, wherein the left electrode and the right electrode are respectively positioned at both sides of the middle layer insulator; a rear end cover, wherein the rear end cover has the same axis as the front end cover, and the central position of the rear end cover electrode is penetrated; the front and rear electrodes and the upper and lower electrodes are symmetric along the axis of the front end cover, and these electrodes form a space region for ion storage about the axis between the front end cover and the rear end cover electrode. The present invention can increase the number of ions in storage within a unit time prominently.

Abstract: The invention provides a method and device of extracting a sound source acoustic image body in 3D space. The method includes: determining a spatial position of a sound source acoustic image and determining a speaker beside the spatial position where the sound source acoustic image is located according to the determined spatial position (?, ?, ?) of the sound source acoustic image; calculating a correlation of signals of all sound tracks of the selected speaker in the horizontal direction and the vertical direction, and obtaining and storing a parameter set {ICH, ICv, Min{ICH, ICv}} of a acoustic image body, wherein the Min{ICH, ICv} is a smaller value between ICH and ICV. The expression parameters of the acoustic image body obtained in the present invention are used for providing technical support for accurately restoring the size of the sound source acoustic image in a 3D audio live system, which solves the technical problem that the restored acoustic image in a 3D audio is excessively narrow at present.

Abstract: The present invention discloses a rectangular ion trap device and method for ion storage. The device comprises a front end cover including left electrode, middle layer insulator, and right electrode, wherein the left electrode and the right electrode are respectively positioned at both sides of the middle layer insulator; a rear end cover, wherein the rear end cover has the same axis as the front end cover, and the central position of the rear end cover electrode is penetrated; the front and rear electrodes and the upper and lower electrodes are symmetric along the axis of the front end cover, and these electrodes form a space region for ion storage about the axis between the front end cover and the rear end cover electrode. The present invention can increase the number of ions in storage within a unit time prominently.

Abstract: Provided is an ion source system for an atmospheric pressure interface, comprising an atmospheric pressure ion source (1), wherein the atmospheric pressure ion source (1) is connected downstream to a vacuum ion source (2). Also provided is a mass spectrometer, using the present ion source system as an ion source. The present ion source system uses a combination of the atmospheric pressure ion source (1) and the vacuum ion source (2), is suitable for test sample having variety of forms, and performs secondary ionization on a sample to be tested, thus enhancing ion transmission efficiency. The present mass spectrometer significantly increases ion transmission efficiency, thus enabling continuous injection of samples and testing, and increasing the scanning speed of the spectrometer, particularly suitable for miniaturized mass spectrometer.

Abstract: An ion trap-based device and method for analyzing and detecting bipolar ions is provided. The device includes multiple electrodes of an ion trap; a radio frequency voltage source configured to form a radio frequency electric field; a direct current voltage source configured to form a bias electric field, positive and negative ions in the ion trap being separated by the bias electric field; a first and second detectors, configured to detect the positive and negative ions, respectively. A bipole and quadrupole field direct current voltage detection modes may be employed. A single positive ion or negative ion operation mode in a conventional biological mass spectrometry method is improved, so that the positive and negative ion modes are performed simultaneously; without any resolution loss, the analysis speed is increased, the sample consumption is reduced, and the accuracy of quantitative analysis of the samples is improved.

Abstract: The invention provides a method and device of extracting a sound source acoustic image body in 3D space. The method includes: determining a spatial position of a sound source acoustic image and determining a speaker beside the spatial position where the sound source acoustic image is located according to the determined spatial position (?, ?, ?) of the sound source acoustic image; calculating a correlation of signals of all sound tracks of the selected speaker in the horizontal direction and the vertical direction, and obtaining and storing a parameter set {ICH, ICv, Min{ICH, ICv}} of a acoustic image body, wherein the Min{ICH, ICv} is a smaller value between ICH and ICv. The expression parameters of the acoustic image body obtained in the present invention are used for providing technical support for accurately restoring the size of the sound source acoustic image in a 3D audio live system, which solves the technical problem that the restored acoustic image in a 3D audio is excessively narrow at present.

Abstract: An ion trap-based device and method for analyzing and detecting bipolar ions is provided. The device includes multiple electrodes of an ion trap; a radio frequency voltage source configured to form a radio frequency electric field; a direct current voltage source configured to form a bias electric field, positive and negative ions in the ion trap being separated by the bias electric field; a first and second detectors, configured to detect the positive and negative ions, respectively. A bipole and quadrupole field direct current voltage detection modes may be employed. A single positive ion or negative ion operation mode in a conventional biological mass spectrometry method is improved, so that the positive and negative ion modes are performed simultaneously; without any resolution loss, the analysis speed is increased, the sample consumption is reduced, and the accuracy of quantitative analysis of the samples is improved.