Abstract: Disclosed in the present disclosure is a method for preparing 16alpha-hydroxyprednisolone, belonging to the technical field of medicine preparation and processing. In the method, 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione-21-acetate is used as a starting material, and subjected to oxidation, bromo-hydroxylation, debromination and alcoholysis, so as to prepare 16alpha-hydroxyprednisolone. The method for preparing 16alpha-hydroxylprednisolone of the present disclosure can effectively control the generation of impurities in the reaction process by improving the disadvantages of traditional processes, and has a mild reaction process and a high overall conversion rate; and the method of the present disclosure has low requirements for a reaction device and low operation costs, is easy to operate, is suitable for industrial production, and has a good market prospect.

Abstract: The present disclosure provides a purification method of progesterone. In this method, aldehyde impurities in a progesterone crude product react with a sulfurated nucleophile to yield highly polar hydroxysulfonates and progesterone to realize solubility differentiation, and highly pure progesterone with a content higher than 99.5% and a total aldehyde impurities content lower than 0.2% is obtained through elutriation, filtration, washing a filter cake with water, and drying.

Abstract: Disclosed in the present disclosure is a method for preparing 16alpha-hydroxyprednisolone, belonging to the technical field of medicine preparation and processing. In the method, 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione-21-acetate is used as a starting material, and subjected to oxidation, bromo-hydroxylation, debromination and alcoholysis, so as to prepare 16alpha-hydroxyprednisolone. The method for preparing 16alpha-hydroxylprednisolone of the present disclosure can effectively control the generation of impurities in the reaction process by improving the disadvantages of traditional processes, and has a mild reaction process and a high overall conversion rate; and the method of the present disclosure has low requirements for a reaction device and low operation costs, is easy to operate, is suitable for industrial production, and has a good market prospect.

Abstract: A metal shell of an electronic device and a method for fabricating the metal shell are provided. The method for fabricating the metal shell includes: stamping out a side wall and a bottom portion of the metal shell from a metal sheet, wherein the stamping retains a reserved material at a first position on the side wall; bending and shoving the reserved material on the side wall towards an inner side of the side wall, until a protruding portion is formed at the inner side of the side wall; removing an excessive portion of the protruding portion to shape the protruding portion into a plastic gripping structure of a preset shape; and injecting and filling the plastic gripping structure with plastic.

Abstract: A metal shell of an electronic device and a method for fabricating the metal shell are provided. The method for fabricating the metal shell includes: stamping out a side wall and a bottom portion of the metal shell from a metal sheet, wherein the stamping retains a reserved material at a first position on the side wall; bending and shoving the reserved material on the side wall towards an inner side of the side wall, until a protruding portion is formed at the inner side of the side wall; removing an excessive portion of the protruding portion to shape the protruding portion into a plastic gripping structure of a preset shape; and injecting and filling the plastic gripping structure with plastic.