Patents by Inventor Youhao Dong

Youhao Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that are ERK inhibitors
    Patent number: 8546404
    Abstract: Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: October 1, 2013
    Assignee: Merck Sharp & Dohme
    Inventors: Alan B. Cooper, Yongqi Deng, Gerald W. Shipps, Jr., Neng-Yang Shih, Hugh Y. Zhu, Robert Sun, Joseph M. Kelly, Ronald J. Doll, Yang Nan, Tong Wang, Jagdish A. Desai, James J-S Wang, Youhao Dong, Vincent S. Madison, Li Xiao, Alan W. Hruza, M. Arshad Siddiqui, Ahmed A. Samatar, Sunil Paliwal, Hon-Chung Tsui, Azim Alan Celebi, Yiji Wu, Sobhana Babu Boga, Abdul-Basit Alhassan, Xiaolei Gao, Liang Zhu, Mehul Patel
  • Compounds that are ERK inhibitors
    Patent number: 7807672
    Abstract: Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substituents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: October 5, 2010
    Assignee: Schering Corporation
    Inventors: Yongqi Deng, Gerald W. Shipps, Jr., Alan Cooper, Yang Nan, Tong Wang, M. Arshad Siddiqui, Hugh Zhu, Robert Sun, Joseph M. Kelly, Ronald Doll, Jagdish Desai, James J-S Wang, Youhao Dong, Vincent Madison, Li Xiao, Alan Hruza, Neng-Yang Shih
  • Bipiperdine derivatives useful as CCR3 antagonists
    Patent number: 7705153
    Abstract: The use of CCR3 antagonists of the formula I or a pharmaceutically acceptable salt thereof for the treatment of asthma is disclosed, as well as novel compounds of the formula II, pharmaceutical compositions comprising them, and their use in the treatment of asthma, wherein R, Ra, X, Xa, R1, R2, R2a, R14, R14a, R16 and n are as defined in the specification.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: April 27, 2010
    Assignee: Schering Corporation
    Inventors: Pauline C. Ting, Jianhua Cao, Youhao Dong, Eric J. Gilbert, Ying Huang, Joseph M. Kelly, Stuart McCombie, Neng-Yang Shih
  • Novel compounds that are ERK inhibitors
    Publication number: 20090118284
    Abstract: Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
    Type: Application
    Filed: June 5, 2007
    Publication date: May 7, 2009
    Inventors: Alan B. Cooper, Yongqi Deng, Gerald W. Shipps, JR., Neng-Yang Shih, Hugh Y. Zhu, Robert Sun, Joseph M. Kelly, Ronald J. Doll, Yang Nan, Tong Wang, Jagdish A. Desai, James J-S Wang, Youhao Dong, Vincent S. Madison, Li Xiao, Alan W. Hruza, M. Arshad Siddiqui, Ahmed A. Samatar, Sunil Paliwal, Hon-Chung Tsui, Azim Alan Celebi, Yiji Wu, Sobhana Babu Boga, Abdul-Basit Alhassan, Xiaolei Gao, Liang Zhu, Mehul Patel
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Patent number: 7309704
    Abstract: The present invention relates to compounds represented by the structural Formula I: or a pharmaceutically acceptable salt thereof, which are useful for the treatment of metabolic and eating disorders such as obesity and hyperphagia, and for the treatment of diabetes and associated disorders.
    Type: Grant
    Filed: August 24, 2005
    Date of Patent: December 18, 2007
    Assignee: Schering Corporation
    Inventors: Andrew Stamford, Youhao Dong, Stuart W. McCombie, Yusheng Wu
  • Novel compounds that are ERK inhibitors
    Publication number: 20070232610
    Abstract: Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
    Type: Application
    Filed: February 13, 2007
    Publication date: October 4, 2007
    Inventors: Yongqi Deng, Gerald Shipps, Alan Cooper, Yang Nan, Tong Wang, M. Siddiqui, Hugh Zhu, Robert Sun, Joseph Kelly, Ronald Doll, Jagdish Desai, James Wang, Youhao Dong, Vincent Madison, Li Xiao, Alan Hruza, Neng-Yang Shih
  • Novel compounds that are ERK inhibitors
    Publication number: 20070191604
    Abstract: Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
    Type: Application
    Filed: December 11, 2006
    Publication date: August 16, 2007
    Inventors: Alan Cooper, Yongqi Deng, Gerald Shipps, Neng-Yang Shih, Hugh Zhu, Robert Sun, Joseph Kelly, Ronald Doll, Yang Nan, Tong Wang, Jagdish Desai, James Wang, Youhao Dong, Vincent Madison, Li Xiao, Alan Hruza, M. Siddiqui, Ahmed Samatar, Sunil Paliwal, Hon-Chung Tsui, Azim Celebi, Yiji Wu, Sobhana Boga
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Publication number: 20060030588
    Abstract: The present invention relates to compounds represented by the structural Formula I: or a pharmaceutically acceptable salt thereof, which are useful for the treatment of metabolic and eating disorders such as obesity and hyperphagia, and for the treatment of diabetes and associated disorders.
    Type: Application
    Filed: August 24, 2005
    Publication date: February 9, 2006
    Inventors: Andrew Stamford, Youhao Dong, Stuart McCombie, Yusheng Wu
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Patent number: 6982267
    Abstract: The present invention relates to compounds represented by the structural Formula I: or a pharmaceutically acceptable salt thereof, which are useful for the treatment of metabolic and eating disorders such as obesity and hyperphagia, and for the treatment of diabetes and associated disorders.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: January 3, 2006
    Assignee: Schering Corporation
    Inventors: Andrew Stamford, Youhao Dong, Stuart W. McCombie, Yusheng Wu
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Patent number: 6946476
    Abstract: The present invention relates to compounds represented by the structural Formula I: or a pharmaceutically acceptable salt thereof, which are useful for the treatment of metabolic and eating disorders such as obesity and hyperphagia, and for the treatment of diabetes and associated disorders.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: September 20, 2005
    Assignee: Schering Corporation
    Inventors: Andrew Stamford, Youhao Dong, Stuart W. McCombie, Yusheng Wu
  • Piperdine derivatives useful as CCR3 antagonists
    Publication number: 20050182095
    Abstract: The use of CCR3 antagonists of the formula I or a pharmaceutically acceptable salt thereof for the treatment of asthma is disclosed, as well as novel compounds of the formula II, pharmaceutical compositions comprising them, and their use in the treatment of asthma, wherein R, Ra, X, Xa, R1, R2, R2a, R14, R14a, R16 and n are as defined in the specification.
    Type: Application
    Filed: February 2, 2005
    Publication date: August 18, 2005
    Inventors: Pauline Ting, Jianhua Cao, Youhao Dong, Eric Gilbert, Ying Huang, Joseph Kelly, Stuart McCombie, Neng-Yang Shih
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Publication number: 20040006086
    Abstract: The present invention relates to compounds represented by the structural Formula I: 1
    Type: Application
    Filed: June 20, 2002
    Publication date: January 8, 2004
    Inventors: Andrew Stamford, Youhao Dong, Stuart W. McCombie, Yusheng Wu
  • Heteroaryl urea neuropeptide Y Y5 receptor antagonists
    Publication number: 20030055062
    Abstract: The present invention relates to compounds represented by the structural Formula I: 1
    Type: Application
    Filed: December 18, 2001
    Publication date: March 20, 2003
    Applicant: Schering Corporation
    Inventors: Andrew Stamford, Youhao Dong, Stuart W. McCombie, Yusheng Wu