Abstract: A DPP-4 inhibitor comprising a peptide represented by the formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (SEQ ID NO: 16) (wherein Xe is an amino acid residue with an isoelectric point of 5.9 to 6.3; Pro/Ala/Hyp represents Pro, Ala, or Hyp; Xa is an amino acid residue other than Hyp, Pro, and Arg, or deletion; 5 Xb is Gly, Pro, or deletion; Xc is Pro, Ala, or deletion; and Xd is an amino acid residue or deletion) as an active component. The inhibitor can be expected to bring out an effect of lowering blood glucose levels by enhancing effects of incretins; and the inhibitor may be used as a therapeutic agent for diabetes and, in addition, can act on the immune system or the like to be thus used in 10 treatment for skin diseases or the like.

Abstract: A DPP-4 inhibitor comprising a peptide represented by the formula (1): Xe-Pro/Ala/Hyp-Xa-Xb-Xc-Xd (wherein Xe is an amino acid residue with an isoelectric point of 5.9 to 6.3; Pro/Ala/Hyp represents Pro, Ala, or Hyp; Xa is an amino acid residue other than Hyp, Pro, and Arg, or deletion; Xb is Gly, Pro, or deletion; Xc is Pro, Ala, or deletion; and Xd is an amino acid residue or deletion) as an active component. The inhibitor can be expected to bring out an effect of lowering blood glucose levels by enhancing effects of incretins; and the inhibitor may be used as a therapeutic agent for diabetes and, in addition, can act on the immune system or the like to be thus used in treatment for skin diseases or the like.

Abstract: The present invention is a welded portion constitution between a first member (38) and a second member (33), comprising an inclined portion (3) provided on an end portion of at least one of the first member (38) and second member (33), and a weld bead (5) provided so as to cover at least a part of the inclined portion (3). According to the present invention, the strength of the welded joint portion can be improved without increasing the sheet thickness of the first member (38) or second member (33), and without increasing the number of components.

Abstract: The present invention is a welded portion constitution between a first member (38) and a second member (33), comprising an inclined portion (3) provided on an end portion of at least one of the first member (38) and second member (33), and a weld bead (5) provided so as to cover at least a part of the inclined portion (3). According to the present invention, the strength of the welded joint portion can be improved without increasing the sheet thickness of the first member (38) or second member (33), and without increasing the number of components.