Abstract: A motion reduction apparatus has an orthorhombic shaped floating main body (11), a plumb plate supported vertically on one side section of the floating main body by stay members (13), and flow sections (15) for flooding with incoming water are provided between the floating main body and the plumb plate in such a way that an upper end section of the plumb plate is at about the same height as the bottom surface of the floating main body.

Abstract: The compound represented by the following formula (I) and the like have PAI-1 inhibition activity; wherein: R1 represents a C6-10 aryl group which may be substituted or the like; T represents a single bond or the like; m represents 0 or 1; when m is 0, G represents —N—C(?O)—CO2H or the like; when m is 1, G represents an oxygen atom or the like; R2 represents a C6-10 aryl group which may be substituted or the like; E represents the following formula (II) wherein one of R31, R32, R33 and R34 represents the formula R1-T-, each of the other three independently represents a hydrogen atom or the like, and R35 represents the formula —X—Y?, a hydrogen atom or the like; X represents —CH2— or the like; Y? represents a carboxy group or the like; M represents a single bond or the like.

Abstract: A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, cyano group, nitro group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group and a C1-6 alkylsulfanyl group, R2 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, hydroxy group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group, a C1-6 alkylsulfanyl group and phenyl group, X represents a single bond or oxygen atom, Z represents a phenylene group or a substituted phenylene group, m represents 0 or 1.

Abstract: A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 represents a C6-10 aryl group; or a substituted C6-10 aryl group, R2 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, nitro group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group, a phenyl group and carboxy group, X represents —CH2—, —CH2CH2—, —CH?CH— or —N(R3)—C(?O)—, Y represents carboxy group or a bioisostere of carboxy group, R3 represents hydrogen atom, a C1-4 alkyl group or a C7-12 aralkyl group, m represents 0 or 1.

Abstract: A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, cyano group, nitro group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group and a C1-6 alkylsulfanyl group, R2 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, hydroxy group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group, a C1-6 alkylsulfanyl group and phenyl group, X represents a single bond or oxygen atom, Z represents a phenylene group or a substituted phenylene group, m represents 0 or 1.

Abstract: A medical balloon catheter according to the present invention includes a balloon having a groove and/or a projection helically provided relative to the longitudinal axis of the balloon. By such a structure, even after inflating the balloon once, for example, when the balloon is pushed into or removed through a severely stenosed lesion having a diameter smaller than that of the deflated balloon, the balloon can be easily wound more tightly. Therefore, pushing resistance can be reduced.

Abstract: The present invention provides a catheter which makes it possible for a biaxial type balloon catheter having a flexible structure in the joint part between a sleeve on the proximal side of the balloon and a shaft on the distal side thereof, showing no abrupt change in rigidity, reducing the step, and capable of being smoothly advanced through highly constricted and curved blood vessel portions, to be manufactured easily with a high production yield using a small number of manufacturing steps. The balloon catheter is a biaxial type for medical use, wherein only the inflation lumen of the shaft is removed from the area extending from the joint part between the shaft and the balloon sleeve on the proximal side to the distal end of the shaft, and main walls of the inflation lumen on the distal side from the joint part are formed by the proximal side balloon sleeve.

Abstract: The motion reduction apparatus improves the safety of operation of a floating body floating on water by reliably reducing motion of the floating body, and has an orthorhombic shaped floating main body (11), a plumb plate supported vertically on one side section of the floating main body by means of stay members (13), and flow sections (15) for flooding with incoming water are provided between the floating main body and the plumb plate in such a way that an upper end section of the plumb plate is at about the same height as the bottom surface of the floating main body.

Abstract: The motion reducing apparatus has an orthorhombic shaped floating main body, a horizontal plumb plate supported horizontally on one side section of the floating main body by stay members, and flow sections for flooding with incoming water are provided between the floating main body and the horizontal plate in such a way that the horizontal plate is at about the same height as the bottom surface of the floating main body.

Abstract: The motion reduction apparatus improves the safety of operation of a floating body floating on water by reliably reducing motion of the floating body, and has an orthorhombic shaped floating main body (11), a plumb plate supported vertically on one side section of the floating main body by means of stay members (13), and flow sections (15) for flooding with incoming water are provided between the floating main body and the plumb plate in such a way that an upper end section of the plumb plate is at about the same height as the bottom surface of the floating main body.

Abstract: A method for fabricating an automotive trim which is mounted with an ornamental member, in which an ornamental member which is not molded by any preliminary forming process is secured on a surface of a door trim main body with a bonding die set so as to closely follow a complicated surface profile of the door trim main body, extraneous parts of this ornamental member is cut by a thermal cutting blade attached to the bonding lower die, and the peripheral edge of the ornamental member is finished by a pressure bar.

Abstract: A device for continuously measuring and correcting a tackiness of a sheet of rubber material including a feeding unit for continuously feeding an unvulcanized rubber sheet along a flat support surface and a rotatable roller in contact with the unvulcanized rubber sheet, whereby the roller is rotated by the movement of the unvulcanized rubber sheet, and entrained in the sheet feed direction due to a tackiness of the unvulcanized rubber sheet. A load cell is connected to the roller via a linkage, for measuring a resistance to the rolling of the roller, i.e., a change of a position of the roller entrained in the sheet feed direction.

Abstract: Rubber compositions for tire treads of an all-weather type are disclosed which are so designed as to exhibit high dynamic Young's modulus, sufficient resistance to snow and ice skidding, to abrasion, to cracking and to crack growth and adequate durability. A selected base rubber is combined with a selected carbon black and a selected m-cresol resin. The base rubber is a blend of two different rubbers, one being natural rubber alone or a combination with a diene rubber and the other being butadiene rubber. The carbon black has specified absorptivity of iodine and dibutyl phthalate. The m-cresol resin is a novolak condensate.

Abstract: Tread rubber compositions or use in automobile tires are disclosed which essentially comprise matrix rubbers and specified amounts of a selected class of low-hardness vulcanized rubbers having specified particle sizes. The matrix and vulcanized rubbers include carbon black, respectively, in amounts defined by the equation 0<X.ltoreq.Y/3 where X is the amount of carbon black present in the vulcanized rubber, and Y is the amount of carbon black in the matrix rubber, each such amount being based on the total weight of the matrix rubber. The resulting tire is rendered highly resistant to snowy and icy conditions and also to abrasive wear.