Patents by Inventor Youn Soo Sohn

Youn Soo Sohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof
    Publication number: 20040219127
    Abstract: Disclosed are a new class of a polyphosphazene-platinum(II) conjugate antitumor agent having high tumor tissue selectivity due to its enhanced permeability and retention effect to tumor tissues, and a preparation method thereof: 1
    Type: Application
    Filed: January 7, 2004
    Publication date: November 4, 2004
    Applicant: Ewha Womans University
    Inventors: Youn Soo Sohn, Yong Joo Jun, Joo Ik Kim
  • Platinum(II) complexes of N-substituted amino dicarboxylates and the preparation method thereof
    Publication number: 20040162342
    Abstract: Disclosed are a platinum (II) complex of N-substituted amino dicarboxylate showing antitumor activity represented by the following formula (1) and a preparation method thereof: 1
    Type: Application
    Filed: January 8, 2004
    Publication date: August 19, 2004
    Applicant: Board of Trustees, EWHA Womans University
    Inventors: Youn Soo Sohn, Yeong-Sang Kim, Rita Song
  • Thermosensitive cyclotriphosphazene derivatives and a preparation method thereof
    Patent number: 6417383
    Abstract: The present invention relates to novel cyclotriphosphazene derivatives represented by Formula (1) and a preparation method thereof wherein HNA is an amino acid group selected from glycine group(—NHCH2COO−), aminomalonic acid group(—NHCH(COO−)2), aspartic acid group (—NHCH(CH2COO−)COO−) and glutamic acid group (—NHCH(CH2CH2COO−)COO−), m is a repeating unit of poly(alkoxyethyleneglycol) selected from 2, 7, 12 and 16, and n is an integer representing number of alkyl carbons and selected from 0, 1, and 3.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: July 9, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Soo-Chang Song, Sang Beom Lee
  • Thermosensitive cyclotriphosphazene-platinum complex conjugate, its preparation method and anticancer agent containing the same
    Patent number: 6333422
    Abstract: The present invention provides a novel thermosensitive cyclotriphosphazene-platinum complex conjugates represented by Formula 1, wherein m is a repeating unit of poly(alkoxyethylene glycol) selected from the integers 2, 7 and 12; n represents the length of the alkyl chain selected from the integers 0, 1, 2 and 3; x represents the length of the anionic amino acid residue selected from the integers 0 (amino malonic acid derivatives), 1 (aspartic acid derivatives) and 2 (glutamic acid derivatives); A2 is a bidentate chelating diamine selected from the group consisting of 2,2-dimethyl-1,3-propanediamine (dmpda), trans(±)-1,2-diaminocyclohexane (dach) and 1,1-diaminomethylcyclohexane (dmach).
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: December 25, 2001
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Soo-Chang Song, Sang Beom Lee
  • Biodegradable and thermosensitive polyphosphazenes and their preparation method
    Patent number: 6319984
    Abstract: The present invention relates to novel biodegradable polyphosphazenes represented by Formula 1 and a preparation method thereof. Polyphosphazenes of the present invention not only have thermosensitivity and biodegradability simultaneously, but also their phase transition temperature and degradation rate can be controlled.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: November 20, 2001
    Assignee: Korea Institute of Science and Technology
    Inventors: Soo-Chang Song, Youn Soo Sohn, Bae Hoon Lee, Sang Beom Lee
  • Platinum complex conjugated to cyclotriphosphazene, its preparation, and anticancer agent comprising the same
    Patent number: 6221906
    Abstract: The present invention relates to a platinum complex conjugated to a cyclotriphosphazene represented by Formula 1 and a preparation method thereof. The platinum complex according to the present invention can be used as an anticancer agent.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: April 24, 2001
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Hyoung Gee Baek, Chong Ock Lee
  • Anticancer (IV) complexes for oral administration and a method of making the same
    Patent number: 5998648
    Abstract: Platinum (IV) complexes for oral administration represented by the structural formula ##STR1## where A--A is a symmetrical diamine that can chelate to platinum and is selected from the group consisting of ethylene diamine, t(.+-.)-1,2-diaminocyclohexane, 2,2-dimethyl-1,3-propanediamine, cyclohexane-1,1-dimethaneamine and tetrahydro-4H-pyran-4,4-dimethaneamine; and R is propionyl, butyryl or valeryl. These complexes are useful in the treatment of cancer.
    Type: Grant
    Filed: August 14, 1998
    Date of Patent: December 7, 1999
    Assignee: Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Sung Sil Lee, Young-A Lee, Kwan Mook Kim, Chong Ock Lee
  • Polymeric platinum complex, preparation thereof, and anticancer agent comprising thereof
    Patent number: 5665343
    Abstract: A novel polymeric platinum complex represented by the following formula (I): ##STR1## wherein, S, A, x, m and n are defined as above, a process for preparation thereof, and the use thereof as an anticancer agent.
    Type: Grant
    Filed: January 2, 1996
    Date of Patent: September 9, 1997
    Assignees: Il-Yang Pharm. Co., Ltd, Korea Institute of Science and Technology
    Inventors: Youn Soo Sohn, Hyounggee Baek, Yang Ha Cho, Ok-Sang Jung