Abstract: Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Abstract: The present invention relates to a transposon vector, a transposon system comprising same, a transposon kit, a cell into which the transposon vector is inserted, and uses thereof, wherein the present invention has been completed by confirming that an exogenous gene is effectively transferred into the chromosome of a target cell to produce a high yield of genetically modified cells. In particularly, it was confirmed that the transposon according to the present invention can effectively transfer a TCR or CAR-encoding gene to immune cells, and cells expressing the TCR or CAR show high reactivity to an antigen, and thus, it is expected that various TCR-T cells and CAR-T cells can be produced by using the transposon system according to the present invention.

Abstract: A light emitting element includes a first semiconductor layer including a first type of semiconductor, the first semiconductor layer including a 1-1-th semiconductor layer and a 1-2-th semiconductor layer, which are arranged in a length direction of the light emitting element; a second semiconductor layer including a second type of semiconductor different from the first type; an active layer disposed between the 1-2-th semiconductor layer and the second semiconductor layer; and an intermediate layer disposed between the 1-1-th semiconductor layer and the 1-2-th semiconductor layer and having a porous structure.

Abstract: Provided are a piperidine derivative compound, a hydrate thereof, a solvate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for the prevention or treatment of diseases related to autotaxin activity, comprising same as an active ingredient, in which the piperidine derivative compound exhibits excellent inhibitory activity against autotaxin, and thus can be effectively used in the treatment and prevention of diseases related to autotaxin inhibition, such as fibrotic diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, metabolic diseases, cancer and cancer metastasis, ocular diseases, cholestatic form and other forms of chronic pruritus, and acute or chronic organ transplant rejection.

Abstract: The present disclosure relates to a biomarker for diagnosis of oral cancer, using metabolite profiling and, more specifically, to a biomarker composition containing an acyl carnitine metabolite which varies in quantity upon the onset of oral cancer, and a diagnostic method for oral cancer, using same. The present disclosure allows for the early diagnosis of oral cancer which has been conventionally difficult to diagnose due to the impossible tissue biopsy thereof, and can reduce the pain and risk burden of patients because it uses a liquid biopsy method in which a blood sample is collected and analyzed.

Abstract: A method for producing an immune cell composition is disclosed. The method includes steps of: (a) culturing a tumor sample in a first container, (b) obtaining a first immune cell population from the cultured product obtained from (a); (c) seeding a second composition and a second immune cell population in a second container; (d) expending the second immune cell population to produce a third immune cell population; and (e) obtaining the third immune cell population from the expanded product obtained from (d) and producing the immune cell composition.

Abstract: Disclosed is a method of producing Tc-99m by using nuclear resonance fluorescence. More specifically, and a method of preparing Tc-99m by using nuclear resonance fluorescence includes irradiating a ground-state Tc-99 nucleus with a photon beam, thereby causing a nuclear transmutation to proceed such that the nucleus excited to high energy and then undergoes a transition to Tc-99m.

Abstract: Disclosed is an apparatus for extracting multiple laser Compton scattering (“LCS”) photon beams using a laser Compton scattering reaction, the apparatus including: a linear accelerator for accelerating an electron beam; and an LCS gamma ray generation module including an LCS gamma ray generator for irradiating a target with an LCS gamma ray generated by emitting laser light to an electron beam released from the linear accelerator and a bending magnet for adjusting a direction of the electron beam passed through the LCS gamma ray generator, wherein at least two LCS gamma ray generation modules are sequentially arranged to form a closed loop together with the linear accelerator.

Abstract: A system and method for mobility in a wireless network are presented. A user equipment with a processor configured to inform a network component of a closed subscriber group (CSG) capability of the UE. The processor informs the network component during capability exchange signaling. The processor informs the network component whether the UE is capable of detecting a CSG cell and whether the UE is a member of at least one CSG.

Abstract: Disclosed is a method of producing Tc-99m by using nuclear resonance fluorescence. More specifically, the method of producing Tc-99m by using nuclear resonance fluorescence includes irradiating a ground-state Tc-99 nucleus with a photon beam, thereby causing a nuclear transmutation to proceed such that the nucleus is excited to high energy and then undergoes a transition to Tc-99m.

Abstract: Disclosed is an apparatus for extracting multiple laser Compton scattering photon (“LCS”) beams using a laser Compton scattering reaction, the apparatus including: a linear accelerator for accelerating an electron beam; and an LCS gamma ray generation module including an LCS gamma ray generator for irradiating a target with an LCS gamma ray generated by emitting laser light to an electron beam released from the linear accelerator and a bending magnet for adjusting a direction of the electron beam passed through the LCS gamma ray generator, wherein at least two LCS gamma ray generation modules are sequentially arranged to form a closed loop together with the linear accelerator.

Abstract: A device for providing a realistic media content, includes: inward facing image acquisition unit configured to acquire multiple inward facing images that are taken by an inward method using multiple cameras arranged around an object; an outward facing image acquisition unit configured to acquire multiple outward facing images that are taken by an outward method using the multiple cameras arranged around a point; a background image generation unit configured to generate a 360° cylindrical image by stitching the multiple outward facing images and then convert the 360° cylindrical image into a 360° spherical image to generate a background image; a 3D object reconstruction unit configured to extract a region of the object from the multiple inward facing images to generate a 3D object; and a combined image transmission unit configured to combine the background image with the 3D object and transmit the combined image to a display device.

Abstract: Disclosed is a guitar with a replaceable soundbox. The guitar with a replaceable soundbox according to the present invention comprises: a soundbox; a neck having a neck hill that protrudes therefrom and is detachably coupled to one side of the soundbox, and having a plurality of strings disposed to hold chords in accordance with a scale and harmony; a bridge detachably coupled to the soundbox such that one end of the plurality of strings is fixed; a playing part including a head extended to the neck such that the other end of the plurality of strings is fixed; and an adjustment part, coupled on the head, for adjusting the tension of the plurality of strings to increase or decrease.

Abstract: A method to transfer control is presented. The method includes receiving a request to transfer control of a collaborative session from a first user equipment (UE). The method includes sending a request for the transfer of control of the collaborative session in response to the received request to a second UE, and receiving, in response to the sent request to the second UE, an indication of acceptance of the transfer of control of the collaborative session. The method includes sending a notification of status to the first UE of the control of the collaborative session in response to receiving, from the second UE, the indication of acceptance.

Abstract: A device for providing a realistic media content, includes: inward facing image acquisition unit configured to acquire multiple inward facing images that are taken by an inward method using multiple cameras arranged around an object; an outward facing image acquisition unit configured to acquire multiple outward facing images that are taken by an outward method using the multiple cameras arranged around a point; a background image generation unit configured to generate a 360° cylindrical image by stitching the multiple outward facing images and then convert the 360° cylindrical image into a 360° spherical image to generate a background image; a 3D object reconstruction unit configured to extract a region of the object from the multiple inward facing images to generate a 3D object; and a combined image transmission unit configured to combine the background image with the 3D object and transmit the combined image to a display device.

Abstract: Disclosed is a guitar with a replaceable soundbox. The guitar with a replaceable soundbox according to the present invention comprises: a soundbox; a neck having a neck hill that protrudes therefrom and is detachably coupled to one side of the soundbox, and having a plurality of strings disposed to hold chords in accordance with a scale and harmony; a bridge detachably coupled to the soundbox such that one end of the plurality of strings is fixed; a playing part including a head extended to the neck such that the other end of the plurality of strings is fixed; and an adjustment part, coupled on the head, for adjusting the tension of the plurality of strings to increase or decrease.

Abstract: A system and method for mobility in a wireless network are presented. A user equipment with a processor configured to inform a network component of a closed subscriber group (CSG) capability of the UE. The processor informs the network component during capability exchange signaling. The processor informs the network component whether the UE is capable of detecting a CSG cell and whether the UE is a member of at least one CSG.

Abstract: A system and method for mobility in a wireless network are presented. A user equipment with a processor configured to inform a network component of a closed subscriber group (CSG) capability of the UE. The processor informs the network component during capability exchange signaling. The processor informs the network component whether the UE is capable of detecting a CSG cell and whether the UE is a member of at least one CSG.

Abstract: A user equipment (UE) including one or more processors configured to cause the UE to prepare to reselect to a macro cell responsive to the UE placing an emergency call in a femtocell, wherein preparing to reselect is performed in addition to placing the emergency call.

Abstract: A system and method for mobility in a wireless network are presented. A user equipment with a processor configured to inform a network component of a closed subscriber group (CSG) capability of the UE. The processor informs the network component during capability exchange signaling. The processor informs the network component whether the UE is capable of detecting a CSG cell and whether the UE is a member of at least one CSG.