Patents by Inventor Young-Ah Shin
Young-Ah Shin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200160935Abstract: A cloud-based gene analysis service platform includes: a communication module configured to communicate with a terminal connected to a laboratory; a controller configured to monitor generation of information on a genome corresponding to an individual through the communication module; and a storage unit configured to encrypt and store the generated information on the genome, wherein the controller performs analysis on the basis of the information on the genome and personal phenotypic information. Accordingly, it is possible to effectively protect gene information and provide individual customized service.Type: ApplicationFiled: December 21, 2018Publication date: May 21, 2020Inventors: Young Ah SHIN, Seung Bum SEO, Phil Sun SHIN
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Patent number: 10155763Abstract: The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-? (TGF-?) type I receptor (ALK5) and/or the activin type I receptor (ALK4); a pharmaceutical composition comprising same as an active ingredient; and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.Type: GrantFiled: July 13, 2012Date of Patent: December 18, 2018Assignee: TIUMBIO CO., LTD.Inventors: Ju Young Lee, Keun-Ho Ryu, Jae-Sun Kim, Yong-Hyuk Kim, Dong-Chul Shin, Bong-yong Lee, Sang-hwan Kang, Hyun-Jung Lee, Hoechul Jung, Young Ah Shin, Euisun Park, Jaeseung Ahn, Hun-Taek Kim, Je Ho Ryu
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Patent number: 9481684Abstract: Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.Type: GrantFiled: February 28, 2013Date of Patent: November 1, 2016Assignee: SK CHEMICALS CO., LTD.Inventors: Seon-Mi Kim, Jae-Sun Kim, Minhee Lee, So-young Lee, Bong-yong Lee, Young-Ah Shin, Euisun Park, Jung A Lee, Min-Young Han, Jaeseung Ahn, Taekyung Yoo, Hun-Taek Kim
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Patent number: 9096571Abstract: Provided are picolinamide and pyrimidine-4-carboxamide compounds, a method for preparing the same, a pharmaceutical composition containing the same, and a medical use using the compound as an agent for preventing, regulating, and treating diseases related to regulation of glucocorticoids by using selective inhibitory activity of the compound for an 11?-HSD1 enzyme. The picolinamide and pyrimidine-4-carboxamide compounds of the present invention are selective inhibitors of human-derived 11?-HSD1 enzymes, and are useful in an agent for preventing, regulating, and treating diseases related to glucocorticoid regulation in which human-derived 11?-HSD1 enzymes are involved, for example, metabolic syndromes such as, type 1 and type 2 diabetes, diabetes later complications, latent autoimmune diabetes adult (LADA), insulin tolerance syndromes, obesity, impaired glucose tolerance (IGT), impaired fasting glucose (IFG), damaged glucose tolerance, dyslipidemia, atherosclerosis, hypertension, etc.Type: GrantFiled: May 4, 2011Date of Patent: August 4, 2015Assignee: SK CHEMICALS CO., LTD.Inventors: Je Ho Ryu, Shin Ae Kim, Keun Ho Ryu, Jae Sun Kim, Nam Ho Kim, Hye Young Han, Yong Hyuk Kim, Won-No Youn, Yoon-Jung Lee, Hyun Joo Son, Bong-Yong Lee, Sung Hoon Park, Ju Young Lee, Hyun Jung Lee, Hoe Chul Jung, Young Ah Shin, Jung A Lee, Bo Ram Lee, Joon Ho Sa
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Publication number: 20150166558Abstract: Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.Type: ApplicationFiled: February 28, 2013Publication date: June 18, 2015Applicant: SK CHEMICALS CO., LTD.Inventors: Seon-Mi Kim, Jae-Sun Kim, Minhee Lee, So-young Lee, Bong-Yong Lee, Young Ah Shin, Euisun Park, Jung A Lee, Min-Young Han, Jaeseung Ahn, Taekyung Yoo, Hun-Taek Kim
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Patent number: 8513277Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: November 15, 2011Date of Patent: August 20, 2013Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Sun-Young Jang
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Publication number: 20130210811Abstract: Provided are picolinamide and pyrimidine-4-carboxamide compounds, a method for preparing the same, a pharmaceutical composition containing the same, and a medical use using the compound as an agent for preventing, regulating, and treating diseases related to regulation of glucocorticoids by using selective inhibitory activity of the compound for an 11?-HSD1 enzyme. The picolinamide and pyrimidine-4-carboxamide compounds of the present invention are selective inhibitors of human-derived 11?-HSD1 enzymes, and are useful in an agent for preventing, regulating, and treating diseases related to glucocorticoid regulation in which human-derived 11?-HSD1 enzymes are involved, for example, metabolic syndromes such as, type 1 and type 2 diabetes, diabetes later complications, latent autoimmune diabetes adult (LADA), insulin tolerance syndromes, obesity, impaired glucose tolerance (IGT), impaired fasting glucose (IFG), damaged glucose tolerance, dyslipidemia, atherosclerosis, hypertension, etc.Type: ApplicationFiled: May 4, 2011Publication date: August 15, 2013Applicant: SK CHEMICALS CO., LTD.Inventors: Je Ho Ryu, Shin Ae Kim, Keun Ho Ryu, Jae Sun Kim, Nam Ho Kim, Hye Young Han, Yong Hyuk Kim, Won-No Youn, Yoon-Jung Lee, Hyun Joo Son, Bong-Yong Lee, Sung Hoon Park, Ju Young Lee, Hyun Jung Lee, Hoe Chul Jung, Young Ah Shin, Jung A Lee, Bo Ram Lee, Joon Ho Sa
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Publication number: 20130018052Abstract: The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-? (TGF-?) type I receptor (ALK5) and/or the activin type I receptor (ALK4); a pharmaceutical composition comprising same as an active ingredient; and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.Type: ApplicationFiled: July 13, 2012Publication date: January 17, 2013Applicant: SK CHEMICALS CO., LTD.Inventors: Ju Young LEE, Keun-Ho RYU, Jae-Sun KIM, Yong-Hyuk KIM, Dong Chul SHIN, Bong-yong LEE, Sang-hwan KANG, Hyun-Jung LEE, Hoechul JUNG, Young Ah SHIN, Euisun PARK, Jaeseung AHN
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Patent number: 8148529Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: GrantFiled: September 3, 2005Date of Patent: April 3, 2012Assignee: Yuhan CorporationInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Ryong Choi, Sun-Young Jang, legal representative
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Publication number: 20120065224Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: November 15, 2011Publication date: March 15, 2012Applicant: YUHAN CORPORATIONInventors: Jae-Gyu KIM, Byung-Nak AHN, Hyouk-Woo LEE, Suk-Won YOON, Young-Ae YOON, Dong-Hoon KIM, Se-Hoon KEUM, Young-Ah SHIN, Heui-Il KANG, Ryong CHOI, Sun-Young JANG
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Publication number: 20100063041Abstract: The present invention provides a novel phenylpropionic acid derivative and a PPAR-? modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-? and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.Type: ApplicationFiled: March 7, 2008Publication date: March 11, 2010Inventors: Ho-Sang Moon, Moo-Hi Yoo, Soon-Hoe Kim, Joong-In Lim, Moon-Ho Son, Mi-Kyung Kim, Chang-Yell Shin, Jin-Kwan Kim, Sang-Kuk Park, Yu-Na Chae, Hyun-Joo Shim, Sun-Ho Jeon, Hae-Sun Kim, Gil-Tae Wie, Dong-Hwan Kim, Byung-Kyu Lee, Chan-Sun Park, Byung-Nak Ahn, Eunkyung Kim, Myung-Ho Bae, Young-Ah Shin, Youn Hur, Chun-Ho Lee, Hyun-Ho Choi, Bongtae Kim, Wonee Chong
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Publication number: 20090005409Abstract: The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.Type: ApplicationFiled: September 3, 2005Publication date: January 1, 2009Applicant: YUHAN CORPORATIONInventors: Jae-Gyu Kim, Byung-Nak Ahn, Hyouk-Woo Lee, Suk-Won Yoon, Young-Ae Yoon, Dong-Hoon Kim, Se-Hoon Keum, Young-Ah Shin, Heui Il Kang, Ryong Choi, Sun-Young Jang
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Patent number: 5849753Abstract: Substituted pyridyl imidazole derivatives of formula (I) inhibit effectively the action of angiotensin II and have a superior anti-hypertensive activity.Type: GrantFiled: July 25, 1996Date of Patent: December 15, 1998Assignee: Korea Research Institute of Chemical TechnologyInventors: Sung-Eun Yoo, Kyu-Yang Yi, Sang-Hee Lee, Hye-Ryung Kim, Jee-Hee Suh, Nak-Jeong Kim, Seon-Ju Kim, Ok-Ja Cha, Young-Ah Shin, Wha-Sup Shin, Sung-Hou Lee, Yi-Sook Jung, Byung-Ho Lee, Ho-Won Seo
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Patent number: 5691348Abstract: Novel pyridyl imidazole derivatives of formula(I) inhibit effectively the action of angiotensin II and have a superior antihypertensive activity: ##STR1## wherein: A is a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl or alkenyl group, OR.sup.1 (wherein R.sup.1 is a hydrogen, or a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl or alkenyl radical), or NR.sup.2 R.sup.3 (wherein R.sup.2 and R.sup.3 are independently a hydrogen, or a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl radical);B is a group of the following formula ##STR2## D is a hydrogen; a halogen; a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl or C.sub.2 -C.sub.6 alkynyl group which is optionally substituted with OH, a C.sub.1 -C.sub.4 alkoxy radical, CO.sub.2 R.sup.1, COR.sup.1, CON(R.sup.1).sub.2 or N(R.sup.1).sub.2, wherein R.sup.1 is the same as defined above; tetrazol-5-yl; a perfluoro-C.sub.1 -C.sub.4 alkyl group; or N(R.sup.1).sub.2, OR.sup.1, CO.sub.2 R.sup.1 or CON(R.sup.1).sub.2, wherein R.Type: GrantFiled: December 8, 1996Date of Patent: November 25, 1997Assignee: Daewoo Electronics Co., Ltd.Inventors: Sung-Eun Yoo, Kyu-Yang Yi, Sang-Hee Lee, Hye-Ryung Kim, Jee-Hee Suh, Nak-Jeong Kim, Seon-Ju Kim, Ok-Ja Cha, Young-Ah Shin, Wha-Sup Shin, Sung-Hou Lee, Yi-Sook Jung, Byung-Ho Lee, Ho-Won Seo, Hye-Suk Lee
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Patent number: 5665738Abstract: Novel imidazole derivatives of formula(I) inhibit effectively the action of angiotensin II and have a superior antihypertensive activity: ##STR1## wherein: A is a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl group, or OR.sub.1 wherein R.sub.1 is a hydrogen, or a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl radical; B is a halogen, CF.sub.3 or CF.sub.2 CF.sub.3 ; X is N or N-oxide; Y is --CH.sub.2 --, --CH(OR.sub.1)-- wherein R.sub.1 is the same as defined above, or --C(.dbd.O)--; n is 0 or an integer of 1 to 4; Z is a halogen, --OH, --OR.sub.1, --NR.sub.1 R.sub.2, --N(.dbd.O)R.sub.3 R.sub.4, --C(.dbd.O)R.sub.1, --C(.dbd.O)OR.sub.1, --CH(OR.sub.1).sub.2 or --C(.dbd.O)N.sub.1 N.sub.2 wherein R.sub.1 is the same as defined above, R.sub.2 is, independently of R.sub.1, a hydrogen, or a straight, branched or cyclic C.sub.1 -C.sub.6 alkyl radical, and R.sub.3 and R.sub.4 are independently a straight, branched or cyclic C.sub.1 -C.sub.Type: GrantFiled: November 13, 1996Date of Patent: September 9, 1997Assignee: Korea Research Institute of Chemical TechnologyInventors: Sung-Eun Yoo, Kyu-Yang Yi, Sang-Hee Lee, Hye-Ryung Kim, Jee-Hee Suh, Nak-Jeong Kim, Seon-Ju Kim, Ok-Ja Cha, Young-Ah Shin, Wha-Sup Shin, Sung-Hou Lee, Yi-Sook Jung, Byung-Ho Lee, Ho-Won Seo, Hye-Suk Lee