Patents by Inventor Young Bock Shim
Young Bock Shim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9511172Abstract: Provided is a method of manufacturing an allogeneic soft-tissue transplant having autologous stem cells transplanted therein using an allogeneic soft-tissue support that is obtained from an allogeneic organism. In this regard, an allogeneic soft-tissue transplant that can replace a damaged soft-tissue of a human body is manufactured.Type: GrantFiled: February 24, 2012Date of Patent: December 6, 2016Assignee: Cellumed Co., Ltd.Inventors: Young Bock Shim, Kwang Il Lee, Ju Woong Jang, Jung Soo Lee
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Publication number: 20150209476Abstract: Provided is a method of manufacturing an allogeneic soft-tissue transplant having autologous stem cells transplanted therein using an allogeneic soft-tissue support that is obtained from an allogeneic organism. In this regard, an allogeneic soft-tissue transplant that can replace a damaged soft-tissue of a human body is manufactured.Type: ApplicationFiled: February 24, 2012Publication date: July 30, 2015Applicant: CELLUMED CO., LTD.Inventors: Young Bock Shim, Kwang ll Lee, Ju Woong Jang, Jung Soo Lee
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Patent number: 8648178Abstract: The present invention relates to a method for purifying a protein belonging to the TGF-?, superfamily, preferably BMP, and more preferably BMP-2. According to the invention, the number of purification steps is reduced and the purification process is simplified, compared to the conventional BMP-2 purification method. Thus, the time required for purification can be shortened and the cost can be reduced. In addition, the invention solves the problem that as the time for purification increases and the number of purification steps increases, BMP-2 is degraded by protease or lost during purification steps, resulting in a decrease in the final yield of BMP-2. Thus, the invention increases the final yield of BMP-2.Type: GrantFiled: May 12, 2010Date of Patent: February 11, 2014Assignee: Korea Bone Bank Co., Ltd.Inventors: Young-Bock Shim, Yeong-Schick Kim, Yon-Rak Choi, Ju-Woong Jang
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Patent number: 8431623Abstract: The present invention relates to a process for forming a porous poly(vinyl alcohol) (PVA) scaffold using a pore-forming agent, comprising: mixing PVA with the pore-forming agent to form micropores in the PVA scaffold and using an easily decomposable pore-forming agent after the formation of the pores to improve convenience and reduce the processing time in manufacturing the porous PVA scaffold as well as to enable a pore size and porosity to be selected. A process for forming a porous PVA scaffold using a pore-forming agent according to the present invention includes heating to melt the PVA, cooling the melted PVA and mixing the PVA with a heat-decomposable pore-forming agent, repeating the freezing/thawing of the mixed PVA to cure the PVA mixture, and stirring the cured PVA mixture with a hydrochloric acid solution at a high temperature of 65° C. or more to produce foam.Type: GrantFiled: May 10, 2010Date of Patent: April 30, 2013Assignee: Korea Bone Bank Co., Ltd.Inventors: Young-Bock Shim, Hong-Hee Jung, Yon-Rak Choi, Ju-Woong Jang
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Patent number: 8409623Abstract: A cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute are provided, and more particularly, a cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute by which defatting, demineralizing, cleaning, and sterilizing processes are performed within a short time using a supersonic cabitation without damaging a surface and an inside of a bone tissue so as to further rapidly, effectively supply an allogeneic or xenogeneic bone graft substitute. Internal and external concentrations of Ca++ of the allogeneic or xenogeneic bone graft substitute are effectively removed so as to maintain physical properties of the allogenetic or xenogeneic bone graft substitute.Type: GrantFiled: January 23, 2009Date of Patent: April 2, 2013Assignee: Korea Bone Bank, Inc.Inventors: Young Bock Shim, Ju Woong Jang, Hyang Kim, Kwang Il Lee, Keun Soo Lee, Il Hwan Kim
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Publication number: 20130060012Abstract: The present invention relates to a method for purifying a protein belonging to the TGF-?, superfamily, preferably BMP, and more preferably BMP-2. According to the invention, the number of purification steps is reduced and the purification process is simplified, compared to the conventional BMP-2 purification method. Thus, the time required for purification can be shortened and the cost can be reduced. In addition, the invention solves the problem that as the time for purification increases and the number of purification steps increases, BMP-2 is degraded by protease or lost during purification steps, resulting in a decrease in the final yield of BMP-2. Thus, the invention increases the final yield of BMP-2.Type: ApplicationFiled: May 12, 2010Publication date: March 7, 2013Applicant: KOREA BONE BANK CO., LTD.Inventors: Young - Bock Shim, Yeong - Schick Kim, Yon - Rak Choi, Ju - Woong Jang
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Publication number: 20120108689Abstract: The present invention relates to a process for forming a porous poly(vinyl alcohol) (PVA) scaffold using a pore-forming agent, and more particularly, to a process for forming a porous PVA scaffold using a pore-forming agent, comprising: mixing PVA with the pore-forming agent to form micropores in the PVA scaffold and using an easily decomposable pore-forming agent after the formation of the pores to improve convenience and reduce the processing time in manufacturing the porous PVA scaffold as well as to enable a pore size and porosity to be selected. A process for forming a porous PVA scaffold using a pore-forming agent according to the present invention includes heating to melt the PVA, cooling the melted PVA and mixing the PVA with a heat-decomposable pore-forming agent, repeating the freezing/thawing of the mixed PVA to cure the PVA mixture, and stirring the cured PVA mixture with a hydrochloric acid solution at a high temperature of 65° C. or more to produce foam.Type: ApplicationFiled: May 10, 2010Publication date: May 3, 2012Applicant: KOREA BONE BANK CO., LTD.Inventors: Young-Bock Shim, Hong-Hee Jung, Yon-Rak Choi, Jui-Woong Jang
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Patent number: 8080036Abstract: A pedicle screw is provided to be inserted into and fixed to a pedicle of a spinal disease patient, and more particularly, a pedicle screw in which a screw thread of a clamp screw is formed to have dents and protrusions with trapezoid cross-sections so as to form a predetermined gap with a screw thread of a fixing unit having dents and protrusions with rectangular cross-sections when the clamp screw is combined with the fixing unit, and the screw thread of the clamp screw has different pitches to disperse an external impact so as to further firmly combine the clamp screw with the fixing unit.Type: GrantFiled: January 23, 2009Date of Patent: December 20, 2011Assignee: Korea Bone Bank, Inc.Inventors: Young Bock Shim, Ju Woong Jang, Dae Kwan Kim, Sok Kyun Hong
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Publication number: 20100166879Abstract: A cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute are provided, and more particularly, a cancellous bone graft substitute and a method of manufacturing the cancellous bone graft substitute by which defatting, demineralizing, cleaning, and sterilizing processes are performed within a short time using a supersonic cabitation without damaging a surface and an inside of a bone tissue so as to further rapidly, effectively supply an allogeneic or xenogeneic bone graft substitute. Internal and external concentrations of Ca++ of the allogeneic or xenogeneic bone graft substitute are effectively removed so as to maintain physical properties of the allogenetic or xenogeneic bone graft substitute.Type: ApplicationFiled: January 23, 2009Publication date: July 1, 2010Applicant: KOREA BONE BANK, INC.Inventors: Young Bock Shim, Ju Woong Jang, Hyang Kim, Kwang Il Lee, Keun Soo Lee, Il Hwan Kim
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Publication number: 20100094353Abstract: A pedicle screw is provided to be inserted into and fixed to a pedicle of a spinal disease patient, and more particularly, a pedicle screw in which a screw thread of a clamp screw is formed to have dents and protrusions with trapezoid cross-sections so as to form a predetermined gap with a screw thread of a fixing unit having dents and protrusions with rectangular cross-sections when the clamp screw is combined with the fixing unit, and the screw thread of the clamp screw has different pitches to disperse an external impact so as to further firmly combine the clamp screw with the fixing unit.Type: ApplicationFiled: January 23, 2009Publication date: April 15, 2010Applicant: KOREA BONE BANK, INC.Inventors: Young Bock Shim, Ju Woong Jang, Dae Kwan Kim, Sok Kyun Hong
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Publication number: 20100028430Abstract: Disclosed are a bioactive protein-calcium phosphate ceramic composite for surface modification of a substrate for use as a substitute in the treatment of musculoskeletal disorders, and a preparation method thereof. The bioactive protein-calcium phosphate ceramic composite is prepared by mixing an aqueous solution of calcium phosphate and a protein, and impregnating the calcium phosphate and the protein in the resulting aqueous solution to co-precipitate them on a substrate, such as metals, ceramics and polymers, wherein the substrate is patterned, and different proteins are impregnated in at least two regions of the patterned regions.Type: ApplicationFiled: July 22, 2006Publication date: February 4, 2010Applicant: Korea Bone Bank Co., Ltd.Inventors: Ju Woong Jang, Kwang II Lee, Hyang Kim, Young Bock Shim, Hyun Min Kim