Abstract: Disclosed are quinoline and quinazoline compounds which modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and genitourinary system. Preferred compounds include quinoline or quinazoline derivatives substituted at the 4-position via N(H), C(O) or O moieties.

Abstract: An apparatus may include a device comprising a controller configured to perform, using a first namespace identifier, a first access of a namespace of the device, wherein the device may be configured to perform, using a second namespace identifier, a second access of the namespace of the device, and wherein the second namespace identifier may include first information to determine the first namespace identifier, and second information to identify the controller. The first information may include the first namespace identifier, and the second information may include a controller identifier for the controller. The second namespace identifier may include the first namespace identifier concatenated with the controller identifier. The controller may include at least a portion of a communication endpoint. The device may further include a second controller configured to perform the second access. The first controller may include a child controller, and the second controller may include a parent controller.

Abstract: The disclosed computer-implemented method may include systems for generating personalized avatar reactions during live video broadcasts. For example, the systems and methods described herein can access a social networking system user's profile to identify an avatar associated with the social networking system user. The systems and methods can generate an avatar reaction by modifying one or more features of the avatar based on a corresponding emoticon reaction. Once generated, the social networking system user can select the avatar reaction for addition to an ephemeral reaction stream associated with a live video broadcast. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Embodiments of the disclosure generally provide methods of forming a capacitor layer or a gate insulating layer with high dielectric constant as well as low film current leakage and desired film qualities for display applications. In one embodiment, a thin film transistor structure includes a dielectric layer formed on a substrate, wherein the dielectric layer is a zirconium containing material comprising aluminum, and gate, source and drain electrodes formed on the substrate, wherein the gate, source and drain electrodes formed above or below the dielectric layer.

Abstract: Embodiments described herein relate to a sub-pixel. The sub-pixel includes an anode, overhang structures, separation structures, an organic light emitting diode (OLED) material, and a cathode. The anode is defined by adjacent first pixel isolation structures (PIS) and adjacent second PIS. The overhang structures are disposed on the first PIS. The overhang structures include a second structure disposed over the first structure and an intermediate structure disposed between the second structure and the first structure. A bottom surface of the second structure extends laterally past an upper surface of the first structure. The first structure is disposed over the first PIS. Separation structures are disposed over the second PIS. The OLED material is disposed over the anode and an upper surface of the separation structures. The cathode disposed over the OLED material and an upper surface of the separation structures.

Abstract: A method, computer program product, and computer system for public speaking guidance is provided. A processor retrieves speaker data regarding a speech made by a user. A processor separates the speaker data into one or more speaker modalities. A processor extracts one or more speaker features from the speaker data for the one or more speaker modalities. A processor generates a performance classification based on the one or more speaker features. A processor sends to the user guidance regarding the speech based on the performance classification.

Abstract: Embodiments described herein relate to a sub-pixel. The sub-pixel includes an anode, overhang structures, separation structures, an organic light emitting diode (OLED) material, and a cathode. The anode is defined by adjacent first pixel isolation structures (PIS) and adjacent second PIS. The overhang structures are disposed on the first PIS. The overhang structures include a second structure disposed over the first structure and an intermediate structure disposed between the second structure and the first structure. A bottom surface of the second structure extends laterally past an upper surface of the first structure. The first structure is disposed over the first PIS. Separation structures are disposed over the second PIS. The OLED material is disposed over the anode and an upper surface of the separation structures. The cathode disposed over the OLED material and an upper surface of the separation structures.

Abstract: Embodiments described herein relate to a sub-pixel. The sub-pixel includes an anode, overhang structures, separation structures, an organic light emitting diode (OLED) material, and a cathode. The anode is defined by adjacent first pixel isolation structures (PIS) and adjacent second PIS. The overhang structures are disposed on the first PIS. The overhang structures include a second structure disposed over the first structure and an intermediate structure disposed between the second structure and the first structure. A bottom surface of the second structure extends laterally past an upper surface of the first structure. The first structure is disposed over the first PIS. Separation structures are disposed over the second PIS. The OLED material is disposed over the anode and an upper surface of the separation structures. The cathode disposed over the OLED material and an upper surface of the separation structures.

Abstract: The present disclosure relates to a technology of preparing an anion exchange composite membrane including: a porous polymer support; and a polyfluorene-based anion exchange membrane or a polyfluorene-based anion exchange membrane having a cross-linked structure formed on the support, and applying the same to alkaline fuel cells, water electrolysis, carbon dioxide reduction, metal-air batteries, etc. The polyfluorene-based anion exchange composite membrane including a porous polymer support according to the present disclosure has remarkably improved mechanical properties, dimensional stability, durability, long-term stability, etc.

Abstract: A computer-implemented method according to one embodiment includes running an initial network on a plurality of images to detect actors pictured therein and body joints of the detected actors. The method further includes running fully-connected networks in parallel, one fully-connected network for each of the detected actors, to reconstruct complete three-dimensional poses of the actors. Sequential model fitting is performed on the plurality of images. The sequential model fitting is based on results of running the initial network and the fully-connected networks. The method further includes determining, based on the sequential model fitting, a locational position for a camera in which the camera has a view of a possible point of collision of two or more of the actors. The camera is instructed to be positioned in the locational position.

Abstract: A computer that determines at least an anatomic feature of a left atrial appendage (LAA) is described. During operation, the computer generates a 3D image associated with an individual's heart. This 3D image may present a view along a perpendicular direction to an opening of the LAA. Then, the computer may receive information specifying a set of reference locations. For example, the set of reference locations may include: a location on a circumflex artery, a location between a superior portion of the LAA and a left pulmonary vein, and/or a location on a superior wall of the LAA and distal to trabeculae carneae. Next, the computer automatically determines, based, at least in part, on the set of reference locations, at least the anatomical feature of the LAA, which is associated with the opening of the LAA and a size of a device used in an LAA closure (LAAC) procedure.

Abstract: A biological desulfurization processing system is provided. The biological desulfurization processing system includes a desulfurization reaction tank and a culture tank of desulfurization bacteria. The culture tank of desulfurization bacteria is used for cultivating desulfurization bacteria and is connected to the desulfurization reaction tank. The desulfurization reaction tank includes a desulfurization reaction zone. The desulfurization reaction zone includes at least one desulfurization layer and at least one supporting layer, and the desulfurization layer and the supporting layer are stacked in a staggered manner. A biological desulfurization processing method is also provided.

Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds as exemplified as follows, The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.

Abstract: Provided is a forming method of a metal layer suitable for a 3D printing process. The method includes the steps of (1) providing first metal particles on a substrate to form a first layer; (2) performing a first pre-heat treatment on the first layer; (3) applying an oxide-removing agent on selected first metal particles in the first layer to remove metal oxides; (4) providing second metal particles on the first layer to form a second layer; (5) performing a second pre-heat treatment on the second layer; (6) applying the oxide-removing agent on selected second metal particles in the second layer to remove metal oxides; repeating (1) to (6) until a latent part is formed; performing a first heat treatment on the first and second metal particles of the latent part to form a near shape; and performing a second heat treatment on the near shape to form a sintered body.

Abstract: A composite material is provided, which includes powder of a polymer uniformly distributed in a blend of the polymer and a compound. The polymer and the compound have similar molecular structure. The compound has a first initially melting temperature and a first completely melting temperature. The polymer has a second initially melting temperature and a second completely melting temperature. The first completely melting temperature is lower than the second initially melting temperature.

Abstract: A computer that determines at least an anatomic feature associated with an aortic valve is described. During operation, the computer generates a 3D image associated with an individual's heart. This 3D image may present a view along a perpendicular direction to a 2D plane in which bases of a noncoronary cusp, a right coronary cusp and a left coronary cusp reside. Then, the computer may receive information specifying a set of reference locations that are associated with an aortic-root structure. Next, the computer automatically determines, based, at least in part, on the set of reference locations, at least the anatomical feature, which is associated with an aortic valve of the individual and a size of an aortic-valve device used in a transcatheter aortic-valve replacement (TAVR) procedure.

Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds as exemplified as follows, The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.

Abstract: Provided is a forming method of a metal layer suitable for a 3D printing process. The method includes the steps of providing a plurality of metal particles on a substrate; applying an oxide-removing agent to the metal particles to remove metal oxides on the metal particles; at a first temperature, performing a first heat treatment on the metal particles for which the metal oxides are removed to form a near shape; and at a second temperature, performing a second heat treatment on the near shape to form a sintered body. The first temperature is lower than the second temperature.

Abstract: The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of lysine specific demethylase-1. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.

Abstract: A dispersion of IR absorption particles is provided, which includes 100 parts by weight of IR absorption particles, 5 to 30 parts by weight of diblock copolymer, and 200 to 910 parts by weight of water, wherein the diblock copolymer includes (a) first block of and (b) second block of wherein (a) first block is chemically bonded to (b) second block; R1 is H or CH3; R2 is H or CH3; R3 is R4 is C1-10 alkyl group; M? is Na+, NH4+, or NH(C2H4OH)3+; m=10-20; n=2-20; and x=0-4.