Abstract: The present disclosure relates a focused ultrasound operation apparatus suitable for providing a controllable rotation angle. The focused ultrasound operation apparatus includes: a handpiece provided for manipulation by an operator; a cartridge of a body-insertion type which is detachably coupled to the handpiece and includes an ultrasound emitting portion. In particular, the handpiece includes: a rotation module portion provided for the operator to rotate the cartridge coupled to the handpiece; a case arranged outside the rotation module portion; and a cartridge rotation angle adjustor to adjust a rotation angle of the cartridge with respect to a rotation motion around a center axis in a body-insertion direction of the cartridge, interacting with a rotation of the rotation module portion.