Abstract: A medication dosage regulation apparatus is provided for guiding the safe and reliable administration of medication in accordance with the prescribed procedure. The apparatus generally comprises a patient's medication holder and a removable cover substantially enveloping that medication holder. The medication holder includes a plurality of compartments for respectively storing a plurality of medication doses to be administered in compliance with the prescribed procedure. The medication holder for the corresponding time and auxiliary indicia for guiding the user. The cover is marked with identification indicia pertaining to the intended recipient of the medication doses. In certain embodiments, the apparatus also comprises at least one overlay removably attached to the medication holder for bearing at least a portion of the time and auxiliary indicia.