Patents by Inventor Young-Deug Kim
Young-Deug Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9751941Abstract: A multi-transmembrane protein antigen includes a polypeptide corresponding to an extracellular loop of the multi-transmembrane protein, the N-terminal and C-terminal of the polypeptide being fixed on a solid substrate or the N-terminal and C-terminal being attached to both ends of a linker to form a cyclic structure, an antibody specifically binding to the antigen or an antigen-binding fragment thereof, and a method for screening an antibody specifically binding to the antigen. The present invention may be usefully employed for effective production of antibodies for multi-transmembrane proteins that play important roles in disease-related phenomena such as cell signaling.Type: GrantFiled: March 14, 2013Date of Patent: September 5, 2017Assignee: Abion Inc.Inventors: Young Kee Shin, Young-Deug Kim, Jun Young Choi, Myung Seok Lee
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Patent number: 9719093Abstract: The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer associated with HPV, and even more specifically, cervical cancer. The nucleotide sequence of the present invention, the sequence in which the base thereof is modified, and a specific combination thereof can be useful in a composition for effectively treating diseases associated with HPV infection by greatly inhibiting the expression of the E6/E7 gene of HPV type 16 or 18.Type: GrantFiled: August 1, 2013Date of Patent: August 1, 2017Assignee: Abion Inc.Inventors: Young Kee Shin, Young-Deug Kim, Hun Soon Jung, Deuk Ae Kim
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Publication number: 20170209588Abstract: The present invention provides a PEGylated IFN-? variant and a composition for preventing or treating hyperproliferative diseases, inflammatory diseases, autoimmune diseases or viral infectious diseases, the composition comprising the PEGylated IFN-? variant as an effective ingredient. The PEGylated IFN-? variant of the present invention has an excellent anti-viral efficacy, immune regulatory function and anti-cell growth efficacy by virtue of better pharmacokinetic properties compared to native IFN-? and non-PEGylated IFN-? variants, and therefore can be used usefully against various diseases. The present invention provides good patient convenience in terms of administration due to exhibition of an excellent pharmacological activity effect upon administration and a significant increase of half-life in blood over existing interferon formulations.Type: ApplicationFiled: July 24, 2015Publication date: July 27, 2017Inventors: Young-Kee SHIN, Young-Deug KIM, Kyoung SONG, Dong Hee NA, Seong Hoon JEONG, Dae Duk KIM, In Soo YOON, Hee Jung LEE, Sae Hyung LEE
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Publication number: 20170198291Abstract: The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer associated with HPV, and even more specifically, cervical cancer. The nucleotide sequence of the present invention, the sequence in which the base thereof is modified, and a specific combination thereof can be useful in a composition for effectively treating diseases associated with HPV infection by greatly inhibiting the expression of the E6/E7 gene of HPV type 16 or 18.Type: ApplicationFiled: February 23, 2017Publication date: July 13, 2017Inventors: Young Kee SHIN, Young Deug KIM, Hun Soon JUNG, Deuk Ae KIM
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Publication number: 20170159126Abstract: The present invention relates to a method for selecting a gene intended to predict the prognosis for a cancer, to the selected gene for predicting the prognosis of cancer and to a kit for predicting and a method for predicting metastasis in breast-cancer patients by using the same. In the present invention, a straight forward method is used to achieve high-reliability prediction of the patient's prognosis by analysing for the genetic characteristics of early stage breast cancer, and thus the present invention can be used to advantage in prognosis diagnosis which can reduce unnecessary anticancer therapy.Type: ApplicationFiled: October 4, 2016Publication date: June 8, 2017Inventors: YOUNG KEE SHIN, YOUNG-DEUG KIM, EN SEL OH, SI EUN KIM
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Publication number: 20160102359Abstract: A gene for predicting or diagnosing the prognosis of early-stage breast cancer and to a use thereof is disclosed, and more specifically a genetic marker for predicting or diagnosing the prognosis of breast cancer, including TRBC1 (T cell receptor beta constant 1), BTN3A2 (butyrophilin, subfamily 3 member A2) or HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1) for providing information necessary for predicting or diagnosing the prognosis of a breast cancer patient. The genetic marker allows the prediction or diagnosis of the prognosis of a breast cancer patient, and can therefore advantageously be used for the purpose of providing a direction as to the future course of breast cancer treatment, including a decision on whether anticancer therapy is necessary.Type: ApplicationFiled: October 19, 2015Publication date: April 14, 2016Inventors: Young Kee SHIN, Young-Deug Kim, En Sel Oh, Jun Young Choi, Sang Rea Cho
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Publication number: 20150299711Abstract: The present invention relates to a composition for preventing or treating diseases associated with human papillomavirus (HPV), and more specifically, cancer associated with HPV, and even more specifically, cervical cancer. The nucleotide sequence of the present invention, the sequence in which the base thereof is modified, and a specific combination thereof can be useful in a composition for effectively treating diseases associated with HPV infection by greatly inhibiting the expression of the E6/E7 gene of HPV type 16 or 18.Type: ApplicationFiled: August 1, 2013Publication date: October 22, 2015Inventors: Young Kee SHIN, Young-Deug KIM, Hun Soon JUNG, Deuk Ae KIM
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Patent number: 8969296Abstract: The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-?1 (transforming growth factor-?1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF-?1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF-?1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics.Type: GrantFiled: September 12, 2007Date of Patent: March 3, 2015Assignee: Caregen Co., LtdInventors: Yong-Ji Chung, Young Deug Kim, Eun Mi Kim, Jun Young Choi, Jin Seuk Kim, Sang Su Song, Kyoung Mi Cho
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Publication number: 20140274755Abstract: A multi-transmembrane protein antigen includes a polypeptide corresponding to an extracellular loop of the multi-transmembrane protein, the N-terminal and C-terminal of the polypeptide being fixed on a solid substrate or the N-terminal and C-terminal being attached to both ends of a linker to form a cyclic structure, an antibody specifically binding to the antigen or an antigen-binding fragment thereof, and a method for screening an antibody specifically binding to the antigen. The present invention may be usefully employed for effective production of antibodies for multi-transmembrane proteins that play important roles in disease-related phenomena such as cell signaling.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: REFERENCE BIOLABS INC.Inventors: Young Kee SHIN, Young-Deug KIM, Jun Young CHOI, Myung Seok LEE
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Patent number: 8729028Abstract: Disclosed are a noggin-derived peptide and a composition containing the same for promoting hair growth, improving skin conditions, providing anti-inflammatory function, or preventing or treating bone diseases. The disclosed noggin-derived peptide performs a function identical or similar to that of natural human noggin and is superior in stability and skin permeability as compared thereto. The composition containing the peptide of the present disclosure as an active ingredient exhibits remarkably superior effects in treating, preventing or improving growth factor-related symptoms, e.g. hair loss, skin conditions or cut, or treating, preventing or improving growth factor overexpression-related symptoms. Therefore, the superior activity and stability of the peptide of the present disclosure are greatly advantageous in application to medicine, quasi-drugs and cosmetics.Type: GrantFiled: November 24, 2009Date of Patent: May 20, 2014Assignee: Caregen Co., Ltd.Inventors: Young Ji Chung, Young Deug Kim, Eun Mi Kim, Sang Su Song, Il Hong, Kyoung Mi Cho, Su Mi Kim, Sang Min Han
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Patent number: 8691195Abstract: The present invention relates to a transforming growth factor-beta (TGF-?)-mimicking peptide containing a particular amino acid sequence and a composition for preventing or treating TGF-?-effective disorders or conditions using the same. The peptide of the present invention may be much higher stability than natural-occurring TGF-? and improve drawbacks caused by high molecular weight of natural-occurring TGF-?. The peptide of this invention can be advantageously applied to treatment or improvement of TGF-?-effective disorders or conditions and have excellent efficacies on skin whitening and wrinkle improvement.Type: GrantFiled: April 14, 2009Date of Patent: April 8, 2014Assignee: Caregen Co., Ltd.Inventors: Young Ji Chung, Young Deug Kim, Eun Mi Kim, Jeong Jin Choi, Jun Young Choi
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Publication number: 20130344482Abstract: The present invention relates to a method for selecting a gene intended to predict the prognosis for a cancer, to the selected gene for predicting the prognosis of cancer and to a kit for predicting and a method for predicting metastasis in breast-cancer patients by using the same. In the present invention, a straight forward method is used to achieve high-reliability prediction of the patient's prognosis by analysing for the genetic characteristics of early stage breast cancer, and thus the present invention can be used to advantage in prognosis diagnosis which can reduce unnecessary anticancer therapy.Type: ApplicationFiled: July 4, 2013Publication date: December 26, 2013Applicant: Gencurix IncInventors: Young Kee Shin, Yoon La Choi, Young-Deug Kim, Eu Sel Oh, Si Eun Kim
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Patent number: 8501689Abstract: The present invention relates to a growth factor-mimicking peptide having an activity of the growth factor, and a composition and a method for improving skin conditions or for treating a wound using the same. The growth factor-mimicking peptides of this invention have identical functions or actions to natural-occurring human growth factor, and much better stability and skin penetration potency than natural-occurring growth factor. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding growth factor activities. In addition, excellent activity and stability of the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.Type: GrantFiled: March 6, 2009Date of Patent: August 6, 2013Assignee: Caragen Co., Ltd.Inventors: Yong-Ji Chung, Young Deug Kim, Eun Mi Kim, Jun Young Choi
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Patent number: 8263095Abstract: The present invention relates to a peptide having the activity of insulin like growth factor-1 (IGF-1) and derived from IGF-1, a composition for improving skin conditions or treating a periodontal disease comprising the peptide. The IGF-1 mimicking peptides of this invention have identical functions or actions to natural-occurring IGF-1 and much better stability and skin permeation than natural-occurring IGF-1. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding IGF-1 activities. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.Type: GrantFiled: March 12, 2010Date of Patent: September 11, 2012Assignee: Caregen Co., Ltd.Inventors: Yong Ji Chung, Young Deug Kim, Eun Mi Kim
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Patent number: 8188049Abstract: The present invention relates to peptides comprising the amino acid sequence represented by the following formula 1 and having the activities of epidermal growth factor and their uses: Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp (1) The EGF-mimicking peptides of the present invention possess identical functions or activities to natural-occurring human EGF and are able to promote the generation of autocrine EGF in cells. In addition the peptides of the present invention are much higher stability and skin penetration potency than natural-occurring EGF. Therefore, the composition containing the peptide exhibits excellent treatment and prevention efficacies on diseases or conditions demanding EGF activities, and can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.Type: GrantFiled: October 8, 2007Date of Patent: May 29, 2012Assignee: Caregen Co., Ltd.Inventors: Yong-Ji Chung, Young Deug Kim, Eun Mi Kim, Jun Young Choi, Sang Su Song
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Publication number: 20120114577Abstract: The present invention relates to a transforming growth factor-beta (TGF-?)-mimicking peptide containing a particular amino acid sequence and a composition for preventing or treating TGF-?-effective disorders or conditions using the same. The peptide of the present invention may be much higher stability than natural-occurring TGF-? and improve drawbacks caused by high molecular weight of natural-occurring TGF-?. The peptide of this invention can be advantageously applied to treatment or improvement of TGF-?-effective disorders or conditions and have excellent efficacies on skin whitening and wrinkle improvement.Type: ApplicationFiled: April 14, 2009Publication date: May 10, 2012Applicant: CAREGEN CO., LTD.Inventors: Young Ji Chung, Young Deug Kim, Eun Mi Kim, Jeong Jin Choi, Jun Young Choi
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Patent number: 8106017Abstract: The present invention relates to a peptide comprising a specific amino acid sequence possessing human thymosin ?-4 (T?4) activities and its uses. The peptide of this invention has identical or similar functions or actions to human T?4 and its biological activity is almost identical to natural-occurring T?4. In addition, the peptide of this invention exhibits much higher stability and skin permeation than natural-occurring T?4. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in thymosin ?-4-effective disorders or conditions. In addition, the peptide of this invention can be advantageously applied to drugs, cosmetics, toothpaste and compositions for mouth cleaning and caring, most preferably, cosmetics. Specifically, the peptide of this invention is advantageously applied to cosmetics for promoting hair growth.Type: GrantFiled: October 24, 2006Date of Patent: January 31, 2012Assignee: Caregen Co., Ltd.Inventors: Yong Ji Chung, Young Deug Kim, Chung Ryul Kim
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Publication number: 20110312884Abstract: Disclosed are a noggin-derived peptide and a composition containing the same for promoting hair growth, improving skin conditions, providing anti-inflammatory function, or preventing or treating bone diseases. The disclosed noggin-derived peptide performs a function identical or similar to that of natural human noggin and is superior in stability and skin permeability as compared thereto. The composition containing the peptide of the present disclosure as an active ingredient exhibits remarkably superior effects in treating, preventing or improving growth factor-related symptoms, e.g. hair loss, skin conditions or cut, or treating, preventing or improving growth factor overexpression-related symptoms. Therefore, the superior activity and stability of the peptide of the present disclosure are greatly advantageous in application to medicine, quasi-drugs and cosmetics.Type: ApplicationFiled: November 24, 2009Publication date: December 22, 2011Applicant: Caregen Co., Ltd.Inventors: Young Ji Chung, Young Deug Kim, Eun Mi Kim, Sang Su Song, Il Hong, Kyoung Mi Cho, Su Mi Kim, Sang Min Han
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Publication number: 20110160131Abstract: The present invention relates to a growth factor-mimicking peptide having an activity of the growth factor, and a composition and a method for improving skin conditions or for treating a wound using the same. The growth factor-mimicking peptides of this invention have identical functions or actions to natural-occurring human growth factor, and much better stability and skin penetration potency than natural-occurring growth factor. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding growth factor activities. In addition, excellent activity and stability of the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.Type: ApplicationFiled: March 6, 2009Publication date: June 30, 2011Applicant: Caregen Co., Ltd.Inventors: Yong-Ji Chung, Young Deug Kim, Eun Mi Kim, Jun Young Choi
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Patent number: 7939495Abstract: Provided is a method for improving a skin condition or treating a periodontal disease, which includes administering to a subject a composition including a basic fibroblast growth factor-derived peptide as an active ingredient. The present method effectively improves skin conditions and treats periodontal diseases. In addition, the present peptides can be applied to pharmaceutical compositions, cosmetics, toothpaste and compositions for mouth cleaning and care.Type: GrantFiled: October 24, 2006Date of Patent: May 10, 2011Assignee: Caregen Co., LtdInventors: Yong Ji Chung, Young Deug Kim, Chung Ryul Kim