Abstract: The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.

Abstract: The present disclosure relates to an apparatus for accommodating copper foil. The apparatus includes an accommodation body in which an accommodation space for accommodating copper foil wound on a core is provided, a first support portion coupled to the accommodation body to support one side of the core, a second support portion coupled to the accommodation body to support the other side of the core, a first damper portion coupled to the first support portion to be disposed between the first support portion and the one side of the core, and a second damper portion coupled to the second support portion to be disposed between the second support portion and the other side of the core, wherein the first damper portion includes a first damper body coupled to the first support portion and a plurality of first damper protrusions protruding from the first damper body.

Abstract: The present disclosure relates to a new soybean variety containing epicatechin with high content and having antioxidant and antiaging activities, a method for producing the new soybean variety, a composition containing an extract of the new soybean variety as an active ingredient, a functional health food containing the new soybean variety, a method for producing epicatechin from the new soybean variety, and a method for producing a commodity plant product. The seed of the new soybean (Glycine max) variety according to an aspect of the present disclosure contains epicatechin with a high content of 2 wt % or more based on the total weight of an 80 wt % ethanol aqueous solution of seed extract, exhibits 2 times or higher antioxidant activity confirmed by DPPH radical-scavenging ability than the mother plant IT109098, and exhibits superior collagenase (matrix metalloproteinase-1, MMP-1) expression inhibition as compared to EGCG, which is known as an antiaging substance.

Abstract: The present disclosure provides a method and apparatus for biomolecular multiplexed imaging through the iterative unmixing of fluorophores. According to the first embodiments of the present disclosure, although signals of two fluorophores are detected in the first fluorescent detection spectral range, the signals of the two images obtained from two detection spectral ranges can be unmixed through the iterative minimization of mutual information. Furthermore, the present disclosure provides a multi-color unmixing method and apparatus through the iterative minimization of mutual information. In the second embodiments of the present disclosure, a plurality of images of a plurality of fluorophores marking different biomolecules, respectively, for example, N fluorophores are obtained. Images, each containing the signals of single fluorophore can be obatined from the obtained images while minimizing the mutual information shared by images of each of pairs each consisting of two of the obtained images.

Abstract: An embodiment of the present disclosure may provide a microlens array including: an optical substrate configured to define multiple cells; and multiple microlenses distributed on the optical substrate and having angle profiles or tilting profiles, wherein angle profiles of the multiple cells are defined based on the shapes of edges of the cells, and tilting profiles of the multiple cells are defined based on the tilts of the microlenses or the tilt of the optical substrate.

Abstract: Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer containing the same. The novel antibody binding to PD-1 or an antigen-binding fragment thereof can bind to PD-1 and inhibit the activity of PD-1, thus being useful for the development of immunotherapeutic agents for various diseases associated with PD-1.

Abstract: Provided are a composition including a compound of the following chemical formula as an active ingredient and a method of inhibiting a cortisone reductase by applying the same:

Abstract: Provided are a composition including coumestrol extracted from soybeans as an active ingredient, and a method of inhibiting cortisone reductase by applying it to skin of a subject.

Abstract: The present invention relates to a core-shell network structure formed using a biocompatible biopolymer and to a composition comprising same. Said structure can be used as an alternative to synthetic chemical materials, such as polyethylene glycol (PEG), to effectively disperse an insoluble effective substance within a composition, thus addressing safety issues, and formulations can be preserved stably for a long time through said network structure. Furthermore, said structure and the composition comprising same may provide useful benefits for the skin in terms of skin barrier enhancement, skin moisturization, skin regeneration, or the like.

Abstract: An embodiment may provide a method for synchronizing a field of view of a distance measuring device including: a light source including one or more light source elements; and a light diffusion device through which light emitted from the light source passes, wherein the light diffusion device is divided into one or more regions, each of the light source elements of the light source is disposed with an independent region, and the intensity of light transferred from the light source elements is adjustable. The method may include: identifying a field of view (FOV) of a red, green, and blue (RGB) camera; and adjusting, based on a predetermined reference, the field of view of the distance measuring device such that the field of view of the distance measuring device corresponds to the field of view of the RGB camera.

Abstract: Provided is a composition for inhibiting cortisone reductase, including a compound represented by a specific chemical formula as an active ingredient.

Abstract: The present invention relates to a transmission of an agricultural work vehicle, the transmission comprising: a pre-shift part for performing speed shifting on driving transmitted from an engine of an agricultural work vehicle; a clutch part connected to the pre-shift part so as to selectively output driving transmitted from the pre-shift part; an adjusting part connected to the clutch part so as to perform speed shifting on driving transmitted from the clutch part; and a subsequent shift part connected to the adjusting part so as to perform speed shifting on driving transmitted from the adjusting part.

Abstract: Provided are a composition including a compound represented by a specific chemical formula as an active ingredient and a method of inhibiting a cortisone reductase by applying the same to skin of a subject.

Abstract: A golf practicing apparatus for providing a feedback with regard to a swing speed and form includes a hand portion, a strip portion, and a weight portion. The weight portion provides a signal when a player makes a swing with the apparatus and the signal indicates how the swing is made.

Abstract: A beam projector module including a light source configured to output light, a substrate configured to support the light source, an optical device configured to decrease the intensity of the light output to a predetermined space, an optical substrate, in which the optical device is disposed, and configured to transmit the light, and a frame configured to space the optical device apart from the light source by a predetermined distance, and including a support part configured to support the optical substrate, wherein the optical substrate is slidingly inserted through a first slot formed to pass through a first side surface of the frame, and is mounted on the frame such that a portion of an upper surface or a lower surface of the optical substrate contacts the support part.

Abstract: A fan motor for a vacuum cleaner includes a motor mount defining a cooling flow path inlet, an impeller, an impeller cover defining an air inlet, an air discharge opening defined at the motor mount and configured to discharge air to an outer space of the motor mount, and a cooling flow path outlet defined vertically above the motor mount. The cooling flow path inlet is configured to introduce air from the outer space of the motor mount into an inner space of the motor mount to cool the motor part, and the cooling flow path outlet is configured to discharge air from the inner space of the motor mount toward a space that is defined between the impeller and the air discharge opening based on the space between the impeller and the air discharge opening having a lower pressure than the inner space of the motor mount.

Abstract: An embodiment provides a beam projector module including: a light source configured to output light; a substrate configured to support the light source; an optical device configured to reduce the light in terms of intensity output to a predetermined space; a frame configured to separate the optical device from the light source by a predetermined distance; an optical substrate configured to attach the optical device thereto and to define a sealed space with the substrate and the frame, the sealed space having internal pressure lower than pressure outside the sealed space; a sensor configured to measure a state of the sealed space; and a processor configured to change an operation mode of the light source depending on a measured value of the sensor.

Abstract: One embodiment may provide a light source module including: a light source including at least one vertical cavity surface-emitting laser, which is configured to transfer light through N (N being a natural number equal to or greater than 1) apertures; at least one collimator lens through which light emitted from the light source passes; and a driving device configured to make the collimator lens move, wherein the at least one vertical cavity surface-emitting laser comprises divided regions, and an intensity of a beam is controlled according to a predetermined far-distance mode or near-distance mode

Abstract: One embodiment may provide a light source module including: a light source part including at least one vertical cavity surface-emitting laser, which is configured to transfer light through N (N being a natural number equal to or greater than 1) apertures; at least one collimator lens through which light emitted from the light source part passes; and a driving device configured to make the collimator lens move, wherein the at least one vertical cavity surface-emitting laser comprises divided regions, and an intensity of a beam is controlled according to a predetermined far-distance mode or near-distance mode

Abstract: An embodiment provides a beam projector module that includes: a light source configured to output light; a substrate configured to support the light source; an optical device configured to reduce the light in terms of intensity output to a predetermined space; a frame configured to space the optical device apart from the light source by a predetermined distance, the frame forming a closed space with the substrate and the optical device; a temperature sensor configured to measure a temperature of the frame; and a processor configured to control an output of the light source. The processor is configured to operate the light source in an eye-safety mode when a temperature drop rate of the frame exceeds a reference value.