Abstract: The apparatus includes a support unit to support the substrate in a treatment space of a process chamber, a first fluid supply unit to supply a supercritical fluid having an organic solvent dissolved in the supercritical fluid, to the treatment space, a second fluid supply unit to supply the supercritical fluid having no organic solvent dissolved in the supercritical fluid, to the treatment space, an exhaust unit to exhaust the treatment space, a controller to control the first fluid supply unit, the second fluid supply unit, and the exhaust unit. The controller controls the first and second fluid supply units such that the supercritical fluid having no organic solvent dissolved in the supercritical fluid is supplied to the treatment space through the second fluid supply unit, after the supercritical fluid mixed with the organic solvent is supplied to the treatment space through the first fluid supply unit.

Abstract: The present invention relates to a photocuring generation-gas collecting device, which collects gas generated from a sample when the sample is subjected to photocuring using various light wavelengths including ultraviolet rays.

Abstract: An interface and a sample analysis method using the same are disclosed herein. In some embodiments, an interface is between a liquid chromatography (LC), an ionization device, and a mass spectrometer (MS), wherein a sample containing a target eluted from the liquid chromatography is ionized by the ionization device and the sample is introduced into the mass spectrometer, wherein the interface includes a droplet sprayer, an evaporator having a heatable block, and an introduction tube, wherein the heatable block has one or more openings, the droplet sprayer for coverting the sample into sample droplets and for spraying the sample droplets, the evaporator for evaporating a solvent in the sample droplets to generate a gaseous target by passing the droplets through the one or more openings, the introduction tube for receiving the gaseous target and for introducing an ionized gaseous target into the mass spectrometer.

Abstract: The present disclosure relates to a method for analysis of a deuterium substitution rate of a deuterium-substituted sample according to substitution positions using information of a 1H-NMR spectrum of the deuterium-substituted sample.

Abstract: The present disclosure relates to a method for analysis of an average deuterium substitution rate of a deuterium-substituted sample using information of a 1H-NMR spectrum of the deuterium-substituted sample.

Abstract: An on-line system that performs concentration and solvent exchange in order to improve a detection level of analytes by a liquid chromatograph (LC) is provided. The on-line system comprises: a first pump and a second pump for supplying a solvent; a liquid chromatograph (LC) including a separation column (SC) connected to the first pump; a trapping column (TC) for collecting the analytes separated from the separation column; a concentration column (CC) for concentrating the analytes collected in the trapping column (TC); a detector; and first to third switching valves that communicate fluid with at least one of the first or second pumps. An analysis method using the same is also provided.

Abstract: The present disclosure relates to a method for predicting photostability of an organic material within a short time using LA-DART-MS, the method including the steps of: irradiating a specimen containing an organic material with a laser beam; obtaining a mass spectrum of components desorbed and ionized from the specimen; and calculating a degradation yield of the mathematical expression 1 according to the present disclosure from the mass spectrum. The method for predicting photostability of an organic material according to the present disclosure as described above can predict photostability within seconds to minutes, which is a remarkably short time, as compared with a conventional method for measuring photostability of an organic material.

Abstract: The present invention relates to an interface unit which can be used in a laser ablation-direct analysis in real time-mass spectrometry (LA-DART-MS) system, and more particularly, provides an interface unit which can be disposed between a DART unit and an MS unit to improve detection sensitivity of a sample laser-ablated by a laser beam.

Abstract: A method for relative quantitative analysis of a polymer using MALDI mass spectrometry, the method comprising the steps of preparing a plurality of polymer specimens having a thickness variation of 30% or less by electrospraying a solution including a polymer sample, a monomeric internal standard material, and a matrix through a mask for each different concentration of the polymer sample; obtaining MALDI mass spectra by irradiating laser beams to each of the plurality of polymer specimens, and calculating a signal intensity ratio of the polymer sample to the small molecule internal standard from peak results of the spectra; and depicting the calculated signal intensity ratio according to the concentration of the polymer sample to prepare a quantitative calibration curve, and the method capable of providing MALDI mass spectra with reduced overlapping peaks and thereby providing the relative quantitative analysis of a polymer with improved accuracy.

Abstract: A method for analyzing the structure of an insoluble pigment compound is disclosed. In some embodiments, a method comprise determining a molecular weight of the pigment compound, the insoluble pigment compound by ultrasonic treatment in a solvent to form partial structural compounds, analyzing the elemental composition and the structure of partial structural compounds by liquid chromatography/mass spectrometry and nuclear magnetic resonance, respectively and determining the structure of the insoluble pigment compound from the analysis of the partial structural compounds and the molecular weight of the insoluble pigment compound.

Abstract: The present invention relates to a composition for preventing or treating obesity containing an ethanolic extract of Ramulus mori as an active ingredient. As the present invention contains an ethanolic extract of Ramulus mori, extracted from natural substance Ramulus mori, as an active ingredient, the present invention may prevent or treat obesity by inhibiting lipid accumulation in adipocytes without any side effects to a human body and inhibiting preadipocytes from being differentiated into adipocytes.

Abstract: The present invention relates to a method for producing test pieces in which the thickness of the samples of homogeneous water-insoluble material is uniform, and to a method for quantitative analysis of water-insoluble material by analyzing such test pieces using MALDI mass spectrometry. Specifically, the test pieces can be produced by: adding a volatile solvent to a mixture of water-insoluble material and matrix; placing, in a pellet cup made of water-soluble material, and pressing, with even pressure, the sample obtained by mixing the mixture of water-insoluble material and matrix until the solvent has evaporated; and melting the pellet cup with water.

Abstract: A pretreatment method for analyzing dioxin compounds and an analytical method using the same, in which a column packed with polymer beads that are capable of selectively adsorbing dioxin compounds is used in a purification step during pretreatment, thereby remarkably reducing a time required for pretreatment and improving a recovery rate of an internal standard for purification, are provided.

Abstract: The present invention provides a method for relative quantitative analysis of a polymer using MALDI mass spectrometry, the method comprising the steps of: (S1) electro-spraying a solution containing a polymer sample and a matrix through a mask to prepare a plurality of polymer specimens with a thickness variation of 30% or less according to the concentration of the polymer sample; (S2) irradiating the respective plurality of polymer specimens with laser to obtain MALDI mass spectra; and (S3) creating a quantitative calibration curve from peak results of the MALDI mass spectra by using a signal of the polymer sample.

Abstract: The present disclosure relates to a method for analysis of a deuterium substitution rate of a deuterium-substituted sample according to substitution positions using information of a 1H-NMR spectrum of the deuterium-substituted sample.

Abstract: An on-line system that performs concentration and solvent exchange in order to improve a detection level of analytes by a liquid chromatography (LC) is provided. The on-line system comprises: a first pump and a second pump for supplying a solvent; a liquid chromatography (LC) including a separation column (SC) connected to the first pump; a trapping column (TC) for collecting the analytes separated from the separation column; a concentration column (CC) for concentrating the analytes collected in the trapping column (TC); a detector; and first to third switching valves that communicate fluid with at least one of the first or second pumps. An analysis method using the same is also provided.

Abstract: The present disclosure relates to a method for analysis of an average deuterium substitution rate of a deuterium-substituted sample using information of a 1H-NMR spectrum of the deuterium-substituted sample.

Abstract: A method for relative quantitative analysis of a polymer using MALDI mass spectrometry, the method comprising the steps of preparing a plurality of polymer specimens having a thickness variation of 30% or less by electrospraying a solution including a polymer sample, a monomeric internal standard material, and a matrix through a mask for each different concentration of the polymer sample; obtaining MALDI mass spectra by irradiating laser beams to each of the plurality of polymer specimens, and calculating a signal intensity ratio of the polymer sample to the small molecule internal standard from peak results of the spectra; and depicting the calculated signal intensity ratio according to the concentration of the polymer sample to prepare a quantitative calibration curve, and the method capable of providing MALDI mass spectra with reduced overlapping peaks and thereby providing the relative quantitative analysis of a polymer with improved accuracy.

Abstract: The present disclosure relates to a method of manufacturing a specimen of a poorly water-soluble material having a uniform thickness by using a sample plate comprising a substrate and a plurality of protrusions located on one surface of the substrate, the protrusion having a flat surface for receiving a force when pressed from the top, and a method for quantitative analysis of a poorly water-soluble material through MALDI mass spectrometry for the specimen.

Abstract: The present invention relates to an interface unit which can be used in a laser ablation-direct analysis in real time-mass spectrometry (LA-DART-MS) system, and more particularly, provides an interface unit which can be disposed between a DART unit and an MS unit to improve detection sensitivity of a sample laser-ablated by a laser beam.