Abstract: The present invention relates to a composition, a kit, a nucleic acid chip and a method which allow the diagnosis of liver cancer by detecting methylation levels of CpG sites of any one or more genes selected from the group consisting of FAM110A, FAR1, VIM, LDHB, LIPE, INAFM1, ATL1, CELF6, MTHFD2, PAK1, NXPE3, SLC25A36 and VANGL2. The present invention enables accurate and rapid diagnosis of liver cancer, and also enables early diagnosis.

Abstract: Systems and methods are disclosed for processing information related to appointment systems as well as associated terminal operating systems and other related systems. According to one illustrative implementation, an exemplary method for processing information involving appointment systems herein may include receiving/handling/processing data in a TOS format associated with a TOS type, converting the data into a TOS agnostic format, and performing processing using the TOS agnostic data. In another exemplary implementation, there is provided computer-implemented methods for processing information for appointment systems in conjunction with associated systems and operations. Systems and computer-implemented methods herein may include or involve processing information related to an appointment system and interrelationships with associated terminal operating systems, gate systems, and/or various TOS-agnostic features and functionality.

Abstract: The present invention relates to a novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof, a production method therefor and a pharmaceutical composition for preventing and treating central nervous system disorders which contains the same as an active component. The novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof according to the present invention can beneficially be used to prevent and treat central nervous system disorders since it exhibits an equivalent biological and pharmacological activity to venlafaxine and salts thereof which are known in the field, it has very little toxicity, and, in particular, it is outstandingly soluble in water as compared with prior-art venlafaxine derivatives.

Abstract: The present invention relates to a method for inducing the differentiation of neural progenitors, neurons, and dopaminergic neurons from human embryonic stem cells with high efficiency, in which neural selection can be performed by the selected media and physical methods. The invention has advantages such as higher efficiency, the effect of lowering cost and time, and maintenance of neural progenitors for a longer period of time, as compared to the known methods for inducing the differentiation into neural progenitors, neurons, and dopaminergic neurons. Accordingly, the method can stably generate cells used for treating Parkinson's disease or other nervous system diseases.