Patents by Inventor Young-Il Yang
Young-Il Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250051914Abstract: A silicon precursor compound according to Formula I as described herein is used to form a silicon-containing thin film having excellent quality. A preparation method therefor, and a silicon-containing thin film preparation method using the silicon precursor compound are also described.Type: ApplicationFiled: October 25, 2024Publication date: February 13, 2025Applicant: MERCK PATENT GmbHInventors: Byeong-IL Yang, Hee-Yeon Jeong, Yeong-Ju Seong, Seong-Hak Cheon, Joo-Yong Kim, Young-Hun Byun
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Publication number: 20240277902Abstract: The present invention relates to a method for manufacturing a peripheral nerve-mimicking microtissue and to uses thereof, and relates to a method for manufacturing a peripheral nerve-mimicking microtissue having a diameter of 100±20 ?m composed of about 100 to 500 cells, comprising isolating an culturing peripheral nerve-derived stem cells (PNSCs), and forming a cell-to-cell and cell-to-extracellular matrix binding through suspension culture of the isolated and cultured PNSCs, wherein the microtissue produced by culturing in a suspended culture environment has structural properties in which about 100 to 500 cells are assembled through cell-to-cell binding by ?-catenin, the extracellular matrix (ECM) produced and secreted by the PNSCs between cells accumulates, and binding is performed by ?1-integrin between the accumulated ECM and cells, and this is similar to the peripheral nerve composition and constituent cells that are regenerated after injury.Type: ApplicationFiled: June 7, 2022Publication date: August 22, 2024Applicant: INNOSTEM BIOInventors: Young-Il YANG, Won Jin LEE, Chung Eun YEUM
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Patent number: 11692171Abstract: The present invention relates to a preparation method of a spheroid using human-derived cardiac stem cells and a therapeutic use for ischemic heart disease using the myocardial regeneration effect thereof. The spheroid using the cardiac stem cells provided in the present invention has excellent myocardial differentiation ability and regenerative therapeutic ability as compared to existing cardiac stem cells, and thus may be used for the treatment of ischemic heart disease such as myocardial infarction.Type: GrantFiled: June 29, 2018Date of Patent: July 4, 2023Assignees: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, HIERABIO INC.Inventors: Seung Jin Lee, Young-il Yang
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Patent number: 11666604Abstract: Disclosed are a multilayered cell sheet of cardiac stem cells (CSCs) and a method of manufacturing the same. In particular, the present disclosure provides a method of manufacturing a multilayered cell sheet according to a single step culture procedure by using, as a three-dimensional matrix, a biodegradable natural polymer hydrogel and embedding CSCs in the hydrogel. The multilayered cell sheet of the present disclosure does not require any special device for the manufacturing, is manageable with good physicomechanical property, increases a cell engraftment rate after transplantation based on sufficient accumulation of various growth and protective factors and extracellular matrix between cells, and is also self-assembled by the cell-mediated hydrogel compaction, making nutrients transfer easy. Therefore, the multilayered cell sheet of the CSCs is expected to be usefully applicable as a therapeutic agent for myocardium regeneration.Type: GrantFiled: December 18, 2017Date of Patent: June 6, 2023Assignees: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Young-Il Yang, Ki-Dong Park, Won-Jin Lee, Min-Young Choi, Kyung-Min Park, Yun-Ki Lee
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Patent number: 11666684Abstract: A method of manufacturing a multilayered cell sheet of neural crest stem cells (NCSCs), includes: (1) isolating and culturing NCSCs from peripheral nerves; (2) embedding the cultured NCSCs in a hydrogel; (3) culturing the hydrogel comprising the NCSCs embedded therein under stressed culture conditions in which a physical support is applied; and (4) culturing the resulting hydrogel of step (3) under non-stressed culture conditions in which a physical support is removed.Type: GrantFiled: December 18, 2017Date of Patent: June 6, 2023Assignee: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Young-Il Yang, Won-Jin Lee, Jong-Tae Kim
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Publication number: 20220112465Abstract: Provided are a method of preparing synovium-derived mesenchymal stem cells using a synovial tissue and a hydrogel, synovium-derived mesenchymal stem cells prepared by the method, a pharmaceutical composition for treating bone or cartilage damage, the pharmaceutical composition including the synovium-derived mesenchymal stem cells, and a composition and kit for culturing mesenchymal stem cells, the composition and kit including a synovial tissue and a hydrogel. When the preparation method of the present invention is used, stem cells may be effectively extracted and obtained from synovium, and the obtained synovium-derived mesenchymal stem cells may effectively treat bone or cartilage damage, and therefore, it will be able to greatly contribute to the development of a method of treating bone or cartilage damage.Type: ApplicationFiled: September 27, 2019Publication date: April 14, 2022Inventors: Seung Jin Lee, Heejung Kim, Young-Il Yang
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Publication number: 20210308335Abstract: The present invention relates to a fibrous 3-dimensional porous scaffold obtained by electro-spinning for tissue regeneration and a method for preparing the same.Type: ApplicationFiled: October 7, 2013Publication date: October 7, 2021Applicant: EWHA UNIVERSITY -INDUSTRY COLLABORATION FOUNDATIONInventors: Seung Jin Lee, Sol Han, In Kyong Shim, Young Il Yang, Yang Soo Jang, Mi Ra Jung, Hye Jin Chung
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Publication number: 20210196761Abstract: Disclosed are a multilayered cell sheet of cardiac stem cells (CSCs) and a method of manufacturing the same. In particular, the present disclosure provides a method of manufacturing a multilayered cell sheet according to a single step culture procedure by using, as a three-dimensional matrix, a biodegradable natural polymer hydrogel and embedding CSCs in the hydrogel. The multilayered cell sheet of the present disclosure does not require any special device for the manufacturing, is manageable with good physicomechanical property, increases a cell engraftment rate after transplantation based on sufficient accumulation of various growth and protective factors and extracellular matrix between cells, and is also self-assembled by the cell-mediated hydrogel compaction, making nutrients transfer easy. Therefore, the multilayered cell sheet of the CSCs is expected to be usefully applicable as a therapeutic agent for myocardium regeneration.Type: ApplicationFiled: December 18, 2017Publication date: July 1, 2021Applicants: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Young-Il YANG, Ki-Dong PARK, Won-Jin LEE, Min-Young CHOI, Kyung-Min PARK, Yun-Ki LEE
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Publication number: 20200131479Abstract: The present invention relates to a preparation method of a spheroid using human-derived cardiac stem cells and a therapeutic use for ischemic heart disease using the myocardial regeneration effect thereof. The spheroid using the cardiac stem cells provided in the present invention has excellent myocardial differentiation ability and regenerative therapeutic ability as compared to existing cardiac stem cells, and thus may be used for the treatment of ischemic heart disease such as myocardial infarction.Type: ApplicationFiled: June 29, 2018Publication date: April 30, 2020Inventors: Seung Jin LEE, Young-il YANG
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Publication number: 20190070337Abstract: A method of manufacturing a multilayered cell sheet of neural crest stem cells (NCSCs), includes: (1) isolating and culturing NCSCs from peripheral nerves; (2) embedding the cultured NCSCs in a hydrogel; (3) culturing the hydrogel comprising the NCSCs embedded therein under stressed culture conditions in which a physical support is applied; and (4) culturing the resulting hydrogel of step (3) under non-stressed culture conditions in which a physical support is removed.Type: ApplicationFiled: December 18, 2017Publication date: March 7, 2019Applicant: INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUN DATIONInventors: Young-Il YANG, Won-Jin LEE, Jong-Tae KIM
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Publication number: 20060080916Abstract: A cubicle panel is disclosed wherein hangers underneath the panel are inserted into a frame and an upper end thereof is pushed upward and rotated, a magnetic catcher thereon is magnetically attached to the frame, and the panel is engaged to and/or disengaged from holes of a frame, such that cubicle assembly and disassembly are very simple, easy and less laborious because only both ends of the lower side of the panel are aligned and engaged to and/or disengaged from the holes of the frame, and the upper side of the panel is rotated and the panel is assembled and/or disassembled while both lower ends of the panel are inserted into the holes.Type: ApplicationFiled: October 13, 2004Publication date: April 20, 2006Inventor: Young-Il Yang
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Publication number: 20060048457Abstract: A cubicle with door panels is disclosed. The cubicle including frames composed of horizontal members and vertical members erected at both sides. Each frame is coupled with a plurality of panels at front and/or rear surfaces thereof, and at least one of the panels is formed with a vertically-openable door panel. The door panel comprises wiring hanger members each formed at the front side thereof with a plurality of wiring hangers and fixed lengthwise to the vertical member; a panel plate hinged to an upper distal end of the wiring hanger member for opening upwards; and resilient means coupled to a hinge connector of the wiring hanger member and the panel plate for maintaining an openness of the panel plate when the panel plate is opened, such that additional wirings, re-wirings or checks thereto can be easily conducted, and wirings can be performed at various heights of the frame.Type: ApplicationFiled: September 9, 2004Publication date: March 9, 2006Inventor: Young-Il Yang
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Publication number: 20040190987Abstract: A connecting apparatus for cubicle partitioning frames is disclosed. The connecting apparatus for connecting neighboring partitioning frames each formed with connecting holes comprises a connecting plate formed at one end thereof with a first hitching jaw for insertion into and passing through the connecting hole and a second hitching jaw formed at the other end thereof for not passing through the connecting hole. The apparatus further comprises a leaf spring for being insertedly hitched by the first hitching jaw of the connecting plate, and a connector housing for pressing the leaf spring to be insertedly hitched by the first hitching jaw of the connecting plate.Type: ApplicationFiled: August 27, 2003Publication date: September 30, 2004Applicant: FURSYS INCORPORATIONInventor: Young-Il Yang