Abstract: The present invention relates to an ensemble evolutionary chemical binding similarity (ensECBS) model, which is a chemical binding similarity searching method widely applicable as a powerful tool for representing an unknown relationship between chemicals by using evolutionary information of proteins binding to chemicals.

Abstract: A rapid immunoassay method and apparatus for detecting foot and mouth disease virus are disclosed. The method and test device permit pen-side testing of animals and provide test results within a relatively short time period. In a preferred embodiment, the method and apparatus provide a means for differentiating between FMDV-infected and FMDV-vaccinated animals.

Abstract: A rapid immunoassay method and apparatus for detecting foot and mouth disease virus are disclosed. The method and test device permit pen-side testing of animals and provide test results within a relatively short time period. In a preferred embodiment, the method and apparatus provide a means for differentiating between FMDV-infected and FMDV-vaccinated animals.

Abstract: Provided herein are uses of genes for HOG, Ras and cAMP signal transduction pathways to treat fungal infection. To regulate the HOG pathway of Cryptococcus neoformans, roles of SSK1, TCO2, SSK2, PBS2, HOG1, ENA1 and NHA1 genes were investigated to find that a biosynthesis level of ergosterol is increased when these genes are inhibited. When the genes are inhibited, a large amount of ergosterol is distributed on a fungal cell membrane. Accordingly, since there are many working points of an ergosterol-binding antifungal agent, an efficiency of the ergosterol-binding antifungal agent can be considerably improved. To regulate the Ras and cAMP pathways of Cryptococcus neoformans, roles of RAS1, RAS2, CDC24, GPA1, CAC1, ACA1, PKA1, HSP12 and HSP122 genes were investigated to find that a sensitivity to a polyene- or azole-based drug is increased when these genes are inhibited.

Abstract: Provided herein are uses of genes for HOG, Ras and cAMP signal transduction pathways to treat fungal infection. To regulate the HOG pathway of Cryptococcus neoformans, roles of SSK1, TCO2, SSK2, PBS2, HOG1, ENA1 and NHA1 genes were investigated to find that a biosynthesis level of ergosterol is increased when these genes are inhibited. When the genes are inhibited, a large amount of ergosterol is distributed on a fungal cell membrane. Accordingly, since there are many working points of an ergosterol-binding antifungal agent, an efficiency of the ergosterol-binding antifungal agent can be considerably improved. To regulate the Ras and cAMP pathways of Cryptococcus neoformans, roles of RAS1, RAS2, CDC24, GPA1, CAC1, ACA1, PKA1, HSP12 and HSP122 genes were investigated to find that a sensitivity to a polyene- or azole-based drug is increased when these genes are inhibited.

Abstract: Provided herein are uses of genes for HOG, Ras and cAMP signal transduction pathways to treat fungal infection. To regulate the HOG pathway of Cryptococcus neoformans, roles of SSK1, TCO2, SSK2, PBS2, HOG1, ENA1 and NHA1 genes were investigated to find that a biosynthesis level of ergosterol is increased when these genes are inhibited. When the genes are inhibited, a large amount of ergosterol is distributed on a fungal cell membrane. Accordingly, since there are many working points of an ergosterol-binding antifungal agent, an efficiency of the ergosterol-binding antifungal agent can be considerably improved. To regulate the Ras and cAMP pathways of Cryptococcus neoformans, roles of RAS1, RAS2, CDC24, GPA1, CAC1, ACA1, PKA1, HSP12 and HSP122 genes were investigated to find that a sensitivity to a polyene- or azole-based drug is increased when these genes are inhibited.

Abstract: The invention provides a PCB type dual band patch antenna and a wireless communication module incorporating the antenna. The antenna includes a substrate. A ground pattern is formed on the substrate. A radiating patch is formed on the substrate to be spaced apart from the ground pattern at a predetermined distance. The radiating patch includes an input arm and a main radiator which are divided by a slot with ‘L’ and inverse ‘L’ shapes combined. The main radiator has an open terminal opposing the input arm across the slot. Also, a feeding part is connected to the input arm of the radiating patch to apply an electrical signal to the radiating patch. Further, wireless devices are integrally mounted on the PCB substrate used for the antenna, thereby achieving a high efficiency and wide-bandwidth dual band patch antenna and a minimal-sized and low-cost wireless communication module.

Abstract: A rapid immunoassay method and apparatus for detecting foot and mouth disease virus are disclosed. The method and test device permit pen-side testing of animals and provide test results within a relatively short time period. In a preferred embodiment, the method and apparatus provide a means for differentiating between FMDV-infected and FMDV-vaccinated animals.

Abstract: Provided is an analog-to-digital converter. The analog-to-digital converter includes a resistor string for generating a plurality of reference voltages; a plurality of differential difference amplifiers for detecting zero-crossing points according to interpolation by using the plurality of reference voltages and input signals; and a plurality of comparators for receiving outputs of the plurality of differential difference amplifiers, detecting zero-crossing points according to 4X interpolation, and generating a digital code corresponding to the input signals.

Abstract: Provided are an ultra wideband (UWB) system and a method for operating the same. The UWB system includes a baseband unit for modulating/demodulating an impulse data signal and generating a power management control signal using burst hopping information, and an RF transmitting/receiving unit for transmitting/receiving a wireless signal and alternating between power-on/off states according to the power management control signal generated from the baseband unit. The UWB system can reduce power consumption by applying power source to the RF transmitting/receiving unit only at a time interval in which an impulse signal having a short time period and constituting transmitting/receiving data exists.

Abstract: A rapid immunoassay method and apparatus for detecting foot and mouth disease virus are disclosed. The method and test device permit pen-side testing of animals and provide test results within a relatively short time period. In a preferred embodiment, the method and apparatus provide a means for differentiating between FMDV-infected and FMDV-vaccinated animals.

Abstract: The invention provides a PCB type dual band patch antenna and a wireless communication module incorporating the antenna. The antenna includes a substrate. A ground pattern is formed on the substrate. A radiating patch is formed on the substrate to be spaced apart from the ground pattern at a predetermined distance. The radiating patch includes an input arm and a main radiator which are divided by a slot with ‘L’ and inverse ‘L’ shapes combined. The main radiator has an open terminal opposing the input arm across the slot. Also, a feeding part is connected to the input arm of the radiating patch to apply an electrical signal to the radiating patch. Further, wireless devices are integrally mounted on the PCB substrate used for the antenna, thereby achieving a high efficiency and wide-bandwidth dual band patch antenna and a minimal-sized and low-cost wireless communication module.

Abstract: The present invention relates generally to a spiral-patterned internal antenna having an open stub and a personal mobile terminal equipped with the same and, more particularly, to the pattern of an open stub. The spiral-patterned internal antenna of the present invention includes a main part having a spiral pattern; and an open stub connected to the main part. According to the present invention, an antenna for a terminal can be constituted regardless of the shape of a rear casing by using a spiral-patterned antenna having an open stub, and a highly efficient antenna can be formed using the suggested open stub.

Abstract: An internal antenna of a wireless communication terminal, in which internal style folded monopole antenna is installed, is provided. The internal antenna of a wireless communication terminal includes a folded monopole antenna. The folded monopole antenna includes two folded radiation planes having a quarter wavelength, and reactances loaded to predetermined positions of the two radiation planes. Therefore, a space for installing the antenna in the terminal is minimized, and due to the no directional characteristics, the internal antenna can be applied to a wireless communication system of dual bandwidths.

Abstract: The present invention relates to a diagnostic method of Peste des Petits Ruminants (PPR), a viral animal disease. More specifically, the invention relates to a new diagnostic method capable of detecting PPRV antibodies safely, simply and rapidly with recombinant Nucleocapsid (N) protein of PPR virus (PPRV) and specific monoclonal antibody against N protein from PPRV.

Abstract: The present invention provides a method for diagnosing foot-and-mouth disease virus infection, comprising the steps of applying a predetermined amount of a test sample to a loading region of a strip; coupling a detection reagent including a given labeling reagent to an analyte of interest in the test sample to form a complex therebetween; developing the complex onto a wicking membrane; and observing changes in appearance of a reactivity zone having at least more than one immobilized phase selected from antigen, antibody or hapten on the predetermined region of the wicking membrane, derived from FMDV or obtainable from FMDV through an immunological reaction to determine the presence or absence of foot-and-mouth disease virus infection.

Abstract: Disclosed is a wireless internal antenna for a home network and digital electric home appliance which comprises: a wireless antenna for a client having a tuning slot at an upper surface of a client device to realize an impedance matching at a band of IEEE802.11b (a band of 2.4 GHz) and having a certain type patch pole at a lower surface of the client device to have return characteristics at a band of IEEE802.11a (a band of 5 GHz); and a wireless antenna for a server, enabling transmission/reception to/from the client device, having an air slot at an upper surface of a server device and a feeding line at a lower surface thereof, and the server device is supported at a ground plate by a supporting portion installed at a lower part thereof.

Abstract: The present invention relates generally to a spiral-patterned internal antenna having an open stub and a personal mobile terminal equipped with the same and, more particularly, to the pattern of an open stub. The spiral-patterned internal antenna of the present invention includes a main part having a spiral pattern; and an open stub connected to the main part. According to the present invention, an antenna for a terminal can be constituted regardless of the shape of a rear casing by using a spiral-patterned antenna having an open stub, and a highly efficient antenna can be formed using the suggested open stub.

Abstract: The present invention relates to a diagnostic method of Peste des Petits Ruminants (PPR), a viral animal disease. More specifically, the invention relates to a new diagnostic method capable of detecting PPRV antibodies safely, simply and rapidly with recombinant Nucleocapsid (N) protein of PPR virus (PPRV) and specific monoclonal antibody against N protein from PPRV.

Abstract: A rapid immunoassay method and apparatus for detecting foot and mouth disease virus are disclosed. The method and test device permit pen-side testing of animals and provide test results within a relatively short time period. In a preferred embodiment, the method and apparatus provide a means for differentiating between FMDV-infected and FMDV-vaccinated animals.