Abstract: Provided are a biaxially oriented high-density polyethylene multilayer film, and a method for manufacturing the same. In an embodiment, a biaxially oriented high-density polyethylene multilayer film including a base layer and a skin layer formed on both surfaces of the base layer, wherein the base layer includes a high-density polyethylene and the skin layer includes a polypropylene, is provided. The biaxially oriented high-density polyethylene multilayer film according to an embodiment of the present disclosure has excellent heat resistance, transparency, and mechanical properties, and may provide a recyclable uni-material BOPE multilayer film.