Patents by Inventor Young Nyun PARK

Young Nyun PARK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for regulating expression of PROX1 or expression of telomerase reverse transcriptase comprising activity regulator or method for screening telomerase reverse transcriptase regulator
    Patent number: 12006498
    Abstract: In the present specification, on the basis of the correlation between prospero homeobox protein 1 (PROX1) and telomerase reverse transcriptase (TERT), a composition for regulating expression of TERT, a method for screening a TERT expression regulator, a composition for diagnosing a TERT expression status, a diagnostic kit, a method for providing information for diagnosis, or a method for providing information for cancer diagnosis are disclosed. Specifically, in one aspect, the PROX1 of the present disclosure may bind to a TERT promoter, in particular a mutant TERT promoter in which base substitution occurs at the ?124 or ?146 bp position to regulate the expression of TERT, and the expression of TERT in non-hepatitis B virus-associated liver cancer can be inhibited specifically among liver cancers.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: June 11, 2024
    Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Sang Hoon Jung, Young-Joo Kim, Dae-geun Song, Young Nyun Park, Jeong Eun Yoo, Hyung Jin Rhee, Youngsic Jeon
  • COMPOSITION FOR REGULATING EXPRESSION OF PROX1 OR EXPRESSION OF TELOMERASE REVERSE TRANSCRIPTASE COMPRISING ACTIVITY REGULATOR OR METHOD FOR SCREENING TELOMERASE REVERSE TRANSCRIPTASE REGULATOR
    Publication number: 20230250424
    Abstract: In the present specification, on the basis of the correlation between prospero homeobox protein 1 (PROX1) and telomerase reverse transcriptase (TERT), a composition for regulating expression of TERT, a method for screening a TERT expression regulator, a composition for diagnosing a TERT expression status, a diagnostic kit, a method for providing information for diagnosis, or a method for providing information for cancer diagnosis are disclosed. Specifically, in one aspect, the PROX1 of the present disclosure may bind to a TERT promoter, in particular a mutant TERT promoter in which base substitution occurs at the -124 or -146 bp position to regulate the expression of TERT, and the expression of TERT in non-hepatitis B virus-associated liver cancer can be inhibited specifically among liver cancers.
    Type: Application
    Filed: October 19, 2018
    Publication date: August 10, 2023
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Sang Hoon JUNG, Young-Joo KIM, Dae-geun SONG, Young Nyun PARK, Jeong Eun YOO, Hyung Jin RHEE, Youngsic JEON