Publication number: 20090220431
Abstract: The present invention relates to a manganese-containing metal oxide nanoparticle-based magnetic resonance imaging (MRI) contrast agent, which is characterized in that: The core of it comprises 1 to 1000 nm-sized manganese-containing metal oxide nanoparticles which include MnO a (0<a<5) or MnMbOe (wherein M is at least one metal atom selected from the group consisting of a Group 1 or 2 element such as Li, Na, Be, Ca, Ge, Mg, Ba, Sr and Ra, a Group 13 element such as Ga and In, a transition metal element such as Y, Ta, V, Cr, Co, Fe, Ni, Cu, Zn, Ag, Cd and Hg, and lanthanide or actinide group elements such as La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm and Yb, 0<b<5 and 0<c<10); preferably MnM?dFeeOf (wherein M? is at least one metal atom selected from the group consisting of a Group 1 or 2 element such as Li, Na, Be, Ca, Ge, Mg, Ba, Sr and Ra, a Group 13 element such as Ga and In, a transition metal element such as Y, Ta, V, Cr, Co, Fe, Ni, Cu, Zn, Ag, Cd and Hg, and lanthanide or acti
Type:
Application
Filed:
December 1, 2006
Publication date:
September 3, 2009
Inventors:
Jin-Woo Cheon, Young-Wook Jun, Jae-Hyun Lee, Jung-Wook Suh, Jin-Suck Suh, Seung-Jin Ko, Yong-Min Huh, Ho-Taek Song