Patents by Inventor Youngjae Choe

Youngjae Choe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230159872
    Abstract: A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
    Type: Application
    Filed: November 16, 2022
    Publication date: May 25, 2023
    Inventors: Antonio Varone, Norman Wen, Daniel Levner, Richard Novak, Lori McPartlin, Donald E. Ingber, Youngjae Choe, Lian Leng, Justin K. Nguyen
  • Publication number: 20220403313
    Abstract: A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
    Type: Application
    Filed: August 16, 2022
    Publication date: December 22, 2022
    Inventors: Antonio Varone, Norman Wen, Daniel Levner, Richard Novak, Lori McPartlin, Donald E. Ingber, Youngjae Choe, Lian Leng, Justin K. Nguyen
  • Patent number: 11505773
    Abstract: A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: November 22, 2022
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Antonio Varone, Norman Wen, Daniel Levner, Richard Novak, Lori McPartlin, Donald E. Ingber, Youngjae Choe, Lian Leng, Justin K. Nguyen
  • Publication number: 20180346859
    Abstract: A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 6, 2018
    Inventors: Antonio Varone, Norman Wen, Daniel Levner, Richard Novak, Lori McPartlin, Donald E. Ingber, Youngjae Choe, Lian Leng, Justin K. Nguyen
  • Publication number: 20180080925
    Abstract: A microfluidic system for determining a response of cells comprises one or more fluid pumps. The one or more fluid pumps move a fluid across cells within a microfluidic device. The microfluidic device includes a microchannel at least partially defined by a surface having cells adhered thereto, a first port at one end of the microchannel, and a second port at an opposing end of the microchannel. The one or more fluid pumps move the fluid across the cells in a first direction toward the second port and then move the fluid across the cells in a second direction toward the first port.
    Type: Application
    Filed: March 31, 2016
    Publication date: March 22, 2018
    Inventors: Kambez Hajipouran Benam, Richard Novak, Josiah Sliz, Thomas Charles Ferrante, Donald Elliot Ingber, Youngjae Choe